發(fā)布時間：2019-05-08 04:59

【摘要】：目的探討胃黏膜中不同形態(tài)幽門螺桿菌感染引起的胃部疾病的病理特點,降低胃部幽門螺桿菌感染率。方法選取2011年4月-2014年3月行胃黏膜活檢的患者219例,采用不同的染色方法觀察幽門螺桿菌的形態(tài),并觀察胃黏膜的形影病理學改變;采用SPSS13.0軟件進行分析。結果螺旋狀伴球形幽門螺桿菌男性患者所占比例明顯高于單純球形幽門螺桿菌患者,兩種形態(tài)幽門螺桿菌之間差異有統(tǒng)計學意義(P0.05);兩種形態(tài)幽門螺桿菌患者黏膜類型、炎癥類型以及是否伴有異型增生差異無統(tǒng)計學意義;螺旋狀伴球形幽門螺桿菌有炎癥活動、重度炎癥、有濾泡形成者分別占79.35%、55.43%和50.00%;單純球形幽門螺桿菌患者分別占43.75%、25.00%和25.00%,螺旋狀伴球形幽門螺桿菌明顯高于單純球形螺桿菌,兩種形態(tài)比較差異有統(tǒng)計學意義(P0.05)。結論球形幽門螺桿菌與螺旋狀幽門螺桿菌均對胃黏膜具有致病性,且螺旋狀幽門螺桿菌的致病性更強,而男性存在該形態(tài)螺桿菌相對較多,臨床應予以注意。
[Abstract]:Objective to investigate the pathological characteristics of gastric diseases caused by different forms of Helicobacter pylori infection in gastric mucosa and to reduce the infection rate of Helicobacter pylori in gastric mucosa. Methods from April 2011 to March 2014, different staining methods were used to observe the morphology of Helicobacter pylori and the morphological and pathological changes of gastric mucosa, and the results were analyzed by SPSS13.0 software. Results the proportion of male patients with spiral helicobacter pylori was significantly higher than that of patients with pure spherical Helicobacter pylori, and there was a significant difference between the two forms of Helicobacter pylori (P0.05). There was no significant difference in mucosal type, inflammatory type and dysplasia between the two forms of Helicobacter pylori. Helicobacter pylori had inflammatory activity, severe inflammation and follicular formation accounted for 79.35%, 55.43% and 50.00% respectively. Patients with simple spherical Helicobacter pylori accounted for 43.75%, 25.00% and 25.0%, respectively. Spiral Helicobacter pylori with spherical Helicobacter pylori was significantly higher than pure spherical Helicobacter pylori, and there was significant difference between the two groups (P0.05). Conclusion both spherical Helicobacter pylori and helix Helicobacter pylori have pathogenicity to gastric mucosa, and the pathogenicity of spiral Helicobacter pylori is stronger than that of male, so it is necessary to pay attention to it in clinical practice. [WT5 "HZ] [WT5" HZ] conclusion [WT5 "BZ]
【作者單位】： 達州職業(yè)技術學院病理學教研室;達州職業(yè)技術學院病原微生物及免疫學教研室;四川省達縣人民醫(yī)院內(nèi)二科;
【基金】：四川省衛(wèi)生廳基金資助項目(CW-2011B-092)
【分類號】：R573

【相似文獻】

相關期刊論文 前10條

1 韓雷;佘菲菲;;球形幽門螺桿菌研究進展[J];海南醫(yī)學;2006年08期

2 葉兵;王鈞;;球形幽門螺桿菌的研究進展[J];醫(yī)學動物防制;2007年05期

3 陳月秀,佘菲菲;球形幽門螺桿菌非“L”型細菌[J];福建醫(yī)科大學學報;1997年04期

4 佘菲菲,蘇東輝,陳月秀,朱蘋;球形幽門螺桿菌分子生物學研究[J];中國微生態(tài)學雜志;1999年01期

5 吳小茜;佘菲菲;李能;鄭秀芬;陳月秀;;嗜酸乳桿菌對球形幽門螺桿菌的細胞黏附和增殖作用的影響[J];中國人獸共患病學報;2010年11期

6 佘菲菲,朱蘋,史碧山,蘇東輝,強華,陳月秀,鄭秀芬;球形幽門螺桿菌致細胞空泡變性毒力研究[J];中國人獸共患病雜志;2000年02期

7 佘菲菲,蘇東輝,朱蘋,周琳瑛,俞樹高,陳月秀;抗生素誘變的球形幽門螺桿菌定居毒力的研究[J];中華消化雜志;1999年03期

8 吳小茜;佘菲菲;李能;陳月秀;;嗜酸乳桿菌對螺旋形和球形幽門螺桿菌黏附拮抗作用的研究[J];福建醫(yī)科大學學報;2009年05期

9 陳豪,張靜,佘菲菲,陳月秀;球形幽門螺桿菌對SGC-7901細胞增殖的影響[J];中國微生態(tài)學雜志;2004年02期

10 鄧朝暉,許春娣,陳舜年,奚容平;圓球形幽門螺桿菌生物學性狀的研究[J];上海醫(yī)學;2003年06期

相關碩士學位論文 前2條

1 韓雷;球形幽門螺桿菌對胃上皮細胞增殖與凋亡及細胞內(nèi)轉錄因子Egr-1表達的影響[D];福建醫(yī)科大學;2006年

2 丁惠;球形幽門螺桿菌高表達基因的篩選及其克隆與真核表達[D];福建醫(yī)科大學;2003年

，

本文編號：2471638