本文選題：非酒精性脂肪肝 + 代謝綜合征��； 參考：《現(xiàn)代預(yù)防醫(yī)學(xué)》2015年22期

【摘要】：目的通過流行病學(xué)調(diào)查,分析非酒精性脂肪性肝病(NAFLD)的相關(guān)危險(xiǎn)因素,以探討NAFLD與代謝綜合征(MS)的相關(guān)性。方法 873人依據(jù)體檢情況分為NAFLD組和非NAFLD組及MS組和非MS組,分析體重指數(shù)(BMI)、血壓、血脂、血糖(FBG)等因素與NAFLD的相關(guān)性。結(jié)果 (1)NAFLD患病率41.123%,男性患病率高于女性(χ2=21.804,P0.001)。MS患病率15.693%,MS組NAFLD患病率高于非MS組(χ2=99.171,P0.001)。(2)NAFLD組BMI、FBG、收縮壓(SBP)、舒張壓(DBP)、甘油三酯(TG)、膽固醇(TC)、低密度脂蛋白(LDL-C)、谷丙轉(zhuǎn)氨酶(ALT)、尿酸(UA)值均高于非NAFLD組(P0.001),谷草轉(zhuǎn)氨酶(AST)值高于非NAFLD組(t=3.242,P=0.001),HDL-C值低于非NAFLD組(t=3.510,P0.001);超重和(或)肥胖、高血糖、高血壓、高TG、低HDL-C、高尿酸血癥、MS陽性率均高于非NAFLD組(P0.001),肝功能異常陽性率高于非NAFLD組(t=10.119,P=0.002)。(3)NAFLD患病率隨著MS診斷標(biāo)準(zhǔn)中診斷項(xiàng)目的增多呈上升趨勢(χ2=239.918,P0.001)。結(jié)論 MS與NAFLD密切相關(guān),并相互影響。
[Abstract]:Objective to investigate the correlation between NAFLD and metabolic syndrome (MS) by analyzing the risk factors of nonalcoholic fatty liver disease (NAFLD). Methods 873 patients were divided into NAFLD group, non-NAFLD group, MS group and non-MS group according to physical examination. The correlation between body mass index (BMI), blood pressure, blood lipid, blood glucose (FBG) and NAFLD was analyzed. Results (1) the prevalence rate of NAFLD in males was higher than that in females (蠂 2: 21.804 / P0.001). The prevalence rate of MS was 15.693C. The prevalence rate of NAFLD in MS group was higher than that in non-MS group (蠂 2 99.171 P0.001). (2). Systolic blood pressure (SBP), diastolic blood pressure (DBP), triglyceride (TG), cholesterol (TC), low density lipoprotein cholesterol (LDL-C), alanine aminotransferase (alt), uric acid (UA) were all higher. The values of glutamic oxaloacetic transaminase (AST) were higher than those of non-NAFLD group (tnafLD) (t = 3.242) and HDL-C were lower than those of non-NAFLD group (t = 3.510p 0.001), and were overweight and / or obese, and the level of HDL-C was higher than that of non-NAFLD group (P 0.001). The positive rate of MS in hyperglycemia, hypertension, hyperglycemia, low HDL-Cand hyperuricemia group was higher than that in non-NAFLD group (P0.001), and the positive rate of abnormal liver function was higher than that in non-NAFLD group (tnd10.119P0.0002). (3). The prevalence rate of NAFLD increased with the increase of diagnostic items in MS diagnostic criteria (蠂 2239.918P 0.001). Conclusion MS is closely related to NAFLD and interacts with each other.
【作者單位】： 山東中醫(yī)藥大學(xué);山東中醫(yī)藥大學(xué)第一附屬醫(yī)院;
【分類號】：R589;R575.5

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本文編號：2092015