本文選題：胰腺感染 + 重癥急性胰腺炎��； 參考：《中華醫(yī)院感染學雜志》2015年09期

【摘要】：目的研究重癥急性胰腺炎(SAP)繼發(fā)胰腺感染的危險因素,為臨床診治提供參考。方法選取2012年6月-2013年12月醫(yī)院收治的SAP患者102例為研究對象,根據(jù)是否繼發(fā)胰腺感染將其分為感染組38例,未感染組64例;對胰腺感染的危險因素進行分析,采用SPSS17.0軟件對數(shù)據(jù)進行統(tǒng)計分析。結(jié)果胰腺感染率為37.25%;感染組共培養(yǎng)出69株病原菌,其中革蘭陰性菌占73.91%;革蘭陽性菌占26.09%;革蘭陰性桿菌對亞胺培南、美羅培南較敏感,敏感率為100.00%、92.11%;革蘭陽性菌對萬古霉素敏感,敏感率為100.00%;兩組血鈣(Ca2+)濃度、APACHEⅡ評分、糖尿病、低氧血癥、胰腺壞死分期、多器官功能障礙綜合征(MODS)、胃腸功能障礙、機械通氣時間、腸外營養(yǎng)時間比較差異有統(tǒng)計學意義(P0.05);logistic回歸分析顯示,低血Ca2+、合并糖尿病、MODS、Ⅲ期胰腺壞死、胃腸功能障礙≥7d是SAP繼發(fā)胰腺感染的獨立危險因素。結(jié)論 SAP繼發(fā)胰腺感染的危險因素復(fù)雜,對合并糖尿病、MODS、胰腺壞死患者采取積極預(yù)防措施,降低胰腺感染風險。
[Abstract]:Objective to study the risk factors of pancreatic infection secondary to severe acute pancreatitis (SAP) and to provide reference for clinical diagnosis and treatment. Methods 102 patients with SAP admitted in hospital from June 2012 to December 2013 were divided into infection group (n = 38) and uninfected group (n = 64) according to whether they had secondary pancreatic infection, and the risk factors of pancreatic infection were analyzed. The data were analyzed by SPSS17.0 software. Results the infection rate of pancreas was 37.25. 69 pathogenic bacteria were cultured in the infection group, of which 73.91 were Gram-negative bacteria, 26.09 were Gram-positive bacteria. Gram-negative bacilli were sensitive to imipenem and meropenem with a sensitivity rate of 100.00g / 92.110.Gram-positive bacteria were sensitive to vancomycin. The sensitivity rate was 100.00. the serum calcium concentration in the two groups was evaluated by Apache 鈪，

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