【摘要】：目的:研究耳蝸畸變產(chǎn)物與基膜調(diào)諧功能關(guān)系。方法:采用激光干涉技術(shù),對18例剛死亡豚鼠在體耳蝸基膜在頻率為1 000Hz和1 400Hz純音激勵下振動的畸變產(chǎn)物及其調(diào)諧曲線隨時間變化進行測量。結(jié)果:觀察到耳蝸基膜振動畸變產(chǎn)物幅度隨時間變化逐漸衰減,直至消失。與之相伴的是基膜調(diào)諧曲線的銳度逐漸鈍化,響應(yīng)幅度逐漸下降。在畸變產(chǎn)物消失后基膜響應(yīng)幅度極度下降,調(diào)諧曲線極度平坦。結(jié)論:基膜振動畸變產(chǎn)物與基膜對聲激勵的響應(yīng)幅度和調(diào)諧銳度有關(guān)聯(lián),基膜振動畸變產(chǎn)物是否存在,反映了耳蝸中影響聽力水平與音調(diào)辨識能力的基膜響應(yīng)幅度增強功能與調(diào)諧銳化功能是否存在并發(fā)揮作用。
[Abstract]:Objective: to study the relationship between cochlear aberration product and basal membrane tuning function. Methods: the distortion products and tuning curves of the basal membrane of the cochlea of 18 newly dead guinea pigs were measured by laser interferometry under pure tone excitation of 1 000Hz and 1 400Hz. Results: the amplitude of vibration distortion product of the basal membrane of cochlea decreased gradually with time until it disappeared. The acuity of the tuning curve of the substrate was passivated and the response amplitude decreased gradually. When the distortion product disappeared, the response amplitude of the substrate was extremely decreased, and the tuning curve was extremely flat. Conclusion: the vibration distortion product of the substrate is related to the amplitude of response to acoustic excitation and the tuning acuity of the substrate, and whether the vibration distortion product of the substrate exists or not. It reflects whether the enhancement function of the base membrane response amplitude and the tuning sharpening function which affect the hearing level and the tone recognition ability in the cochlea exist and play a role.
【作者單位】： 華中科技大學校醫(yī)院;漢川市人民醫(yī)院神經(jīng)外科;華中科技大學物理學院;
【基金】：國家自然科學基金(No:11374118) 湖北省自然科學基金(No:2013CFB280)
【分類號】：R764
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本文編號：2193518