本文選題：重癥急性胰腺炎　切入點：肺部感染　出處：《遼寧中醫(yī)雜志》2017年08期 　論文類型：期刊論文

【摘要】：目的:探討血液學(xué)指標在預(yù)測重癥急性胰腺炎合并肺部感染的臨床診斷價值。方法:選擇2013年1月—2015年6月在本院接受治療的重癥急性胰腺炎患者作為研究對象,依據(jù)患者是否伴有肺部感染將患者分為非感染組及感染組。檢測對比兩組外周血TNF-α、IL-10、CRP及降鈣素原水平。結(jié)果:本研究共納入非感染組48例;感染組45例。感染組患者的TNF-α、CRP、降鈣素原均高于非感染組患者,差異具有統(tǒng)計學(xué)意義(P0.05)。ROC曲線分析顯示,以21.44 ng/L為截點值,TNF-α診斷重癥急性胰腺炎繼發(fā)肺部感染的敏感性為80.00%,特異性為85.42%,曲線下面積為0.83;其結(jié)果優(yōu)于CRP、降鈣素原。結(jié)論:TNF-α、CRP、降鈣素原是重癥急性胰腺炎合并肺部感染中的診斷的可靠指標,其中TNF-α具有較高的特異性和敏感性,在預(yù)測重癥急性胰腺炎合并肺部感染具有重要價值。
[Abstract]:Objective: to investigate the clinical diagnostic value of hematologic markers in predicting severe acute pancreatitis complicated with pulmonary infection. Methods: patients with severe acute pancreatitis who were treated in our hospital from January 2013 to June 2015 were selected as study objects. The patients were divided into non-infection group and infected group according to whether the patients were accompanied with pulmonary infection. The levels of TNF- 偽 IL-10 CRP and procalcitonin in peripheral blood were measured and compared between the two groups. Results: 48 cases of non-infection group were included in this study. The TNF- 偽 CRP and procalcitonin levels in the infected group were significantly higher than those in the non-infected group, and the difference was statistically significant. Using 21.44 ng/L as the cut-off point, the sensitivity of TNF- 偽 in the diagnosis of pulmonary infection secondary to severe acute pancreatitis was 80.00g, the specificity was 85.42, and the area under the curve was 0.83.The results were superior to that of CRP- 偽 and procalcitonin. Conclusion: TNF- 偽 is a severe acute pancreatitis complicated with pulmonary infection. Reliable indicators for diagnosis of partial infections, Among them, TNF- 偽 has high specificity and sensitivity, and has important value in predicting severe acute pancreatitis complicated with pulmonary infection.
【作者單位】： 昆明醫(yī)科大學(xué)第一附屬醫(yī)院;
【分類號】：R563.1;R576

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