本文選題：OMOM膠囊內(nèi)鏡　切入點：小腸疾病　出處：《寧夏醫(yī)科大學(xué)》2014年碩士論文　論文類型：學(xué)位論文

【摘要】：目的： 探討OMOM膠囊內(nèi)鏡對消化道疾病，尤其是小腸疾病的診斷價值及安全性，便于臨床合理應(yīng)用。 方法： 回顧性分析2009年9月-2013年12月在寧夏醫(yī)科大學(xué)總醫(yī)院消化內(nèi)科行OMOM膠囊內(nèi)鏡檢查的86例患者(包括不明原因消化道出血患者34例，不明原因腹痛、腹瀉、腹脹及消瘦患者52例)的臨床資料，對診斷結(jié)果進(jìn)行相關(guān)統(tǒng)計學(xué)分析。 結(jié)果： 1、膠囊內(nèi)鏡檢出結(jié)果：86例患者均順利完成檢查，檢查成功率100%（86/86）；共發(fā)現(xiàn)病變81例，病變總檢出率為94.2%（81/86），有68例患者檢出小腸病變，小腸疾病病變檢出率79.1%(68/86)，其中OGIB組小腸病變檢出率為91.2%，最常見的病變?yōu)樾∧c血管畸形，腹痛組小腸病變檢出率為71.2%，病變以小腸炎最為多見，OMOM膠囊內(nèi)鏡也可以檢出消化道系統(tǒng)（如食管、胃、結(jié)腸等）其他病變。老年和中青年患者小腸疾病檢出率無明顯差異（P=0.271），但CE對不明原因的消化道出血患者的小腸病變檢出率明顯高于腹痛組患者（P0.05）。在對OGIB患者經(jīng)CE檢查的時間窗進(jìn)行對比后，出血停止2周內(nèi)經(jīng)CE檢查患者的小腸疾病檢出率與2周以上患者的小腸疾病檢出率無顯著性差異（P0.05）。腸道準(zhǔn)備時肌注甲氧氯普胺（胃復(fù)安）可以促進(jìn)膠囊通過幽門(P=0.028)，從而提高全小腸檢查率，而對小腸運行時間無顯著影響。 2、膠囊運行時間：膠囊在胃內(nèi)運行時間為1.3min-333min，平均運行時間為42.50min（M），在小腸內(nèi)運行時間47min-566min，平均運行時間為284.00min（M）。 3、膠囊內(nèi)鏡檢查的安全性及可靠性：OMOM膠囊內(nèi)鏡性能穩(wěn)定，圖像清晰，，攝像膠囊所攜帶的電池一般能滿足對全小腸的觀察。所有患者無一例出現(xiàn)膠囊滯留，且均未出現(xiàn)其他不良反應(yīng)。 結(jié)論： OMOM膠囊內(nèi)鏡檢查安全、有效，對消化道疾病，特別是小腸疾病有良好的診斷價值，尤其適用于不明原因消化道出血的患者。
[Abstract]:Objective:. To investigate the diagnostic value and safety of OMOM capsule endoscopy for digestive tract diseases, especially small intestinal diseases, and to facilitate its clinical and rational application. Methods:. From September 2009 to December 2013, 86 patients (including 34 patients with unknown gastrointestinal bleeding, unknown abdominal pain and diarrhea) who were examined by OMOM capsule endoscopy in the Department of Digestive Medicine, Ningxia Medical University General Hospital, were retrospectively analyzed. The clinical data of 52 patients with abdominal distension and wasting were analyzed statistically. Results:. 1. The results of capsule endoscopy were as follows: 86 cases of patients were successfully completed, and the success rate was 100% 86%. 81 cases of lesions were found, the total detection rate of lesions was 94.2% 81 / 86%, 68 cases of small bowel lesions were detected. The detection rate of small intestinal diseases was 79.1% / 86%, and the detection rate of small intestinal lesions in OGIB group was 91.2%. The most common lesions were small intestinal vascular malformations. In the abdominal pain group, the detection rate of intestinal lesions was 71.2%. The most common lesions were small enteritis. OMOM capsule endoscopy could also detect gastrointestinal system (such as esophagus, stomach, stomach). There was no significant difference in the detection rate of intestinal diseases between aged and young patients, but the detection rate of intestinal lesions in patients with unknown gastrointestinal bleeding was significantly higher than that in patients with abdominal pain (P 0.05). In OGIB patients with CE, the detection rate of intestinal diseases was significantly higher than that of patients with abdominal pain. After comparing the time window of the inspection, There was no significant difference between the detection rate of intestinal diseases in patients with CE examination and those of patients over 2 weeks after bleeding cessation (P 0.05). Intramuscular injection of metoclopramide (metoclopramide) during intestinal preparation could promote capsule passage through pylorus. In order to improve the examination rate of the whole small intestine, However, there was no significant effect on the operation time of small intestine. 2, the running time of capsule: the running time of capsule in stomach was 1.3min-333min, the average running time was 42.50min, the running time in small intestine was 47min-566min, the average time was 284.00min. 3. The safety and reliability of the capsule endoscopy were stable, the images were clear, the battery carried by the camera capsule could generally satisfy the observation of the whole small intestine. None of the patients had capsule retention. There were no other adverse reactions. Conclusion:. OMOM capsule endoscopy is safe and effective, and has good diagnostic value for gastrointestinal diseases, especially small intestinal diseases, especially for patients with unknown gastrointestinal bleeding.
【學(xué)位授予單位】：寧夏醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R574

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 趙曉晏;王雷;樊超強;李宜輝;郭紅;田小溪;李春花;;國產(chǎn)OMOM膠囊內(nèi)鏡臨床應(yīng)用研究[J];第三軍醫(yī)大學(xué)學(xué)報;2007年19期

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