放療劑量對鼻咽癌患者QT離散度、心率變異性時(shí)域、頻域及心電圖的影響
[Abstract]:Objective to investigate the effects of different radiation doses on QT dispersion, time domain and frequency domain parameters of heart rate variability (HRV) and electrocardiogram (ECG) in patients with nasopharyngeal carcinoma (NPC). Methods Seventy-three patients with nasopharyngeal carcinoma received radiotherapy at doses of 15? 25,35? 45, 55? 65 Gy. The mean standard deviation (SDANN),) of (QTcd), NN interval standard deviation (QTcd), NN interval) after correction of QT dispersion (QTd), before and after radiotherapy was observed before and after radiotherapy. The mean (SDNN), NN interval standard deviation of (QTcd), NN interval was observed before and after radiotherapy. The root mean square of the mean value of adjacent NN intervals (the percentage of beats with r-MSSD,NN interval difference more than 50 ms) (p-NN50); Frequency domain index: very low frequency power (VLF), low frequency power (LF), high frequency power (HF), LF/HF, total power (TP), etc. Results compared with pre-treatment, the SDNN,r MSSD,p NN50,TP,VLF,LF,HF of patients treated with 15, 35, 55 Gy decreased, and decreased with the increase of radiation dose (P0.05). The incidence of sinus arrhythmias was significantly lower than that before radiotherapy (P0.05). Conclusion the changes of cardiac autonomic nerve function in patients with nasopharyngeal carcinoma can be closely monitored by monitoring the time-domain and frequency-domain parameters of QTd,QTcd,HRV in the course of radiotherapy, which can provide a certain basis for the evaluation of radiotherapy and prognosis.
【作者單位】: 廣西壯族自治區(qū)人民醫(yī)院;
【基金】:廣西壯族自治區(qū)衛(wèi)生廳自籌經(jīng)費(fèi)科研課題(編號:Z2011428)
【分類號】:R739.63
【相似文獻(xiàn)】
相關(guān)期刊論文 前8條
1 王守巖,菅忠,張立藩,牛有國;健康人心率變異性中的不穩(wěn)定周期軌道[J];中華航空航天醫(yī)學(xué)雜志;2000年04期
2 熊萍;連捷;;惡性腫瘤患者的心率變異性臨床初探[J];實(shí)用醫(yī)技雜志;2006年01期
3 余婷,劉阿力,王忠誠,馮偉捷;延髓腫瘤心電圖QT離散度觀察[J];中國急救醫(yī)學(xué);2002年10期
4 郭惠玲,李京英,王蓉;221例腫瘤患者術(shù)前QT離散度分析[J];實(shí)用心電學(xué)雜志;2003年03期
5 陳兆華,陸惠芳,吳曄良;32例肺癌患者心肌缺血時(shí)QT離散度分析[J];實(shí)用心電學(xué)雜志;2001年01期
6 陳晨;劉海媛;;不同分期惡性腫瘤患者的心率變異性分析[J];復(fù)旦學(xué)報(bào)(醫(yī)學(xué)版);2009年04期
7 張琴;張雅莉;何寧;陸錦龍;田曉芬;陳曉婕;吳潔;李玲;秦國偉;;鼻咽癌患者放射治療后動態(tài)心電圖及QT離散度和心率變異性改變的探討[J];江蘇實(shí)用心電學(xué)雜志;2014年04期
8 郭惠玲,席昕;140例不同部位腫瘤ST-T改變、QT離散度及術(shù)后心律失常[J];實(shí)用心電學(xué)雜志;2005年03期
相關(guān)碩士學(xué)位論文 前1條
1 陳靜珊;鼻咽癌患者鼻咽部菌群結(jié)構(gòu)特點(diǎn)及其在放療過程中的動態(tài)變化[D];廣西醫(yī)科大學(xué);2016年
,本文編號:2446642
本文鏈接:http://sikaile.net/yixuelunwen/wuguanyixuelunwen/2446642.html