OSAHS生物標記物的研究進展及意義
發(fā)布時間:2018-04-16 20:00
本文選題:睡眠呼吸暫停低通氣綜合征 + 阻塞性。 參考:《臨床耳鼻咽喉頭頸外科雜志》2017年19期
【摘要】:正近年來應用蛋白質組學、代謝組學技術探討OSAHS生物標記物的研究受到國內外學者的關注。本文就其研究進展進行綜述,以解決OSAHS在病因、診斷和治療方面的科學困境。1背景OSAHS可引起胸腔壓力波動、間歇性缺氧、微覺醒和睡眠片段化,隨后出現(xiàn)的交感神經(jīng)激活、氧化應激和炎性細胞因子與一系列的后遺癥,如高
[Abstract]:In recent years, the application of proteomics and metabonomics in the study of OSAHS biomarkers has attracted the attention of scholars at home and abroad.This paper reviews the research progress of OSAHS in order to solve the scientific dilemma in etiology, diagnosis and treatment. 1 background OSAHS can cause thoracic pressure fluctuation, intermittent hypoxia, microarousal, sleep fragmentation, and subsequent sympathetic activation.Oxidative stress and inflammatory cytokines are associated with a series of sequelae such as high
【作者單位】: 蚌埠醫(yī)學院附屬淮南市第一人民醫(yī)院耳鼻咽喉科;蚌埠醫(yī)學院附屬淮南市第一人民醫(yī)院神經(jīng)內科;蚌埠醫(yī)學院附屬淮南市第一人民醫(yī)院呼吸內科;
【分類號】:R766
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本文編號:1760372
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