味覺敏感性與結(jié)腸疾病的相關(guān)性研究
發(fā)布時(shí)間:2018-07-09 18:13
本文選題:味覺 + 丙硫氧嘧啶; 參考:《南京師大學(xué)報(bào)(自然科學(xué)版)》2017年01期
【摘要】:以常熟市各大醫(yī)院腸鏡檢查者中的志愿者為受試對(duì)象,通過(guò)蘸涂法檢測(cè)其甜味、苦味閾值,結(jié)合腸鏡檢查報(bào)告和飲食問(wèn)卷調(diào)查,探討味覺敏感性與結(jié)腸疾病的關(guān)系.結(jié)果顯示,甜味、苦味敏感性均隨年齡增長(zhǎng)而下降.對(duì)所有受試對(duì)象進(jìn)行分析,結(jié)腸炎癥組與息肉組的苦味閾值較正常組顯著增高,而甜味閾值無(wú)顯著差異;但是炎癥組和息肉組的年齡顯著大于正常組.進(jìn)一步分析45~64歲年齡段(組間無(wú)年齡差異),結(jié)腸炎或息肉患者的甜味閾值顯著低于正常組,而苦味閾值沒有變化.該研究提示,甜味敏感性高的人群,膳食纖維攝入較少,罹患結(jié)腸疾病的風(fēng)險(xiǎn)較高.此外,甜味閾值測(cè)試對(duì)及早診治結(jié)腸炎或結(jié)腸息肉、預(yù)防結(jié)腸癌的發(fā)生以及保護(hù)人類健康具有重要價(jià)值.
[Abstract]:The subjects were volunteers of enteroscopy in major hospitals of Changshu city. The relationship between taste sensitivity and colonic diseases was investigated by dipping method to detect the threshold of sweetness and bitter taste, combined with the report of colonoscopy and dietary questionnaire. The results showed that the sensibility of sweet taste and bitter taste decreased with age. The bitter taste threshold of colitis group and polyp group was significantly higher than that of normal group, but there was no significant difference in sweet taste threshold, but the age of inflammatory group and polyp group was significantly higher than that of normal group. Further analysis showed that the sweet taste threshold of patients with colitis or polyp was significantly lower than that of the normal group, but the bitter taste threshold was not changed. The study suggests that people with high sweetness have a lower dietary fiber intake and a higher risk of colon disease. In addition, sweet taste threshold test has important value in early diagnosis and treatment of colitis or colonic polyps, prevention of colon cancer and protection of human health.
【作者單位】: 常熟理工學(xué)院生物與食品工程學(xué)院;常熟市第五人民醫(yī)院;
【基金】:國(guó)家自然科學(xué)基金(NSFC31200812) 國(guó)家級(jí)大學(xué)生創(chuàng)新創(chuàng)業(yè)訓(xùn)練計(jì)劃項(xiàng)目((201310333001) 江蘇省第五期“333工程”第三層次培養(yǎng)對(duì)象(2016) 常熟市醫(yī)藥科技計(jì)劃項(xiàng)目(csws201411)
【分類號(hào)】:R574.62
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1 盧琴;丙硫氧嘧啶引起中毒性肝炎2例[J];藥物流行病學(xué)雜志;2002年02期
,本文編號(hào):2110250
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