發(fā)布時(shí)間：2018-06-10 15:16

  本文選題：經(jīng)皮電刺激 + 頦舌肌��； 參考：《南京醫(yī)科大學(xué)》2015年碩士論文

【摘要】：目的:評(píng)價(jià)無(wú)創(chuàng)經(jīng)皮頦舌肌電刺激對(duì)懸雍垂腭咽成形術(shù)后(Uvulopalatopharyngoplasty,UPPP)仍殘留輕中度阻塞性睡眠呼吸暫停綜合征(Obstructive sleep apnea syndrome,OSAS)患者的療效。方法:選擇23例UPPP術(shù)后經(jīng)多導(dǎo)睡眠監(jiān)測(cè)(PSG)顯示仍存留輕中度OSAS的患者,夜間給予經(jīng)皮頦舌肌電刺激治療。分別在治療前及治療時(shí)行多導(dǎo)睡眠監(jiān)測(cè)(Polysomnography,PSG),并依據(jù)Epworth睡眠量表(Epworth sleepiness scale,ESS)給OSAS患者進(jìn)行嗜睡評(píng)分;然后比較治療前及治療中的PSG參數(shù)及治療對(duì)白日嗜睡評(píng)分有無(wú)統(tǒng)計(jì)學(xué)差異。結(jié)果:與治療前相比,OSAS患者治療中的夜間呼吸暫停低通氣指數(shù)(Apnea hypopnea index,AHI)、微覺(jué)醒指數(shù)(Microarousal index,MAI)、睡眠期間SpO2低于90%時(shí)間占總睡眠時(shí)間的百分比(T90)及白日的ESS評(píng)分降低(9.2±4.2比17.9±6.9,P=0.000;6.3±3.8比10.9±4.9,P=0.000;4.9%±4.0%比9.1%±4.2%,P=0.000;8.7±3.4比9.3±3.1,P=0.002),并且平均SpO2和最低SpO2均顯著升高(95.5%±1.0%比94.4%±1.1%,P=0.000;88.7%±2.9%比85.2%±4.7%,P=0.000);患者治療中無(wú)明顯不適主訴。結(jié)論:經(jīng)皮頦舌肌電刺激治療可以改善OSAS患者睡眠呼吸紊亂及白日嗜睡狀況,其對(duì)UPPP術(shù)后仍存留輕中度OSAS的患者不失為一種安全、有效的治療方法。
[Abstract]:Objective: to evaluate the efficacy of noninvasive genioglossus electromyography in patients with mild to moderate obstructive sleep apnea syndrome (OSAs) after uvulopalatopharyngoplasty. Methods: Twenty-three patients with mild to moderate OSAS were treated with percutaneous genioglossus electromyography (PSG) after UPPP. Polysomnography PSG was performed before and after treatment, and the somnolence scores were evaluated according to Epworth sleepiness scale, and then the parameters of PSG before and during treatment were compared. Results: compared with before treatment, the nocturnal apnea hypopnea index (Apnea hypopnea index), microarousal index (microarousal index), the percentage of SPO 2 less than 90% of total sleep time (T90) and the daytime ESS score decreased by 9.2 鹵4.2 vs 17.9 鹵6.9P0. 000g / L and 6.3 鹵3.8 respectively. Compared with 10.9 鹵4.9% 鹵4.0% 鹵4.1% 鹵4.2%, 8.7 鹵3.4 vs 9.3 鹵3.1 P0. 002, the average SPO 2 and the lowest SPO 2 were significantly increased by 95.5% 鹵1.0% vs 94.4% 鹵1.1 P0.0007% 鹵2.9% vs 85.2% 鹵4.7% respectively. Conclusion: percutaneous genioglossal electromyography stimulation can improve sleep apnea disorder and daytime sleepiness in patients with OSAS. It is a safe and effective treatment for patients with mild to moderate OSAS after UPPP.
【學(xué)位授予單位】：南京醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R766.9

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