本文選題：突發(fā)性耳聾 + 高壓氧��； 參考：《中國老年學(xué)雜志》2016年19期

【摘要】：目的探討高壓氧聯(lián)合鼓室灌注激素治療突發(fā)性耳聾的療效及對血液流變學(xué)的影響。方法突發(fā)性耳聾患者150例,按隨機數(shù)字表法分為激素組、高壓氧組和聯(lián)合組各50例。所有患者均常規(guī)給予擴血管、營養(yǎng)神經(jīng)及活血化瘀等藥物治療,在此治療基礎(chǔ)上,高壓氧組采用高壓氧治療,激素組患者經(jīng)鼓室灌注甲潑尼龍琥珀酸鈉40 mg,聯(lián)合組患者采用高壓氧及鼓室灌注甲潑尼龍琥珀酸鈉40 mg聯(lián)合治療。比較三組患者的聽閾水平、療效、血流變的改變情況及不良反應(yīng)發(fā)生情況。結(jié)果三組患者聽閾提高水平及治療有效率比較差異顯著(P0.05),依次為聯(lián)合組激素組高壓氧組。三組患者治療前的血液流變學(xué)指標無差異(P0.05),經(jīng)治療三組患者的血流變指標較治療前均明顯改善,且聯(lián)合組各項指標的改善情況均優(yōu)于激素組和高壓氧組(P0.05),激素組與高壓氧組比較無差異(P0.05)。三組不良反應(yīng)發(fā)生率比較無差異(P0.05)。結(jié)論高壓氧和鼓室灌注激素聯(lián)合治療能明顯改善突發(fā)性耳聾患者的血流變指標,恢復(fù)患者聽力,可在臨床借鑒使用。
[Abstract]:Objective to investigate the effect of hyperbaric oxygen combined with tympanic perfusion hormone on sudden deafness and its effect on hemorheology. Methods 150 patients with sudden deafness were randomly divided into hormone group, hyperbaric oxygen group and combined group. All the patients were treated with vasodilator, nutritional nerve, blood circulation and blood stasis. On the basis of this treatment, the hyperbaric oxygen group was treated with hyperbaric oxygen. The patients in the hormone group were treated with 40 mg methylprednisolone sodium succinate through the tympanic chamber, and the patients in the combined group were treated with hyperbaric oxygen and 40 mg sodium methylprednisolone succinate in the tympanic chamber. The hearing threshold level, curative effect, hemorrheological changes and adverse reactions were compared among the three groups. Results there were significant differences in the level of hearing threshold and the effective rate of treatment among the three groups (P 0.05), followed by hyperbaric oxygen group in the combined group. There was no difference in hemorheological indexes between the three groups before treatment. The hemorheological indexes of the three groups were significantly improved compared with those before treatment. The improvement of each index in the combined group was better than that in the hormone group and the hyperbaric oxygen group (P 0.05), but there was no difference between the hormone group and the hyperbaric oxygen group (P 0.05). There was no difference in the incidence of adverse reactions among the three groups (P 0.05). Conclusion the combination of hyperbaric oxygen and tympanic perfusion hormone can significantly improve the hemorheological index of sudden deafness patients and recover the hearing of the patients, which can be used for reference in clinical practice.
【作者單位】： 河北省人民醫(yī)院耳鼻喉科;
【分類號】：R764.437

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