本文選題：第代雙源CT + 碘圖��； 參考：《中國(guó)醫(yī)學(xué)科學(xué)院學(xué)報(bào)》2017年01期

【摘要】：目的研究對(duì)于肝臟局灶性病變,第3代雙源CT的雙能成像碘圖參數(shù)與灌注成像灌注參數(shù)的相關(guān)性。方法以2015年11月至2016年8月在北京協(xié)和醫(yī)院經(jīng)臨床診斷為肝臟非囊性占位的33例患者為研究對(duì)象,運(yùn)用第3代雙源CT行肝臟灌注成像及雙能CT成像掃描,兩種掃描間隔15 min。于雙能CT動(dòng)、門脈期碘圖肝占位相對(duì)高、中、低密度區(qū)及正常肝右葉、肝左葉實(shí)質(zhì)內(nèi)繪制感興趣區(qū)(ROI),獲得碘圖CT值;于肝臟灌注圖像的相同位置繪制ROI,獲得肝動(dòng)脈灌注量(ALP)、門靜脈灌注量(PVP)、肝動(dòng)脈灌注指數(shù)(HPI)。采用Pearson相關(guān)性分析比較碘圖CT值與灌注參數(shù)相關(guān)性。結(jié)果動(dòng)脈期碘圖CT值與ALP(r=0.812,95%CI=0.728~0.885,P0.001)和PVP(r=-0.209,95%CI=-0.323~-0.073,P=0.007)顯著相關(guān),與HPI無顯著相關(guān)(r=0.058,95%CI=0.046~0.498,P=0.461)。門脈期碘圖CT值與PVP顯著相關(guān)(r=0.214,95%CI=0.072~0.361,P=0.005),與HPI無顯著相關(guān)(r=0.036,95%CI=-0.002~0.242,P=0.649)。雙能CT掃描動(dòng)脈期和門脈期的總有效劑量為(3.53±1.17)m Sv,明顯低于肝臟灌注的(14.53±0.45)m Sv(t=25.212,P0.001)。結(jié)論雙能CT成像動(dòng)脈期碘圖參數(shù)與肝臟灌注ALP和PVP顯著相關(guān),門脈期碘圖參數(shù)與PVP顯著相關(guān)。
[Abstract]:Objective to study the correlation between dual-energy imaging iodine parameters and perfusion imaging parameters of the third generation dual-source CT for focal liver lesions. Methods from November 2015 to August 2016, 33 patients who were clinically diagnosed as non-cystic occupying liver in Peking Union Hospital were studied. The third generation dual-source CT was used to perform hepatic perfusion imaging and dual-energy CT imaging. The interval between the two scans was 15 minutes. The right lobe of normal liver and the middle and low density area of the liver were drawn in the middle and low density area of the liver and the right lobe of the normal liver. The region of interest was drawn in the Zuo Ye parenchyma of the liver, and the CT value of the iodine graph was obtained. ROI was drawn at the same position of hepatic perfusion image to obtain hepatic artery perfusion volume (ALP), portal vein perfusion volume (PVP), hepatic artery perfusion index (HPI) and hepatic artery perfusion index (HPI). Pearson correlation analysis was used to compare the correlation between CT value and perfusion parameters. Results the CT value of arterial phase iodide was significantly correlated with ALP rn 0.812 ~ 95 CIQ 0.728 0.885U P0.001) and PVPr-0.209 ~ 95C CI-0.323- 0.073P0. 007), but not with HPI (r0.0595CI0.0460.498P0. 461 ~ 0. 461 ~ 0. 461 ~ 0. 461 ~ 0. 461 ~ 0. 595 CI 0.046 ~ 0. 498P ~ 0. 461 ~ 0. 461 ~ 0. 461 ~ 0. 461 ~ 0. 461). The CT value of portal phase iodography was significantly correlated with PVP (r = 0.214995), but had no significant correlation with HPI (n = 0.036,95CI-0.002 ~ 0.242P ~ (0.649). The total effective dose in arterial phase and portal phase was 3.53 鹵1.17mSv, which was significantly lower than that in hepatic perfusion group (14.53 鹵0.45mSvt, 25.212mSvt, P 0.001). Conclusion the arterial phase iodine parameters of dual-energy CT imaging are significantly correlated with hepatic perfusion of ALP and PVP, and portal phase iodine parameters are significantly correlated with PVP.
【作者單位】： 中國(guó)醫(yī)學(xué)科學(xué)院北京協(xié)和醫(yī)學(xué)院北京協(xié)和醫(yī)院放射科;中國(guó)醫(yī)學(xué)科學(xué)院北京協(xié)和醫(yī)學(xué)院北京協(xié)和醫(yī)院肝臟外科;
【基金】：國(guó)家臨床重點(diǎn)�？平ㄔO(shè)項(xiàng)目(2014) 衛(wèi)生公益性行業(yè)科研專項(xiàng)項(xiàng)目(201402019)~~
【分類號(hào)】：R816.5;R575

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