節(jié)食減重與有氧運動對非酒精性脂肪肝的影響研究
發(fā)布時間:2019-03-22 10:39
【摘要】:目的比較節(jié)食減重與有氧運動分別對非酒精性脂肪肝(NAFLD)患者的改善作用。方法選取2013年5月—2015年5月在華中科技大學同濟醫(yī)學院附屬普愛醫(yī)院消化內科門診及住院部確診為NAFLD的患者30例,BMI 26~35 kg/m~2,平均BMI(31.8±1.6)kg/m~2。采用隨機數(shù)字表法將所有患者分為A組和B組,每組15例。A組患者采用節(jié)食減重治療,保證每天的飲食熱量控制在1 500 kcal,不進行任何有氧運動。B組患者采用有氧運動治療,每周運動3次,每次運動心率控制在最大心率(HRmax)的45%~55%,每周運動時間為150 min,同時保持既有飲食習慣,不因為運動額外增加飲食,共運動4周。比較兩組干預前后ALT、空腹血糖(FPG)、血非酯化脂肪酸(FFA)、空腹胰島素(INS)水平及胰島素抵抗指數(shù)(HOMA-IR)、內臟脂肪組織(VAT)面積。結果兩組性別、年齡比較,差異無統(tǒng)計學意義(P0.05);兩組干預前后體質量、BMI比較,差異均無統(tǒng)計學意義(P0.05)。兩組干預前ALT、FPG、FFA、INS水平及HOMA-IR比較,差異無統(tǒng)計學意義(P0.05);兩組干預后ALT、FPG、INS水平及HOMA-IR比較,差異無統(tǒng)計學意義;B組干預后FFA水平低于A組,差異有統(tǒng)計學意義(P0.05)。兩組干預前VAT面積比較,差異無統(tǒng)計學意義(P0.05);B組干預后VAT面積小于A組,差異有統(tǒng)計學意義(P0.05)。結論有氧運動比節(jié)食減重對NAFLD的改善作用更明顯。
[Abstract]:Objective to compare the effects of diet weight loss and aerobic exercise on non-alcoholic fatty liver (NAFLD) patients. Methods from May 2013 to May 2015, 30 patients with NAFLD diagnosed in the Department of Gastroenterology and inpatient Department of Tongji Medical College affiliated to Huazhong University of Science and Technology were selected. The average BMI of BMI 26 / 35 kg/m~2, was (31.8 鹵1.6) kg/m~2.. All patients were divided into two groups: group A (n = 15) and group B (n = 15). The patients in group A were treated with diet and weight loss to keep the daily diet calorie control at 1,500 kcal,. The patients in group B were treated with aerobic exercise, 3 times a week, and the heart rate of each exercise was controlled at 45% / 55% of the maximum heart rate (HRmax), and the weekly exercise time was 150 min, while maintaining the existing eating habits. A total of 4 weeks of exercise does not result in an extra diet due to exercise. Fasting blood glucose (FPG), fasting insulin (INS) (INS), insulin resistance index (HOMA-IR) and visceral adipose tissue (VAT) area were compared between the two groups before and after ALT, intervention. Results there was no significant difference in sex and age between the two groups (P0.05); there was no significant difference in body mass and BMI between the two groups before and after intervention (P0.05). There was no significant difference in the levels of ALT,FPG,FFA,INS and HOMA-IR between the two groups before intervention (P0.05), and there was no significant difference in the levels of ALT,FPG,INS and HOMA-IR between the two groups after intervention. After intervention, the level of FFA in group B was lower than that in group A, the difference was statistically significant (P0.05). There was no significant difference in the VAT area between the two groups before intervention (P0.05). The VAT area in the); B group was smaller than that in the A group after intervention, and the difference was statistically significant (P0.05). Conclusion aerobic exercise is more effective than diet in improving NAFLD.
【作者單位】: 華中科技大學同濟醫(yī)學院附屬普愛醫(yī)院消化內科;
【分類號】:R575.5
本文編號:2445520
[Abstract]:Objective to compare the effects of diet weight loss and aerobic exercise on non-alcoholic fatty liver (NAFLD) patients. Methods from May 2013 to May 2015, 30 patients with NAFLD diagnosed in the Department of Gastroenterology and inpatient Department of Tongji Medical College affiliated to Huazhong University of Science and Technology were selected. The average BMI of BMI 26 / 35 kg/m~2, was (31.8 鹵1.6) kg/m~2.. All patients were divided into two groups: group A (n = 15) and group B (n = 15). The patients in group A were treated with diet and weight loss to keep the daily diet calorie control at 1,500 kcal,. The patients in group B were treated with aerobic exercise, 3 times a week, and the heart rate of each exercise was controlled at 45% / 55% of the maximum heart rate (HRmax), and the weekly exercise time was 150 min, while maintaining the existing eating habits. A total of 4 weeks of exercise does not result in an extra diet due to exercise. Fasting blood glucose (FPG), fasting insulin (INS) (INS), insulin resistance index (HOMA-IR) and visceral adipose tissue (VAT) area were compared between the two groups before and after ALT, intervention. Results there was no significant difference in sex and age between the two groups (P0.05); there was no significant difference in body mass and BMI between the two groups before and after intervention (P0.05). There was no significant difference in the levels of ALT,FPG,FFA,INS and HOMA-IR between the two groups before intervention (P0.05), and there was no significant difference in the levels of ALT,FPG,INS and HOMA-IR between the two groups after intervention. After intervention, the level of FFA in group B was lower than that in group A, the difference was statistically significant (P0.05). There was no significant difference in the VAT area between the two groups before intervention (P0.05). The VAT area in the); B group was smaller than that in the A group after intervention, and the difference was statistically significant (P0.05). Conclusion aerobic exercise is more effective than diet in improving NAFLD.
【作者單位】: 華中科技大學同濟醫(yī)學院附屬普愛醫(yī)院消化內科;
【分類號】:R575.5
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