糖尿病性黃斑水腫視網(wǎng)膜功能定量研究
發(fā)布時(shí)間:2018-06-26 23:09
本文選題:糖尿病性黃斑水腫 + 多焦視網(wǎng)膜電圖。 參考:《國際眼科雜志》2016年09期
【摘要】:目的:應(yīng)用多焦視網(wǎng)膜電圖評(píng)估糖尿病性黃斑水腫的視網(wǎng)膜功能。方法:選取2010-03/2014-03我院眼科經(jīng)眼底血管造影檢查確診為糖尿病性黃斑水腫的患者30例48眼為觀察組(其中局限性水腫18眼,彌漫性水腫24眼,囊樣水腫6眼),選取視力0.8以上,經(jīng)裂隙燈顯微鏡檢查均未發(fā)現(xiàn)異常,全身情況無異常者15例30眼為對(duì)照組,兩組研究對(duì)象均行多焦視網(wǎng)膜電圖檢查,并對(duì)其結(jié)果進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果:糖尿病性黃斑水腫組多焦視網(wǎng)膜電圖中心凹、黃斑區(qū)、黃斑外區(qū)a、b波的振幅密度與對(duì)照組相比均差異存在統(tǒng)計(jì)學(xué)意義(P0.01);中心凹處觀察組和對(duì)照組a波的振幅密度分別為25.2±10.48、37.93±7.19nv/deg2,b波的振幅密度分別為77.16±27.97、113.42±11.79nv/deg2;黃斑區(qū)觀察組和對(duì)照組a波的振幅密度分別為14.27±4.99、27.42±2.86nv/deg2,b波的振幅密度分別為43.14±14.77、69.99±10.07 nv/deg2;黃斑外區(qū)觀察組和對(duì)照組a波的振幅密度分別為7.82±2.79、11.46±1.54nv/deg2,b波的振幅密度分別為19.85±6.5、31.56±6.0nv/deg2。中心凹處、黃斑區(qū)及黃斑外區(qū)多焦視網(wǎng)膜電圖a、b波振幅密度在局限性黃斑水腫組與彌漫性黃斑水腫組和囊樣黃斑水腫組間均存在統(tǒng)計(jì)學(xué)意義(P0.01)。結(jié)論:糖尿病性黃斑水腫的多焦視網(wǎng)膜表現(xiàn)為a、b波振幅密度下降,潛伏期延長(zhǎng),振幅密度比潛伏期敏感。
[Abstract]:Objective: to evaluate the retinal function of diabetic macular edema by multi-focal electroretinogram. Methods: thirty patients (48 eyes) with diabetic macular edema (18 eyes of local edema, 24 eyes of diffuse edema, 6 eyes of cystic edema) were selected as the observation group. The visual acuity was more than 0.8 in 30 patients with diabetic macular edema confirmed by fundus angiography in 2010-03 / 2014-03 ophthalmology, including 18 eyes of localized edema, 24 eyes of diffuse edema and 6 eyes of cystic edema. No abnormality was found by slit lamp microscope, and 15 cases (30 eyes) with no abnormal systemic condition were taken as the control group. The two groups were examined by multifocal electroretinogram, and the results were analyzed statistically. Results: in diabetic macular edema group, the central fovea, macular area, and multifocal electroretinogram were observed. The amplitude density of a b wave in the extramacular area was significantly different from that in the control group (P0.01), the amplitude density of a wave in the fovea observation group and the control group was 25.2 鹵10.4837.93 鹵7.19nv / deg2b wave, respectively, 77.16 鹵27.97113.42 鹵11.79nv / deg2nvdeg2 in the macular area observation group and control group, and in the macular area observation group and the control group, the amplitude density was 77.16 鹵27.97113.42 鹵11.79nv / deg2, respectively. The amplitude densities of a wave were 14.27 鹵4.99 鹵27.42 鹵2.86 nvdeg2b and 7.82 鹵2.79 11.46 鹵1.54 nvdeg2b, 19.85 鹵6.5nvdeg2b and 19.85 鹵6.5 鹵6.56 鹵6.0nvr / deg2, respectively, and the amplitude densities of a wave were 7.82 鹵2.7911.46 鹵1.54nvdeg2b, respectively, and the amplitude densities of a wave were 19.85 鹵6.5nv-31.56 鹵6.0nvrdeg2nvdeg2.The amplitude densities of a wave were 7.82 鹵2.7911.46 鹵1.54nvdeg2b and 19.85 鹵6.5nv-31.56 鹵6.0nvrdeg2 respectively. There was a significant difference in the amplitude density of afib wave between localized macular edema group, diffuse macular edema group and cystic macular edema group (P0.01). Conclusion: the multifocal retinal manifestations of diabetic macular edema are the decrease of amplitude density, the prolongation of latency and the sensitivity of amplitude density to latency.
【作者單位】: 中國河北省石家莊市第一醫(yī)院眼科;
【分類號(hào)】:R587.2;R774
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