本文選題：骶神經(jīng)刺激 + 功能性便秘　； 參考：《青島大學(xué)》2014年碩士論文

【摘要】：目的：觀察骶神經(jīng)刺激對功能性便秘的療效,并從排便動力學(xué)評估骶神經(jīng)電刺激后對排便功能的影響并分析可能存在的機(jī)制,為骶神經(jīng)刺激治療臨床不同分型便秘提供客觀依據(jù)。 方法：1、選取明確診斷的功能性便秘患者180例,分為結(jié)腸慢傳輸型60例,出口梗阻型60例,混合型60例,采用數(shù)字隨機(jī)法隨機(jī)分為兩組。2、對照組予單純福松口服,治療組在福松治療的基礎(chǔ)上加用骶神經(jīng)刺激治療,治療以20日為1療程。3、在治療前及治療后分別進(jìn)行結(jié)直腸動力學(xué)檢查,并以便秘患者癥狀評分及生活質(zhì)量問卷評分(PAC-QOL)為主要觀察指標(biāo),療程結(jié)束后,兩組療效作組間比較。 結(jié)果：1、治療組動力學(xué)指標(biāo)較治療前顯著降低,與對照組相比較有顯著差異(P0.05),表明治療組療效明顯優(yōu)于對照組。2、治療組與對照組的便秘癥狀評分治療前與治療后相比有顯著性差異(P0.05),兩組間臨床癥狀評分相比較有顯著性差異(P0.05),表明治療組療效明顯優(yōu)于對照組。3、治療組與對照組的PAC-QOL評分治療前與治療后相比有顯著性差異(P0.05),兩組患者生活質(zhì)量均明顯提高,兩組間PAC-QOL評分相比較有顯著性差異(P0.05),表明治療組療效明顯優(yōu)于對照組。 結(jié)論：SNS是創(chuàng)傷小、療效好的治療功能性便秘的方法,可顯著改善患者的癥狀,提高患者的生活的質(zhì)量,改善結(jié)直腸動力,協(xié)調(diào)盆底肌群運(yùn)動,降低排便閾值。
[Abstract]:Objective: To observe the effect of sacral nerve stimulation on functional constipation, and to evaluate the effect of sacral nerve stimulation on defecation after the electric stimulation of the sacral nerve and to analyze the possible mechanisms of the sacral nerve stimulation, so as to provide an objective basis for the treatment of different clinical constipation by sacral nerve stimulation.
Methods: 1, 180 cases of functional constipation were selected and divided into 60 cases of colon slow transmission type, 60 cases of outlet obstruction type and 60 cases of mixed type. The patients were randomly divided into two groups of.2 by digital random method. The control group was given simple Fu Song oral administration. The treatment group was treated with sacral nerve stimulation on the basis of the treatment of Fu Song. The treatment was treated with 20 days as the 1 course of treatment, and the treatment was treated in the treatment of.3. The treatment group was treated with the treatment of 20 days. Colorectal kinetics was performed before and after treatment, and the symptoms score of constipation patients and quality of life questionnaire (PAC-QOL) were used as the main indexes. After the course of treatment, the two groups were compared.
Results: 1, the dynamic indexes of the treatment group were significantly lower than those before the treatment (P0.05), which showed that the curative effect of the treatment group was significantly better than that of the control group.2. The constipation symptom scores of the treatment group and the control group were significantly different before and after the treatment (P0.05), and there was a significant difference in the clinical symptom scores between the two groups (P0.05). P0.05) showed that the curative effect of the treatment group was obviously better than that of the control group.3. The PAC-QOL score of the treatment group and the control group was significantly different before and after the treatment (P0.05). The quality of life of the two groups was obviously improved, and the PAC-QOL score of the two groups was significantly different (P0.05), indicating that the curative effect of the treatment group was obviously better than that of the control group.
Conclusion: SNS is a minimally invasive and effective method for the treatment of functional constipation. It can significantly improve the patient's symptoms, improve the quality of the patient's life, improve the dynamic of the colorectal, coordinate the movement of the pelvic floor muscle group, and reduce the threshold of defecation.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R574.62

【引證文獻(xiàn)】

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1 曹江松;八毼穴電刺激配合生物反饋訓(xùn)練治療盆底失弛緩征的臨床研究[D];云南中醫(yī)學(xué)院;2016年

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本文編號：2064311