【摘要】：目的探討年齡相關(guān)性白內(nèi)障患者眼軸長(zhǎng)度與角膜曲率、角膜散光、前房深度和眼壓的關(guān)系。方法本次研究對(duì)象為在武漢大學(xué)中南醫(yī)院行白內(nèi)障手術(shù)的年齡相關(guān)性白內(nèi)障患者368例(368眼)�；颊叩难圯S長(zhǎng)度、角膜曲率、角膜散光和前房深度均應(yīng)用IOL-Master(德國(guó)蔡司公司)進(jìn)行測(cè)量,眼壓采用i Care眼壓計(jì)測(cè)量。使用隨機(jī)抽樣法從不同眼軸長(zhǎng)度患者中隨機(jī)抽出80例(80眼),分別為短眼軸組、中眼軸組和長(zhǎng)眼軸組。各組間比較采用單因素方差分析。眼軸長(zhǎng)度和角膜曲率、角膜散光、前房深度及眼壓的關(guān)系采用Spearman相關(guān)分析。結(jié)果眼軸長(zhǎng)度與角膜曲率(r=-0.424,P0.001)、眼軸長(zhǎng)度與角膜散光(r=0.138,P=0.008)、眼軸長(zhǎng)度與前房深度(r=0.561,P0.001)均相關(guān)。其中,眼軸長(zhǎng)度與角膜曲率呈負(fù)相關(guān),與角膜散光和前房深度呈正相關(guān),但與角膜散光相關(guān)性較弱,而與角膜曲率和前房深度中度相關(guān)。眼軸長(zhǎng)度與眼壓無(wú)相關(guān)性(r=0.064,P=0.326)。中眼軸組和長(zhǎng)眼軸組角膜曲率與短眼軸組比較,差異均有統(tǒng)計(jì)學(xué)意義(均為P0.001);而中眼軸組與長(zhǎng)眼軸組差異無(wú)統(tǒng)計(jì)學(xué)意義(P=0.438)。中眼軸組與短眼軸組的角膜散光差異無(wú)統(tǒng)計(jì)學(xué)意義(P=0.333),同樣中眼軸組與長(zhǎng)眼軸組的角膜散光差異亦無(wú)統(tǒng)計(jì)學(xué)意義(P=0.718),但是短眼軸組與長(zhǎng)眼軸組的角膜散光差異有統(tǒng)計(jì)學(xué)意義(P=0.042)。短眼軸組的前房深度與中眼軸組(P=0.001)和長(zhǎng)眼軸組(P0.001)比較差異均有統(tǒng)計(jì)學(xué)意義,中眼軸組與長(zhǎng)眼軸組的前房深度差異亦有統(tǒng)計(jì)學(xué)意義(P0.001)。3組眼壓兩兩比較差異均無(wú)統(tǒng)計(jì)學(xué)意義(均為P0.05)。結(jié)論角膜曲率與眼軸長(zhǎng)度呈負(fù)相關(guān);角膜散光與眼軸長(zhǎng)度相關(guān)性弱,只有眼軸長(zhǎng)度明顯增長(zhǎng),才有可能表現(xiàn)出角膜散光度數(shù)增加;前房深度與眼軸長(zhǎng)度中等相關(guān),并隨眼軸增長(zhǎng)而加深;眼軸長(zhǎng)度與眼壓無(wú)相關(guān)性。
[Abstract]:Objective to investigate the relationship between axial length and corneal curvature, corneal astigmatism, anterior chamber depth and intraocular pressure in patients with age-related cataract. Methods 368 patients (368 eyes) with age-related cataract underwent cataract surgery in Central and Southern Hospital of Wuhan University. The axial length, corneal curvature, corneal astigmatism and anterior chamber depth were measured by IOL-Master and I Care IOP. Eighty patients (80 eyes) with different axial lengths were randomly selected by random sampling. They were short axis group, middle axis group and long eye axis group. Single factor analysis of variance was used for comparison among groups. The relationship between axial length and corneal curvature, corneal astigmatism, anterior chamber depth and intraocular pressure was analyzed by Spearman correlation. Results the length of eye axis was correlated with corneal curvature (r = 0.424), corneal astigmatism (r ~ (0.138) P ~ (0.008) and anterior chamber depth (r ~ (0.561) P ~ (0.001). Among them, the length of eye axis was negatively correlated with corneal curvature, positively correlated with corneal astigmatism and anterior chamber depth, but weakly correlated with corneal astigmatism, but moderately correlated with corneal curvature and anterior chamber depth. There was no correlation between axial length and intraocular pressure (r = 0.064). There were significant differences in corneal curvature between the middle axis group and the long axis group compared with the short eye axis group (P 0.001), but there was no significant difference between the middle eye axis group and the long eye axis group (P 0. 438). There was no significant difference in corneal astigmatism between the middle axis group and the short axis group (P0. 333), and there was no significant difference in the corneal astigmatism between the middle axis group and the long axis group (P0. 718). But there was significant difference in corneal astigmatism between the short-axis group and the long-axis group (P0. 042). The depth of anterior chamber in the short axis group was significantly different from that in the middle axis group (P0. 001) and the long axis group (P0. 001). There was also significant difference in anterior chamber depth between the middle axis group and the long axial group (P0.001). There was no significant difference in IOP between the 3 groups (P0.05). Conclusion there is a negative correlation between corneal curvature and axial length, and the correlation between corneal astigmatism and axial length is weak, only when the length of ocular axis increases obviously, can the corneal astigmatism degree increase. The depth of anterior chamber was correlated with the length of eye axis and deepened with the increase of eye axis, but there was no correlation between axial length and intraocular pressure.
【作者單位】： 武漢大學(xué)中南醫(yī)院眼科;
【分類(lèi)號(hào)】：R776.1

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