90例鼻咽癌調(diào)強(qiáng)放療不良反應(yīng)的臨床觀察
發(fā)布時間:2019-05-18 20:47
【摘要】:目的:觀察鼻咽癌調(diào)強(qiáng)放療的急性反應(yīng)和慢性損傷。方法:將鼻咽癌患者90例,全程調(diào)強(qiáng)放療,總劑量71.4~74.2 Gy。根據(jù)RTOG/EORTC標(biāo)準(zhǔn),對其不良反應(yīng)進(jìn)行評估。結(jié)果:中位隨訪時間38個月,1年、2年、3年總生存率分別為96.7%、93.3%和87.8%,無遠(yuǎn)處轉(zhuǎn)移生存率分別為92.2%、91.1%和85.6%,局部/區(qū)域控制率分別為97.8%、94.4%和88.9%。最嚴(yán)重的急性毒副反應(yīng)是放射性黏膜炎,Ⅰ~Ⅳ級分別為12.2%、47.8%、37.8%和2.2%。晚期毒副反應(yīng)主要表現(xiàn)為口干,Ⅰ級31.1%,Ⅱ期7.7%,Ⅲ期3.3%。結(jié)論:鼻咽癌調(diào)強(qiáng)放療雖然腫瘤劑量高,但周圍正常組織劑量低,故不良反應(yīng)較輕。
[Abstract]:Objective: to observe the acute response and chronic injury of intensity modulation radiotherapy for nasopharyngeal carcinoma (NPC). Methods: 90 patients with nasopharyngeal carcinoma were treated with intensity modulation radiotherapy with a total dose of 71.4 鈮,
本文編號:2480324
[Abstract]:Objective: to observe the acute response and chronic injury of intensity modulation radiotherapy for nasopharyngeal carcinoma (NPC). Methods: 90 patients with nasopharyngeal carcinoma were treated with intensity modulation radiotherapy with a total dose of 71.4 鈮,
本文編號:2480324
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