本文選題：阻塞性睡眠呼吸暫停綜合征 + 冠狀動(dòng)脈��； 參考：《山東醫(yī)藥》2017年33期

【摘要】：目的探討不同海拔地區(qū)藏、漢族阻塞性睡眠呼吸暫停綜合征(OSAS)患者冠狀動(dòng)脈及頸動(dòng)脈病變程度的差異。方法選取西寧地區(qū)(平均海拔2 260m)和玉樹地區(qū)(平均海拔3 000 m)OSAS患者78例,依據(jù)海拔、民族不同分為西寧漢族組21例、西寧藏族組19例、玉樹漢族組18例、玉樹藏族組20例。對(duì)四組行24 h動(dòng)態(tài)血壓監(jiān)測,檢測平均收縮壓、平均舒張壓、24 h收縮壓變異系數(shù)、日間收縮壓變異系數(shù)、夜間收縮壓變異系數(shù)、24 h舒張壓變異系數(shù)、日間舒張壓變異系數(shù)、夜間舒張壓變異系數(shù);行冠狀動(dòng)脈CT檢查,采用Gensini加權(quán)積分評(píng)價(jià)冠狀動(dòng)脈狹窄程度;行頸動(dòng)脈血管彩超檢查,采用Crouse加權(quán)積分評(píng)價(jià)頸動(dòng)脈病變程度。結(jié)果玉樹藏、漢族組24 h舒張壓變異系數(shù)分別高于西寧同民族組,差異有統(tǒng)計(jì)學(xué)意義(P均0.05);西寧藏、漢族組冠狀動(dòng)脈狹窄程度Gensini積分及頸動(dòng)脈病變Crouse積分高于玉樹同民族組,差異有統(tǒng)計(jì)學(xué)意義(P均0.05);同海拔地區(qū)不同民族組冠狀動(dòng)脈狹窄程度Gensini積分及頸動(dòng)脈病變Crouse積分無差異(P均0.05)。結(jié)論不同海拔地區(qū)藏、漢族OSAS患者冠狀動(dòng)脈及頸動(dòng)脈病變程度存在差異,同海拔環(huán)境下藏、漢族OSAS患者冠狀動(dòng)脈及頸動(dòng)脈病變程度無差別。
[Abstract]:Objective to investigate the degree of coronary artery and carotid artery lesions in patients with obstructive sleep apnea syndrome (OSAS) in different altitude. Methods Seventy-eight patients with OSAS in Xining area (mean altitude 2260 m) and Yushu area (mean altitude 3 000 m) were divided into Xining Han nationality group (21 cases), Xining Tibetan group (19 cases), Yushu Han nationality group (18 cases) and Yushu Tibetan group (20 cases). 24 h ambulatory blood pressure monitoring was performed in the four groups. The mean systolic blood pressure, the mean diastolic blood pressure at 24 h, the daytime systolic blood pressure variation coefficient, the night systolic blood pressure variation coefficient at 24 h, the daytime diastolic blood pressure variation coefficient at 24 h, and the daytime diastolic blood pressure variation coefficient were measured. The variation coefficient of nighttime diastolic blood pressure was evaluated by coronary CT, and the degree of coronary artery stenosis was evaluated by Gensini weighted score, carotid artery color Doppler ultrasonography and Crouse weighted score. Results the coefficient of variation of diastolic blood pressure in Yushu Tibet group and Han nationality group was higher than that in Xining nationality group (P < 0.05), the Gensini score of coronary artery stenosis and the carotid artery lesion Crouse score in Xining Tibetan and Han nationality group were higher than those in Yushu nationality group. There was no significant difference in Gensini score and Crouse score of coronary artery stenosis in different ethnic groups at the same altitude, and there was no significant difference in Gensini score and Crouse score for carotid artery lesions in different ethnic groups at the same altitude. Conclusion the degree of coronary artery and carotid artery lesions in patients with OSAS in Han nationality is different from that in different altitude areas, but there is no difference in the degree of coronary artery and carotid artery lesions in patients with OSAS in Han nationality at the same altitude.
【作者單位】： 保定市第二中心醫(yī)院;青海省人民醫(yī)院;
【基金】：青海省科學(xué)技術(shù)廳(應(yīng)用)基礎(chǔ)研究計(jì)劃項(xiàng)目(2014-ZJ-741)
【分類號(hào)】：R766

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本文編號(hào)：2014210