本文選題：阻塞性睡眠呼吸暫停低通氣綜合征 + 軟腭��； 參考：《吉林大學(xué)學(xué)報(bào)(醫(yī)學(xué)版)》2017年03期

【摘要】：目的:探索咽側(cè)壁分層縫合(SSLPW)聯(lián)合軟腭低溫等離子消融治療重度阻塞性睡眠呼吸暫停低通氣綜合征(OSAHS)患者的可行性和臨床效果。方法:收集行咽側(cè)壁成形術(shù)(LP)聯(lián)合軟腭低溫等離子消融術(shù)治療的21例重度OSAHS患者(LP組)和行SSLPW聯(lián)合軟腭低溫等離子消融術(shù)治療的39例重度OSAHS患者(SSLPW組)的臨床資料,回顧性分析2組患者術(shù)前和術(shù)后呼吸暫停低通氣指數(shù)(AHI)、最低動脈血氧飽和度(LSaO_2)、Epworth嗜睡量表(ESS)評分及術(shù)后相關(guān)并發(fā)癥發(fā)生情況,并比較2組患者的手術(shù)成功率。結(jié)果:LP組患者治愈1例(5%),顯效19例(90%),有效1例(5%),無效0例,手術(shù)成功率為95.2%(20/21);SSLPW組患者治愈2例(5.1%),顯效33例(84.6%),有效4例(10.3%),無效0例,手術(shù)成功率為89.7%(35/39);2組患者手術(shù)成功率比較差異無統(tǒng)計(jì)學(xué)意義(P0.05)。2組患者主觀癥狀均明顯改善,術(shù)后1個月隨訪未出現(xiàn)鼻咽部反流及吞咽困難。與術(shù)前比較,2組患者術(shù)后AHI和ESS評分降低(P0.05),LSaO_2升高(P0.05)。結(jié)論:SSLPW聯(lián)合軟腭低溫等離子消融術(shù)后患者AHI、LSaO_2及ESS評分均改善明顯,其可以作為治療重度OSAHS患者的良好手段。
[Abstract]:Objective: To explore the feasibility and clinical effect of lateral pharyngeal wall suture (SSLPW) combined with soft palate plasma ablation for severe obstructive sleep apnea hypopnea syndrome (OSAHS). Methods: 21 severe OSAHS patients (group LP) and SSLPW combined with lateral wall plasty (LP) combined with soft palate hypothermia plasma ablation were collected. The clinical data of 39 severe OSAHS patients (group SSLPW) treated with soft palate cryogenic plasma ablation were analyzed retrospectively in 2 groups of patients with apnea hypopnea index (AHI), minimum arterial oxygen saturation (LSaO_2), Epworth sleepiness scale (ESS) and postoperative complications, and the operation of 2 groups of patients was compared. Results: in group LP, 1 cases (5%) were cured, 19 cases (90%) were markedly effective, 1 cases were effective (5%), 0 cases were invalid, the operation success rate was 95.2% (20/21); the patients in group SSLPW were cured 2 (5.1%), significant 33 (84.6%), valid 4 cases (19), invalid cases, and the success rate of operation was 35/39 (P0.05) group.2 patients. The subjective symptoms were obviously improved, and no nasopharyngeal reflux and dysphagia were found at 1 months after operation. Compared with the preoperative, the scores of AHI and ESS in the 2 groups were decreased (P0.05) and LSaO_2 increased (P0.05). Conclusion: the AHI, LSaO_2 and ESS scores of patients with SSLPW combined with soft palate hypothermic plasma ablation were improved significantly, which could be used as a treatment for severe OSAHS. The good means of the person.
【作者單位】： 錦州醫(yī)科大學(xué)附屬火箭軍總醫(yī)院研究生培養(yǎng)基地;中國人民解放軍火箭軍總醫(yī)院耳鼻咽喉-頭頸外科;
【基金】：中國人民解放軍總后勤部衛(wèi)生局全軍“十二五”技術(shù)課題面上項(xiàng)目資助課題(CWS11J034);中國人民解放軍總后勤部衛(wèi)生局全軍保健專項(xiàng)資助課題(15BJZ23)
【分類號】：R766

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