【摘要】：目的觀察在藥物治療基礎上的心理干預對持續(xù)性中-重度變應性鼻炎的治療效果如何。方法將符合入選標準的60例持續(xù)性中-重度變應性鼻炎患者隨機分為對照組、研究組共2組,對照組僅給予單純藥物治療,研究組在給予與對照組相同藥物治療的基礎上,加以心理干預,心理干預選用認知行為療法,以上兩組均治療12周,并于治療前、治療后均采用SAS、SDS、RQLQ三項量表評分,以評估患者治療前后的焦慮、抑郁狀態(tài),以及生活質(zhì)量變化并進行統(tǒng)計學分析。結果對照組治療后SAS、SDS評分(50.57±3.64、52.77±5.11)均分別低于治療前(55.63±5.42、59.57±6.23),差異具有統(tǒng)計學意義(P0.05)。研究組治療后SAS、SDS評分(45.83±3.97、46.03±3.21)均分別低于治療前(56.20±3.81、58.53±5.16),差異具有統(tǒng)計學意義(P0.05)。且研究組治療后SAS、SDS評分(45.83±3.97、46.03±3.21)較對照組(50.57±3.64、52.77±5.11)更低,差異具有統(tǒng)計學意義(P0.05)。對照組治療后RQLQ各維度評分(7.13±1.28、3.77±0.90、15.90±1.69、5.43±1.94、7.03±1.35、6.03±1.35、7.10±1.09)均分別低于治療前(11.97±1.54、6.73±1.34、24.30±2.55、10.83±1.91、13.93±2.13、9.77±1.70、11.20±2.06),差異具有統(tǒng)計學意義(P0.05)。研究組治療后RQLQ各維度評分(6.67±1.45、2.87±0.78、12.47±1.63、5.80±1.09、6.43±1.13、5.70±1.15、5.73±1.46)均分別低于治療前(11.93±1.28、7.03±1.30、23.73±2.70、11.23±2.14、14.53±2.30、9.33±1.56、11.37±1.88),差異具有統(tǒng)計學意義(P0.05)。經(jīng)兩種不同方案治療后,在睡眠、非鼻/眼癥狀、情感3個維度評分中,研究組(2.87±0.78、12.47±1.63、5.73±1.46)均低于對照組(3.77±0.90、15.90±1.69、7.10±1.09),差異具有統(tǒng)計學意義(P0.05)。而研究組的日常生活、實際問題、鼻部癥狀、眼部癥狀4個維度評分(6.67±1.45、5.80±1.09、6.43±1.13、5.70±1.15)與對照組(7.13±1.28、5.43±1.94、7.03±1.35、6.03±1.35)的差異無統(tǒng)計學意義(P0.05)。結論1、藥物治療、藥物治療加以心理干預這兩種治療方案均能減輕持續(xù)性中-重度AR患者的焦慮、抑郁狀態(tài),改善其生活質(zhì)量。2、從改善持續(xù)性中-重度AR患者的精神心理紊亂以及生活質(zhì)量的療效看來,在藥物治療的基礎上加以心理干預優(yōu)于單純使用藥物治療。
[Abstract]:Objective to observe the therapeutic effect of psychological intervention on persistent moderate to severe allergic rhinitis. Methods Sixty patients with persistent moderate to severe allergic rhinitis were randomly divided into control group and control group. The control group was only given simple drug treatment. The study group was given psychological intervention on the basis of the same drug treatment as the control group, and cognitive behavioral therapy was used for psychological intervention. Both groups were treated for 12 weeks, and all of them were scored by SAS,SDS,RQLQ before and after treatment. The changes of anxiety, depression and quality of life before and after treatment were evaluated and statistically analyzed. Results after treatment, the SAS,SDS scores of the control group (50.57 鹵3.64, 52.77 鹵5.11) were significantly lower than those before treatment (5563 鹵5.42, 59.57 鹵6.23), and the difference was statistically significant (P 0.05). The SAS,SDS scores of the study group after treatment (45.83 鹵3.97, 46.03 鹵3.21) were lower than those before treatment (56.20 鹵3.81, 58.53 鹵5.16), the difference was statistically significant (P 0.05). The SAS,SDS score of the study group (45.83 鹵3.97, 46.03 鹵3.21) was lower than that of the control group (50.57 鹵3.64, 52.77 鹵5.11), the difference was statistically significant (P 0.05). After treatment, the scores of RQLQ in the control group (7.13 鹵1.28, 3.77 鹵0.90, 15.90 鹵1.69, 5.43 鹵1.94, 7.03 鹵1.35, 6.03 鹵1.35, 7.10 鹵1.09) were significantly lower than those before treatment (11.97 鹵1.54, 6.73 鹵1.34, 10.83 鹵1.91, 13.93 鹵2.13, 9.77 鹵1.70, 11.20 鹵2.06). After treatment, the scores of RQLQ in the study group (6.67 鹵1.45,2.87 鹵0.78, 12.47 鹵1.63, 5.80 鹵1.09, 6.43 鹵1.13, 5.70 鹵1.15, 5.73 鹵1.46) were significantly lower than those before treatment (11.93 鹵1.28, 7.03 鹵1.30, 23.73 鹵2.70, 11.23 鹵2.14, 14.53 鹵2.30, 9.33 鹵1.56, 11.37 鹵1.88). After treatment with two different regimens, the scores of sleep, non-nasal / eye symptoms and emotion in the study group (2.87 鹵0.78, 12.47 鹵1.63, 5.73 鹵1.46) were significantly lower than those in the control group (3.77 鹵0.90, 15.90 鹵1.69, 7.10 鹵1.09) (P 0.05). However, there was no significant difference in daily life, practical problems, nasal symptoms and eye symptoms between the study group and the control group (6.67 鹵1.45, 5.80 鹵1.09, 6.43 鹵1.13, 5.70 鹵1.15) and the control group (7.13 鹵1.28, 5.43 鹵1.94, 7.03 鹵1.35, 6.03 鹵1.35) (P 0.05). Conclusion 1. Drug therapy with psychological intervention can reduce anxiety, depression and improve the quality of life of patients with persistent moderate to severe AR. 2. From the point of view of improving the mental and psychological disorder and quality of life of patients with persistent moderate to severe AR, psychological intervention on the basis of drug treatment is superior to drug therapy alone.
【學位授予單位】：寧夏醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R765.21

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