【摘要】：目的通過觀察突發(fā)性聾伴眩暈患者前庭誘發(fā)肌源性電位的引出率及各參數(shù),探討前庭誘發(fā)肌源性電位對突聾伴眩暈患者內(nèi)耳損傷情況的診斷及預(yù)后評估。方法收集50例單耳突聾伴眩暈的患者,50例單耳突聾不伴眩暈患者及60例正常聽力人作為對照組,分析對比o VEMP及c VEMP的引出率和各參數(shù)變化。結(jié)果引出率:病例組患耳、對側(cè)耳、突聾不伴眩暈組及正常對照組o VEMP引出率分別為24%、42%、48%、100%,c VEMP引出率分別為:56%、74%、64%、100%,病例組患耳和對側(cè)耳相比,o VEMP及c VEMP引出率差異無統(tǒng)計學(xué)意義(P0.05),病例組患耳及對側(cè)耳分別和正常對照組比較,o VEMP及c VEMP引出率均明顯降低(P0.05),病例組患耳o VEMP引出率明顯低于突聾不伴眩暈組(P0.05)。o VEMP:病例組患耳、對側(cè)耳、突聾不伴眩暈組及正常對照組的各參數(shù)(N1潛伏期、P1潛伏期、P1-N1振幅)兩兩比較,組間不對稱比(AR)比較,差異均無統(tǒng)計學(xué)意義(P均0.05)。c VEMP:病例組患耳、對側(cè)耳、突聾不伴眩暈組及正常對照組的各參數(shù)比較,患耳及對側(cè)耳P1-N1振幅比突聾不伴眩暈組及正常對照組均明顯降低(P0.05),病例組AR比正常對照組明顯增高(P0.05),o VEMP及c VEMP結(jié)果與聽力損失分型、聽力損失程度分級無明顯相關(guān)性(P0.05),但與療效分級明顯相關(guān)(P0.05)。結(jié)論突聾伴眩暈患者存在同側(cè)及對側(cè)的橢圓囊(前庭上神經(jīng))和球囊(前庭下神經(jīng))傳導(dǎo)功能障礙,前庭誘發(fā)肌源性電位為突聾伴眩暈患者耳石器及前庭神經(jīng)功能評估提供客觀依據(jù)。
[Abstract]:Objective to observe the evoked rate and parameters of vestibular evoked myogenic potentials in patients with sudden deafness with vertigo, and to explore the diagnosis and prognosis of vestibular evoked myogenic potentials in patients with sudden deafness with vertigo. Methods 50 patients with mono-auricular deafness with vertigo, 50 patients with simple aural deafness without vertigo and 60 normal hearing subjects were collected as the control group. The induced rates and parameters of o-VEMP and c-VEMP were analyzed and compared. Results the induced rate of VEMP was 24%, 42%, 48%, 100% in case group, contralateral ear, sudden deafness without vertigo and normal control group, respectively. The induced rate of c-VEMP was 56%, 74%, 64%, 100%, respectively. There was no significant difference in the induced rate of, o VEMP and c-VEMP between the case group and the contralateral ear (P0.05). The incidence rate of, o VEMP and c-VEMP in the case group and the contralateral ear was significantly lower than that in the normal control group (P0.05). The induced rate of o-VEMP in the case group was significantly lower than that in the sudden deafness without vertigo group (P0.05) (P05 -). O VEMP: case group, contralateral ear, sudden deafness without vertigo group and normal control group) (N1 latency, P1 latency, P _ 1 latency). There was no significant difference in P1-N1 amplitude between the two groups, and there was no significant difference in the asymmetrical ratio between the two groups (P0.05). C VEMP: group, the contralateral ear, the deafness without vertigo group and the normal control group). The amplitude of P1-N1 in the affected ears and contralateral ears was significantly lower than that in the deafness without vertigo group and the normal control group (P0.05), and the AR in the patient group was significantly higher than that in the normal control group (P0.05), o VEMP and c VEMP results and hearing loss classification). There was no significant correlation between the grade of hearing loss (P0.05), but it was significantly correlated with the grade of therapeutic effect (P0.05). Conclusion there are ipsilateral and contralateral ellipsoidal (superior vestibular nerve) and balloon (inferior vestibular nerve) conduction dysfunction in patients with synaptic deafness with vertigo. Vestibular evoked myogenic potential provides objective basis for evaluation of otolith and vestibular nerve function in patients with sudden deafness with vertigo.
【作者單位】： 唐山市協(xié)和醫(yī)院耳鼻咽喉頭頸外科;華北理工大學(xué)附屬醫(yī)院血管外科;河北醫(yī)科大學(xué)第二醫(yī)院耳鼻咽喉科;
【基金】：2017年度河北省醫(yī)學(xué)科學(xué)研究重點課題計劃,項目編號:20171308~~
【分類號】：R764

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