【摘要】：目的總結(jié)3例確診的真菌感染性視神經(jīng)炎患者的臨床特點(diǎn),探討真菌感染性視神經(jīng)炎的診治要點(diǎn)。設(shè)計(jì)回顧性病例。研究對(duì)象3例確診的真菌感染性視神經(jīng)炎患者。方法對(duì)3例真菌感染性視神經(jīng)炎患者的癥狀、體征、影像學(xué)檢查進(jìn)行總結(jié),分析歸納真菌感染性視神經(jīng)炎的臨床特點(diǎn)及診斷要點(diǎn)。主要指標(biāo)臨床癥狀、體征,影像學(xué)特點(diǎn),病理結(jié)果。結(jié)果 3例真菌感染性視神經(jīng)炎患者均為中老年男性,單眼或雙眼先后發(fā)病。合并有系統(tǒng)性疾病。臨床表現(xiàn)為急性嚴(yán)重的視力下降,伴頭痛、眼痛、眼脹,可伴有眼瞼下垂和眼球運(yùn)動(dòng)障礙。CT表現(xiàn)為軟組織密度影,眼眶側(cè)壁骨質(zhì)吸收。眼眶磁共振(MRI)異常信號(hào)伴不規(guī)則強(qiáng)化,邊界不清。組織病理見菌絲孢子和真菌團(tuán)。經(jīng)手術(shù)清除病灶及全身長(zhǎng)期抗真菌治療后癥狀好轉(zhuǎn),病情穩(wěn)定。結(jié)論急劇的單側(cè)視力下降伴頭痛、眼球脹痛,應(yīng)考慮到真菌感染的可能。影像學(xué)檢查輔助診斷,病理活檢為診斷金標(biāo)準(zhǔn)。應(yīng)及時(shí)手術(shù)清除病灶及全身長(zhǎng)期抗真菌治療。
[Abstract]:Objective to summarize the clinical features of 3 cases of fungal infective optic neuritis and discuss the main points of diagnosis and treatment of fungal infective optic neuritis. Design retrospective cases. Participants three patients with fungal infective optic neuritis were studied. Methods the symptoms, signs and imaging findings of 3 patients with fungal infective optic neuritis were summarized, and the clinical features and diagnostic points of fungal infective optic neuritis were analyzed and summarized. Main outcome measures: clinical symptoms, signs, imaging features and pathological results. Results all the 3 cases of fungal optic neuritis were middle-aged men with monocular or binocular diseases. Complicated with systemic diseases. The clinical manifestations were acute severe visual acuity, headache, eye distension, eyelid droop and ocular movement disorder. Ct showed soft tissue density shadow and bone resorption in the lateral wall of orbit. Abnormal (MRI) signal in orbit with irregular enhancement and unclear boundary. Hyphal spore and mycelium were found in histopathology. The symptoms were improved and stable after long-term anti-fungal therapy. Conclusion the acute unilateral visual acuity with headache and distended eyeball pain should be taken into account the possibility of fungal infection. Imaging examination was used to assist the diagnosis, and pathological biopsy was the diagnostic gold standard. Surgical removal of lesions and long-term anti-fungal therapy should be performed in time.
【作者單位】： 解放軍總醫(yī)院眼科;
【基金】：國家高科技研究發(fā)展計(jì)劃(863計(jì)劃)基金(2015AA020511)
【分類號(hào)】：R774.61

【相似文獻(xiàn)】

相關(guān)期刊論文 前2條

1 hanzy S. ,Routon M.C. ,Bursztyn J. ,陳立軍;1例12歲患兒因上頜竇炎、蝶竇炎引發(fā)急性感染性視神經(jīng)炎[J];世界核心醫(yī)學(xué)期刊文摘.眼科學(xué)分冊(cè);2005年06期

2 ;[J];;年期

，

本文編號(hào)：2189200