【摘要】：目的：對(duì)比分析福建醫(yī)科大學(xué)附屬第一醫(yī)院消化內(nèi)科近年收治的上消化道出血（UGIH）病例與12年前該疾病的發(fā)病情況，，探討其病因及相關(guān)因素關(guān)系變化，總結(jié)規(guī)律，提高對(duì)上消化道出血發(fā)病特點(diǎn)的認(rèn)識(shí) 方法：收集福建醫(yī)科大學(xué)附屬第一醫(yī)院消化內(nèi)科2009年5月-2013年4月期間825例UGIH住院患者的臨床資料與1992年-2001年期間1150例住院的UGIH病例，就其年齡、性別、發(fā)病季節(jié)及病因分布進(jìn)行對(duì)比分析 結(jié)果：①與12年前相比，UGIH平均發(fā)病年齡約增加了5歲，老年人總發(fā)病率上升11.21%；青年組中DU發(fā)病率呈下降趨勢(shì)（P0.01）；中年組中GC、AGML發(fā)病下降（均P0.05）；老年組中GU發(fā)病率上升（P0.01），GC、AGML發(fā)病則下降（均P0.01）。②12年來(lái)UGIH患者總體性別比例無(wú)顯著變化（P0.05），男性發(fā)病率均大于女性，其中GU男女性發(fā)病均上升（均P0.01），但其男女比值有下降（P0.05）。③UGIH各季節(jié)發(fā)病不完全相同，但總體都是冬春季發(fā)病率大于夏秋季（P0.05）；與12年前相比較，夏季發(fā)病率上升（P0.05），冬季發(fā)病率下降（P0.05）；春季里CU發(fā)病上升（P0.01），GC、AGML則下降（均P㩳0.05）；夏季DU、AGML發(fā)病率下降（均P0.05），GU、CU上升（均P0.01）；秋季DU下降（P0.01），GU發(fā)病上升（P0.01）；冬季DU發(fā)病下降（P0.05），CU上升（P0.01）。④UGIH主要病因仍是以DU、GU、CU、EGV、GC、AGML為多，與12年前相比DU、GC、AGML發(fā)病均呈下降趨勢(shì)（均P0.01），GU、CU、MWS發(fā)病則上升（均P0.01）。 結(jié)論：十二年來(lái)，UGIH的病因分布及相關(guān)因素的關(guān)系發(fā)生著較大的變化，與十二年前相比，UGIH發(fā)病平均年齡增加，老年人總發(fā)病率呈上升趨勢(shì)。男性發(fā)病均大于女性，其中GU發(fā)病中，男女性別比例明顯下降。夏季發(fā)病率上升，冬季發(fā)病有所下降。PU仍是UGIH的首要病因，DU、GC、AGML發(fā)病均呈下降趨勢(shì)，GU、CU、MWS發(fā)病則有明顯上升。
[Abstract]:Objective: to compare and analyze the incidence of upper gastrointestinal hemorrhage (UGIH) in recent years in the Department of Digestive Medicine, the first affiliated Hospital of Fujian Medical University. Methods to improve the understanding of the characteristics of upper gastrointestinal hemorrhage: collect the clinical data of 825 inpatients with UGIH from May 2009 to April 2013, Department of Digestive Medicine, the first affiliated Hospital of Fujian Medical University 1150 inpatients with UGIH, Compared with 12 years ago, the average age of UGIH increased by 5 years, and the total incidence rate of the elderly increased by 11.21 years. The incidence of DU decreased in the young group (P0.01), in the middle-aged group (P0.05), in the elderly group (P0.01), the incidence of GCU in the elderly group decreased (P0.01). There was no significant change in the overall sex ratio of the patients with UGIH in the past 212 years (P0.05), and the incidence rate of the male was higher than that of the female. The incidence of gu increased in both sexes (P0.01), but the ratio of male and female decreased (P0.05) .3The incidence of UGIH was not identical in different seasons, but the incidence rate in winter and spring was higher than that in summer and autumn (P0.05); compared with 12 years ago, the incidence of GU was higher than that in summer and autumn (P0.05). The incidence of CU increased in summer (P0.05), decreased in winter (P0.05), decreased in spring (P0.01), decreased in summer (P0.05), increased (P0.01) in autumn (P0.01). In winter, the incidence of DU decreased (P0.05). 4 the main cause of UGIH was that the main cause of DUGU was still the AGML. Compared with 12 years ago, the incidence of DUGCU AGML decreased (P0.01) and the incidence of GUCUMWS increased (P0.01). Conclusion: in the past 12 years, the etiological factors and the related factors of UGIH have changed greatly. Compared with 12 years ago, the average age of UGIH incidence has increased, and the total incidence rate of the elderly has been on the rise. The incidence rate of males was higher than that of females, and the ratio of males and females decreased significantly in the onset of gu. The incidence of UGIH increased in summer, but decreased in winter. Pu was still the main cause of UGIH.
【學(xué)位授予單位】：福建醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R573.2

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