AIM: To investigate the effects of Recql5 deficiency on liver injury induced by lipopolysaccharide/D-galactosamine（LPS/D-Gal）.METHODS: Liver injury was induced in wild type（WT） or Recql5-deficient mice using LPS/D-Gal,and assessed by histological,serum transaminases,and mortality analyses. Hepatocellular apoptosis was quantified by transferase d UTP nick end labeling assay and Westernblot analysis of cleaved caspase-3. Liver inflammatory chemokine and cytochrome P450 expression was analyzed by q... 

【文章來(lái)源】：World Journal of Gastroenterology. 2015,21(36)SCI

【文章頁(yè)數(shù)】：10 頁(yè)

【參考文獻(xiàn)】：
期刊論文
[1]Effect of Recql5 deficiency on the intestinal tumor susceptibility of Apcmin mice[J]. Yiduo Hu,Xincheng Lu,Guangbin Luo,Department of Genetics,Case Comprehensive Cancer Center and University Hospitals of Cleveland,Case Western Reserve University,Cleveland,OH 44106,United States Yiduo Hu,Department of Cancer Biology,Dana-Farber Cancer Institute,Boston,MA 02115,United States.  World Journal of Gastroenterology. 2010(12)



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