本文選題：肝炎 + 丙型　； 參考：《實(shí)用醫(yī)學(xué)雜志》2015年09期

【摘要】：目的:評(píng)價(jià)影響丙型肝炎肝硬化患者預(yù)后的相關(guān)危險(xiǎn)因素。方法:對(duì)我院2002-2011年期間收治的丙肝肝硬化患者資料進(jìn)行研究,并對(duì)其進(jìn)行規(guī)律隨訪。首先對(duì)各潛在預(yù)后相關(guān)危險(xiǎn)因素與生存情況或肝移植情況的關(guān)系分別進(jìn)行單因素分析,再將其有統(tǒng)計(jì)學(xué)意義的指標(biāo)分別納入Logistic回歸及COX回歸模型。結(jié)果:共納入572例丙肝患者,其中143例合并肝硬化,男103例(72.03%),平均年齡59(51~71)歲。在143例肝硬化患者中,57例(39.86%)患有糖尿病,41例(28.67%)有大量飲酒史,3例(2.10%)存在HBV感染。經(jīng)統(tǒng)計(jì)分析發(fā)現(xiàn),終末期肝病評(píng)分≥10分、糖尿病及合并HBV感染與無(wú)肝移植生存期有明顯相關(guān)性(P0.05),糖尿病與腹水、細(xì)菌感染及肝性腦病明顯相關(guān)(P0.05)。隨訪分析發(fā)現(xiàn)糖尿病與肝病腹水進(jìn)展、細(xì)菌感染、腎功能紊亂及肝癌有明顯相關(guān)性(P0.05)。結(jié)論:糖尿病是丙肝肝硬化患者預(yù)后的獨(dú)立危險(xiǎn)因素,控制糖尿病有可能提高該類患者的生存質(zhì)量。
[Abstract]:Objective: to evaluate the risk factors associated with the prognosis of patients with hepatitis C cirrhosis. Methods: the data of patients with cirrhosis of hepatitis C admitted from 2002 to 2011 in our hospital were studied and followed up regularly. First, univariate analysis was carried out on the relationship between each potential prognostic risk factor and survival condition or liver transplantation condition, and then the statistically significant indexes were included in logistic regression and Cox regression models. Results: a total of 572 patients with hepatitis C were included, 143 of whom were complicated with cirrhosis, 103 males (72.03%), with an average age of 59 years (51 / 71). Of 143 patients with liver cirrhosis, 57 (39.86%) had diabetes mellitus, 41 (28.67%) had heavy drinking history and 3 (2.10%) had HBV infection. Statistical analysis showed that the score of end-stage liver disease 鈮，

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