本文選題：梅尼埃病 + 膜迷路積水　； 參考：《福建醫(yī)科大學(xué)》2012年碩士論文

【摘要】：目的：本研究旨在通過經(jīng)鼓室內(nèi)注射釓造影劑，24小時(shí)后行內(nèi)耳三維快速液體衰減反轉(zhuǎn)恢復(fù)核磁共振(three-dimensional fluid-attenuated inversionrecovery magnetic resonance imaging，3D-FLAIR MRI)掃描，與傳統(tǒng)經(jīng)典的膜迷路積水檢查方法，如前庭誘發(fā)肌源性電位(vestibular evoked myogenicpotential，VEMP)及耳蝸電圖（eleetrocochleography，EcochG）進(jìn)行比較，探討經(jīng)鼓室釓注射內(nèi)耳造影技術(shù)在梅尼埃病膜迷路積水中顯像的陽性率及對于梅尼埃病的診斷應(yīng)用價(jià)值。 方法：28例梅尼埃病患者，其中1例為雙側(cè)發(fā)病，共29患耳，經(jīng)鼓膜穿刺鼓室內(nèi)注入釓噴酸葡胺稀釋液，，24小時(shí)后進(jìn)行內(nèi)耳3D-FLAIR MRI掃描，并對檢查結(jié)果進(jìn)行總結(jié)、分析，同時(shí)與同期進(jìn)行的VEMP及耳蝸電圖檢查結(jié)果進(jìn)行比較。 結(jié)果：29耳成功造影28耳，成功率達(dá)96.6%。28耳造影成功患者內(nèi)耳磁共振成像顯示造影劑釓分布到內(nèi)耳外淋巴間隙，使外淋巴液顯影增強(qiáng)，從而區(qū)分出內(nèi)、外淋巴間隙。28耳中診斷膜迷路積水有26例，陽性率為92.9%（26/28），同期進(jìn)行的VEMP檢查陽性率為58.6%，耳蝸電圖檢查陽性率為60.7%，均小于釓注射內(nèi)耳造影技術(shù)，比較有統(tǒng)計(jì)學(xué)差異（P0.0125）。28例患者隨訪未見鼓膜穿孔、感染等并發(fā)癥。 結(jié)論：經(jīng)鼓室釓注射內(nèi)耳造影技術(shù)是檢測膜迷路積水的可靠的有效檢查手段。相比較傳統(tǒng)經(jīng)典檢查方法如VEMP、耳蝸電圖，陽性率更高，評估方法更科學(xué)，雖為有創(chuàng)性檢查但副作用較小，對于梅尼埃病具有重要的診斷價(jià)值和臨床意義。
[Abstract]:Objective: the aim of this study was to perform three-dimensional fluid-attenuated inversionrecovery magnetic resonance imaging3D-flair MRI scanning in the inner ear after 24 hours of intratympanic injection of gadolinium contrast agent. For example, vestibular evoked myogenic potentialpotential (VEMPP) and electrocochocardiography (EcochG) were compared to investigate the positive rate of intraventricular gadolinium injection in the diagnosis of Meniere's disease in membranous labyrinthine hydrops and its value in the diagnosis of Meniere's disease. Methods Twenty eight patients with Meniere's disease, including 1 patient with bilateral disease (29 ears), underwent 3D-FLAIR MRI scanning of the inner ear 24 hours after injection of Gadolinium Gadolinium poumate in the tympanic chamber through the tympanic membrane, and the results were summarized and analyzed. At the same time, the results of VEMP and electrocochocardiography were compared. Results Twenty eight ears were successfully examined, the success rate was 96.60.28 ears were successfully examined by magnetic resonance imaging (MRI) to show that the contrast agent gadolinium was distributed into the outer lymphoid space of the inner ear, which enhanced the development of perilymph and distinguished the inner part. In the perilymphatic space. 28 ears, 26 cases were diagnosed with membranous labyrinthine hydrops, the positive rate was 92.9 / 28, the positive rate of VEMP was 58.6, and the positive rate of electrocochocardiography was 60.7, which was less than that of gadolinium injection of inner ear. There were no complications such as tympanic membrane perforation, infection and so on. Conclusion: Intratympanic gadolinium injection is a reliable and effective method for the detection of membranous labyrinthine hydrops. Compared with traditional classical examination methods such as VEMPand electrocochocardiography, the positive rate is higher, the evaluation method is more scientific, although it is invasive examination, but the side effect is small, it has important diagnostic value and clinical significance for Meniere's disease.
【學(xué)位授予單位】：福建醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R764

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本文編號：1905843