【摘要】：目的探究失代償期原發(fā)性肝硬化患者合并血流感染的臨床特征、特點(diǎn)。方法選取2013年5月-2016年5月于醫(yī)院接受治療的1043例失代償期原發(fā)性肝硬化患者,回顧性調(diào)查患者的一般資料發(fā)病率及感染患者體征、病發(fā)相關(guān)因素,同時對患者感染血樣進(jìn)行培養(yǎng),診斷其病原菌,調(diào)查患者中性粒細(xì)胞以及白細(xì)胞數(shù)目及預(yù)后情況。結(jié)果失代償期肝硬化合并血流感染患者112例,感染率為10.73%,有發(fā)熱36~38℃29例占27.35%,發(fā)熱38℃43例占40.57%,畏寒56例占52.83%。住院次數(shù)和曾接受侵襲性操作與血流感染有相關(guān)性(P0.05);培養(yǎng)病原菌共110株,其中革蘭陰性菌69株占62.73%,以大腸埃希菌為主;革蘭陽性菌41株占37.27%,金黃色葡萄球菌為主,兩種及兩種以上病原菌感染14例占13.21%;失代償期肝硬化合并血流感染患者中性粒細(xì)胞數(shù)目比例0.75有87例占82.08%,白細(xì)胞數(shù)目(10.96±2.12)×109/L,普通肝硬化患者中性粒細(xì)胞數(shù)目比例0.75有123例占13.21%,白細(xì)胞數(shù)目(7.89±2.38)×109/L,差異具有統(tǒng)計學(xué)意義(P0.05);預(yù)后療效中,失代償期肝硬化合并血流感染患者有效59.43%,無效40.56%,死亡率11.32%。結(jié)論失代償期肝硬化患者合并血流感染發(fā)病率高,預(yù)后效果差,且發(fā)病特征不明顯;減少住院次數(shù)和侵襲性操作,保證手術(shù)無菌環(huán)境有利于預(yù)防血流感染;以中性粒、白細(xì)胞進(jìn)行初期檢驗比血樣培養(yǎng)結(jié)果耗時短,能盡早進(jìn)行初期預(yù)后,配合血樣培養(yǎng)的準(zhǔn)確結(jié)果,有助于提早診斷時間。
[Abstract]:Objective to investigate the clinical features and characteristics of blood flow infection in patients with decompensated primary liver cirrhosis. Methods 1043 patients with decompensated primary liver cirrhosis who were treated in hospital from May 2013 to May 2016 were investigated retrospectively. At the same time, the infected blood samples were cultured, the pathogenic bacteria were diagnosed, and the neutrophil and leukocyte count and prognosis were investigated. Results 112 patients with decompensated liver cirrhosis complicated with blood flow infection, the infection rate was 10.73. There were 29 cases of fever 36 ~ 38 鈩，

本文編號：2236398