111例胃Dieulafoy病出血臨床特征及再出血危險因素分析
發(fā)布時間:2018-03-14 07:45
本文選題:Dieulafoy病 切入點:臨床特征 出處:《中國內(nèi)鏡雜志》2017年04期 論文類型:期刊論文
【摘要】:目的 Dieulafoy病是一種較少見的上消化道出血性疾病,該研究目的是認(rèn)識胃Dieulafoy病臨床特點及Dieulafoy病經(jīng)治療后再次出血的風(fēng)險因素。方法回顧性研究2009年1月-2016年6月于南昌大學(xué)第一附屬醫(yī)院消化內(nèi)鏡中心經(jīng)胃鏡確診為胃Dieulafoy病出血患者,分析患者的臨床資料、內(nèi)鏡下特點及再出血危險因素。結(jié)果在111例患者中,男97例(87.4%);發(fā)病部位主要好發(fā)于胃底及高位胃體53例(47.7%),按Forrest分級主要為Ⅰ期52例(46.8%)及Ⅱ期58例(52.3%);主要以內(nèi)鏡聯(lián)合藥物治療為主101例(91.0%),內(nèi)鏡治療方法止血成功率為84.2%,單種內(nèi)鏡、兩種內(nèi)鏡、三種內(nèi)鏡治療方法的止血率分別為85.0%、84.8%、75.0%。對于101例行內(nèi)鏡聯(lián)合藥物治療患者,胃底及高位胃體、中低位胃體、胃竇的止血成功率分別為83.7%、82.1%、88.9%。在111例上述觀察指標(biāo)中,年齡(P=0.002)和輸血(P=0.004)在單因素分析中是再出血危險因素;在101例均已行內(nèi)鏡處理的Dieulafoy病出血的患者中,Logistic回歸多因素分析,表明輸血(P=0.018,OR=37.77,95%CI=1.86~766.47)為經(jīng)治療后再出血獨立的危險因素。結(jié)論內(nèi)鏡治療是一種有效的治療方法,輸血為經(jīng)治療后再出血獨立的危險因素,各種內(nèi)鏡治療方法無明顯差異,出血部位不同在經(jīng)治療后再出血組與非再出血組間無明顯差異。
[Abstract]:Objective Dieulafoy's disease is a rare hemorrhagic disease of upper digestive tract. The aim of this study was to understand the clinical features of gastric Dieulafoy's disease and the risk factors for rebleeding after treatment for Dieulafoy's disease. Methods A retrospective study was conducted from January 2009 to June 2016 in the endoscopy Center of Digestive Endoscopy, first affiliated Hospital of Nanchang University. Bleeding patients with gastric Dieulafoy's disease, The clinical data, endoscopic features and risk factors of rebleeding were analyzed. The main sites of the disease were 47.7% in the stomach fundus and 53 cases in the high stomach body, according to the Forrest classification, 52 cases had stage 鈪,
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