【摘要】：目的建立阻塞性睡眠呼吸暫停低通氣綜合征（OSAHS）患者的上氣道及毗鄰結(jié)構(gòu)三維有限元模型，通過逐步前伸下頜，觀察OSAHS患者舌骨位置的改變及其與下頜前伸量之間的關(guān)系，為下頜前伸類口腔矯治器治療OSAHS的機理研究提供理論依據(jù)。 方法對OSAHS患者上氣道行薄層CT掃描，以DICOM格式輸出數(shù)據(jù)，采用Mimics三維建模軟件和Ansys有限元分析軟件建立上氣道及毗鄰結(jié)構(gòu)的三維有限元模型，然后通過加載下頜骨逐步前伸，觀察舌骨位置的變化及規(guī)律。 結(jié)果建立了OSAHS患者上氣道及毗鄰結(jié)構(gòu)的三維有限元模型，定義采用10節(jié)點的solid92四面體單元劃分網(wǎng)格，按要求劃分網(wǎng)格后，，皮質(zhì)骨、松質(zhì)骨、肌肉及氣道各得到的單元數(shù)和節(jié)點數(shù)分別為：562920、50141、336789個單元，544929、84869、303134個節(jié)點。通過逐步前伸下頜骨，舌骨位置向上向前移動， 結(jié)論應(yīng)用螺旋CT技術(shù)聯(lián)合使用Mimics三維建模軟件，Ansys有限元分析軟件建立OSAHS患者上氣道及其毗鄰結(jié)構(gòu)三維有限元模型，模型的幾何相似性較好，使用靈活；通過下頜逐步前伸，對舌骨位置變化進行分析，有效展示下頜骨前伸與舌骨位置變化兩者之間關(guān)系，證實了研究方法的可行性，為下頜前伸矯治器治療OSAHS提供理論依據(jù)，同時為后續(xù)研究OSAHS患者上氣道生物力學分析打下良好的基礎(chǔ)。
[Abstract]:Objective to establish a three-dimensional finite element model of upper airway and adjacent structure in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). To provide a theoretical basis for the study of the mechanism of mandibular protruding oral appliance in the treatment of OSAHS. Methods the upper airway and adjacent structures of patients with OSAHS were scanned by thin slice CT scanning, and the data were outputted in DICOM format. The 3D finite element models of upper airway and adjacent structures were established by Mimics and Ansys software, and then the mandible was gradually extended forward by loading. The changes and rules of hyoid position were observed. Results the three-dimensional finite element model of upper airway and adjacent structure of OSAHS patients was established. The 10-node solid92 tetrahedron element was used to mesh the cortex bone and cancellous bone. The number of units and nodes of muscle and airway were respectively 5449299,848699,303134 nodes. The position of hyoid bone was moved upward through the progressive extension of mandible. Conclusion the 3D finite element model of upper airway and adjacent structure of OSAHS patients was established by using Mimics 3D modeling software and Ansys finite element analysis software. The geometric similarity of the model is good, and it is flexible to use. Through the analysis of the hyoid position change through the mandibular progressive extension, the relationship between the mandibular forward extension and the hyoid position change is effectively demonstrated, which proves the feasibility of the research method. It provides a theoretical basis for the treatment of OSAHS with mandibular extension appliance and lays a good foundation for further study on biomechanical analysis of upper airway in patients with OSAHS.
【學位授予單位】：寧夏醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R766

【參考文獻】

相關(guān)期刊論文 前10條

1 趙雪巖;黃任含;樓航迪;榮起國;;阻塞性睡眠呼吸暫停綜合征的生物力學研究[J];北京大學學報(自然科學版);2009年05期

2 蘇莉,紀昌蓉;骨性安氏Ⅰ、Ⅲ類錯鉭舌骨位置的對比研究[J];北京口腔醫(yī)學;2002年02期

3 賈培增,傅民魁,曾祥龍;下頜前伸對阻塞性睡眠呼吸暫停綜合征患者上氣道形態(tài)的作用[J];北京大學學報(醫(yī)學版);2003年06期

4 王瑩;孫秀珍;劉迎曦;于馳;張軍;于申;;OSAHS患者與正常人上呼吸道流場特性比較[J];大連理工大學學報;2009年04期

5 鄔銘峰;羅濤;王亞敏;郭瑩;唐亮;;三維有限元法在口腔醫(yī)學中的應(yīng)用[J];廣東牙病防治;2007年01期

6 胡寶明,葉京英;女性激素與阻塞性睡眠呼吸暫停低通氣綜合征[J];國外醫(yī)學.耳鼻咽喉科學分冊;2004年05期

7 孫秀珍;于馳;劉迎曦;于申;張軍;蘇英鋒;;人體上呼吸道三維有限元重建與流場數(shù)值模擬[J];航天醫(yī)學與醫(yī)學工程;2006年02期

8 童茂榮,樂瑋,夏錫榮;阻塞性睡眠呼吸暫�；颊呱蠚獾乐車浗M織異常[J];醫(yī)學研究生學報;2000年01期

9 焦培峰;齊向東;祁佐良;方建藺;陸云濤;鐘世鎮(zhèn);原林;;下頜角的CT三維重建模擬整形術(shù)[J];解剖學報;2006年05期

10 于力牛,常偉,王成燾,張富強;基于實體模型的牙頜組織三維有限元建模問題探討[J];機械設(shè)計與研究;2002年02期

相關(guān)碩士學位論文 前2條

1 王麗珍;基于CT掃描之腰椎椎體有限元分析[D];吉林大學;2007年

2 郭克峰;利用Mimics重建上下頜骨和牙列及有限元分析[D];吉林大學;2008年

本文編號：2199116