【摘要】：目的:探討急性胰腺炎局部并發(fā)癥的發(fā)生率及嚴重程度與病因相關性。方法:采用回顧性分析方法,收集我市部分三甲醫(yī)院2010-2015年2227例急性胰腺炎(Acute pancreatitis AP)患者一般資料,分析其病因與局部并發(fā)癥發(fā)生率以及嚴重程度的相關性。結果:研究中2227例急性胰腺炎患者病因分布為膽源性1137例(51.0%),代謝性741例(33.3%),酒精性349例(15.7%);局部并發(fā)癥的總發(fā)生率為39%,其中膽源性489例(43.0%),代謝性269例(36.3%),酒精性111例(31.6%),膽源性AP局部并發(fā)癥的發(fā)生率高于其他兩組,酒精性與代謝性AP局部并發(fā)癥發(fā)生率無統(tǒng)計學差異,按照胰周滲液累及的部位、數(shù)量將局部并發(fā)癥分為輕中重三級,性別、年齡對于局部并發(fā)癥的嚴重程度均無統(tǒng)計學差異(P0.05),膽源性AP局部并發(fā)癥比代謝性AP(P=0.000)和酒精性AP嚴重(P=0.015),代謝性AP和酒精性AP在局部并發(fā)癥的嚴重程度上無明顯差異(P0.05)。結論:膽源性AP局部并發(fā)癥發(fā)生率高于代謝性組和酒精性組,膽源性組的局部并發(fā)癥也較其他兩組嚴重,可見保守治療對于膽源性AP的療效不及其他病因類型的AP,因此在臨床上處理膽源性AP時應及時解除膽道梗阻,而不能僅僅對炎癥滲出情況進行干預。
[Abstract]:Objective: to investigate the incidence and severity of local complications in acute pancreatitis. Methods: the general data of 2227 patients with acute pancreatitis (Acute pancreatitis AP) from 2010 to 2015 in some third Class A Hospitals of our city were collected by retrospective analysis, and the correlation between the etiology and the incidence of local complications as well as the severity of acute pancreatitis was analyzed. Results: the etiology of 2227 patients with acute pancreatitis were choledochogenic 1137 (51.0%), metabolic 741 (33.3%), alcoholic 349 (15.7%), and the total incidence of local complications was 390.The total incidence of local complications was 398cases (43.0%), including 489 cases (43.0%), 269cases (36.3%), 111cases (31.6%). The incidence of local complications of biliary AP was higher than that of the other two groups. There was no significant difference in the incidence of local complications between alcoholic and metabolic AP. According to the location of peripancreatic effusion, the number of local complications was divided into light, medium and heavy levels, sex, Age had no significant difference in the severity of local complications (P0.05). Local complications of biliary AP were more serious than those of metabolic AP (P0. 000) and alcoholic AP (P0. 015). There was no significant difference in the severity of local complications between metabolic AP and alcoholic AP (P0.05). Conclusion: the incidence of local complications of biliary AP is higher than that of metabolic and alcoholic groups, and the local complications of biliary AP are more serious than those of the other two groups. It can be seen that the curative effect of conservative treatment on biliary AP is not as good as that of other etiological types of AP,. Therefore, the biliary obstruction should be relieved in clinical treatment of biliary AP, and the inflammatory exudation should not be interfered with.
【學位授予單位】：重慶醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R576

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