【摘要】：目的探討倒頻譜聲學(xué)分析法與連貫言語聲學(xué)信號用于鑒別病理性聲信號的價值。方法分別采集26例成人聲帶息肉患者(息肉組,男10例,女16例)及27例正常嗓音者(正常組,男13例,女14例)持續(xù)元音和連貫言語聲信號,采用MDVP(multi dimensional voice program)軟件分析各組持續(xù)元音頻率微擾(jitter)和振幅微擾(shimmer),采用ADSV(analysis of dysphonia in speech and voice)軟件分析各組持續(xù)元音和連貫言語的倒頻譜參數(shù):倒頻譜峰值突出(cepstral peak prominence,CPP)、低高頻譜能量比(the mean ratio of singnal energy below 4000Hz to the energy above 4 000Hz,L/HSR)、CPP的標(biāo)準(zhǔn)差(STD CPP)、L/HSR的標(biāo)準(zhǔn)差(STD L/HSR)及發(fā)音障礙倒頻譜指數(shù)(the cepstral/spectral index of dysphonia,CSID),分析擾動參數(shù)和倒頻譜參數(shù)對鑒別病理聲學(xué)信號的敏感性。結(jié)果正常組持續(xù)元音的jitter和shimmer值均小于聲帶息肉組(P0.05);除STD L/HSR外,正常組持續(xù)元音的倒頻譜參數(shù)值均高于息肉組(P0.05);連貫言語的倒頻譜參數(shù)中,男性聲帶息肉組的CPP、L/HSR均低于男性正常組(P0.05),女性聲帶息肉組CPP值明顯低于女性正常組(P0.05)。男女性持續(xù)元音聲信號的倒頻譜參數(shù)CPP和CSID在ROC曲線下的面積與參考值0.5相比,差異有統(tǒng)計學(xué)意義(P0.05);男性連貫言語聲的CPP及L/HSR、女性CPP ROC曲線下的面積與參考值0.5的差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論連貫言語聲和持續(xù)元音的擾動參數(shù)和倒頻譜參數(shù)均可用于區(qū)別正常與聲帶息肉患者的噪音聲學(xué)信號,倒頻譜參數(shù)CPP對區(qū)別正常和聲帶息肉患者嗓音信號有較好的特異度和靈敏度。
[Abstract]:Objective to explore the value of cepstrum acoustic analysis and coherent speech acoustic signals in the identification of pathological acoustic signals. Methods persistent vowels and coherent speech signals were collected in 26 adult patients with polyp of vocal cord (polyp group, 10 males, 16 females) and 27 normal speakers (normal group, 13 males and 14 females). Analysis of continuous vowel frequency perturbed (jitter) and amplitude perturbed (shimmer), in each group by MDVP (multi dimensional voice program) software The cepstrum parameters of continuous vowel and coherent speech in each group were analyzed by ADSV (analysis of dysphonia in speech and voice) software: cepstrum peak prominent (cepstral peak prominence,CPP, low spectral energy ratio (the mean ratio of singnal energy below 4000Hz to the energy above 4000Hz, L/HSR). The standard deviation (STD L/HSR) of (STD CPP), L/HSR and the cepstrum index (the cepstral/spectral index of dysphonia,CSID) of CPP were used to analyze the sensitivity of disturbance parameters and cepstrum parameters to differential diagnosis of pathological acoustic signals. Results the jitter and shimmer values of the continuous vowels in the normal group were lower than those in the vocal cord polyp group (P0.05), except for STD L/HSR, the Cepstrum parameters of the continuous vowels in the normal group were higher than those in the polyp group (P0.05). The CPP,L/HSR of male vocal cord polyp group was lower than that of male normal group (P0.05), and the CPP value of female vocal cord polyp group was significantly lower than that of female normal group (P0.05). The Cepstral parameters (CPP and CSID) of male and female persistent vowels were significantly different from the reference value (P0.05) under the ROC curve. There was a significant difference between the area under the CPP ROC curve and the reference value of CPP and L-HSR in male coherent speech sounds (P0.05). Conclusion the perturbed parameters and cepstrum parameters of continuous vowels and continuous vowels can be used to distinguish the noise acoustic signals between normal and vocal cord polyp patients. The cepstrum parameter CPP has good specificity and sensitivity in distinguishing vocal signal between normal and vocal cord polyps.
【作者單位】： 廈門大學(xué)附屬中山醫(yī)院耳鼻咽喉科;廈門大學(xué);
【基金】：國家自然科學(xué)基金(NSFC81371080) 福建省衛(wèi)生系統(tǒng)中青年骨干人才培養(yǎng)項目(2013-ZQN-JC-35)聯(lián)合資助
【分類號】：R767.92

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