【摘要】：目的觀察年齡對胃排空、胃中間橫帶(MTB)和胃內食物分布的影響。方法 50例健康志愿者按年齡不同分為青年組、中年組和老年組,進食99mTc-DTPA標記的試餐后利用雙探頭SPECT采集圖像,通過計算機產生的像素將胃的每幀影像劃分為近端胃、MTB、遠端胃,分別測定、計算半排空時間、90 min胃內殘留率、不同時相胃各部分面積、計數(shù)/像素比等。結果老年組近端胃半排空時間較青年組、中年組縮短(P0.05),遠端胃90 min胃內核素殘留率較青年組、中年組增多(均P0.05);老年組近端胃60、90 min時相面積較青年組、中年組明顯減少(P0.05)。30、60、90 min時相老年組遠端胃面積較青年組、中年組明顯增加(均P0.05);在30、60、90 min時相老年組遠端胃計數(shù)/像素比較青年組、中年組增加(P0.05)。老年組0、30、60、90 min MTB面積較青年組、中年組增寬(P0.05)。結論胃排空并不隨著年齡的增加而改變,但老年人進食后存在胃內食物分布異常,可能與MTB增寬有關。
[Abstract]:Objective to observe the effect of age on gastric emptying, gastric transverse band (MTB) and gastric food distribution. Methods according to the age of 50 healthy volunteers, 50 healthy volunteers were divided into youth group, middle-aged group and elderly group according to their age. After eating 99mTc-DTPA marked test meal, the images were collected by double-probe SPECT. The images of each frame of stomach were divided into proximal stomach and MTB, distal stomach by computer. The half emptying time, 90 min gastric residual rate, the area of different parts of stomach, count / pixel ratio and so on were measured. Results the time of proximal gastric emptying in the elderly group was shorter than that in the young group (P 0.05), the residual rate of nuclide in the distal stomach 90 min in the distal stomach was higher than that in the young group, and the 90 min phase area in the elderly group was significantly lower than that in the young group (P 0.05). 30, 60, 90 min in the elderly group was significantly higher than that in the young group, and the area of the distal stomach in the middle age group was significantly higher than that in the middle age group (P 0.05). At 30, 60, 90 min, the distal stomach count / pixel in the elderly group was higher than that in the young group, and that in the middle-aged group was higher than that in the young group (P 0.05). The area of 90 min MTB in the elderly group was wider than that in the young group and middle-aged group (P 0.05). Conclusion gastric emptying does not change with the increase of age, but the abnormal distribution of gastric food in the elderly after eating may be related to the widening of MTB.
【作者單位】： 蘭州大學第一醫(yī)院老年科;蘭州大學第一醫(yī)院核醫(yī)學科;蘭州大學第一醫(yī)院消化科;甘肅中醫(yī)藥大學附屬醫(yī)院超聲科;
【基金】：甘肅省自然基金資助項目(1308RJZA219) 甘肅省胃腸病重點實驗室開放課題基金資助(gswcky-2012-004)
【分類號】：R573

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