本文選題：梅尼埃病　切入點：垂直半規(guī)管　出處：《遼寧醫(yī)學(xué)院》2012年碩士論文

【摘要】：目的 評估梅尼埃�。∕eniere disease,MD）患者垂直半規(guī)管功能的變化并分析梅尼埃病患者垂直半規(guī)管功能與水平半規(guī)管功能的相關(guān)性。 方法 應(yīng)用自主研發(fā)的SRM-IV全自動化良性陣發(fā)性位置性眩暈診斷治療系統(tǒng)，在被檢測者的垂直半規(guī)管處于垂直平面基礎(chǔ)上，采用180°非阻尼擺動試驗誘發(fā)垂直眼震，對45例正常人（對照組）及66例梅尼埃病的患者通過此方法進(jìn)行垂直半規(guī)管功能檢測，在誘發(fā)的同時記錄下相應(yīng)的眼震視頻和眼震曲線，并采集垂直眼震的方向及其慢相速度（slow phase velocity，SPV）參數(shù)。計算出右前半規(guī)管與左后半規(guī)管(right anterior semicircular canal and left posterior semicircularcanal, RALP)、左前半規(guī)管與右后半規(guī)管(left anterior semicircular canal and rightposterior semicircular canal, LARP)兩對垂直半規(guī)管垂直眼震平均慢相速度兩側(cè)不對稱比(canal paresis,CP)。同時，對MD患者行冷熱實驗，篩選出水平半規(guī)管功能異常的MD患者46例，并對該46例MD患者的垂直半規(guī)管功能進(jìn)行分析。 結(jié)果 66例梅尼埃病患者垂直眼震引出率為96.97%（128/132），兩對垂直半規(guī)管CP值范圍在0.13%-89.00%，其中2例雙側(cè)MD病患者未誘發(fā)出眼震，39例至少有一對垂直半規(guī)管之CP≥20%。不論是LARP垂直平面還是RALP垂直平面，MD患者誘發(fā)出的垂直眼震平均慢相速度（ASPV）均小于正常人，t檢驗有統(tǒng)計學(xué)差異。46例水平半規(guī)管功能異常的MD患者中，，垂直半規(guī)管功能異常者有33例，除2例雙側(cè)MD患者外，其余的31例均誘發(fā)出眼震；180°非阻尼擺動試驗檢測出的CP之減弱方向與冷熱試驗之CP方向一致者為63.64%。 結(jié)論 梅尼埃病患者不僅有水平半規(guī)管功能異常，同時也存在垂直半規(guī)管功能的異常。運用180°非阻尼擺動試驗可成功誘發(fā)垂直眼震，聯(lián)合冷熱試驗，有助于全面了解梅尼埃病患者半規(guī)管功能。
[Abstract]:objective
Objective to evaluate the changes of vertical semicircular canal function in patients with Meniere disease (MD) and analyze the correlation between vertical semicircular canal function and horizontal semicircular canal function in patients with Meynier disease (disease).
Method
The application of independent research and development SRM-IV automation of benign paroxysmal positional vertigo diagnosis and treatment system, the vertical semicircular canal were in a vertical plane on the basis of the 180 degree non induced damping swing test vertical nystagmus, 45 cases of normal people (control group) and 66 cases of Meniere's disease patients by the method of vertical semicircular canal function detection at the same time, in the corresponding record evoked nystagmus and video nystagmus and acquisition curve, vertical nystagmus direction and slow phase velocity (slow phase, velocity, SPV). The calculated parameters of right and left anterior semicircular canal (right anterior semicircular canal and left posterior semicircularcanal, RALP), the left and right anterior posterior semicircular canal (left anterior semicircular canal and rightposterior semicircular canal, LARP) two of the vertical semicircular canal vertical nystagmus slow phase velocity average asymmetry Compared with (canal paresis, CP). At the same time, cold and hot tests for MD patients were performed. 46 cases of MD with abnormal level of semicircular canal function were screened out, and the function of vertical semicircular canal in 46 patients with MD was analyzed.
Result
66 cases of Meniere's disease patients with vertical nystagmus (128/132) extraction rate was 96.97%, two of the vertical semicircular canal CP value in the range of 0.13%-89.00%, of which 2 cases of patients with bilateral MD disease did not induce nystagmus, 39 cases at least one of the CP vertical semicircular canal is greater than or equal to 20%. whether LARP or RALP plane perpendicular to the vertical plane, the induced MD patients the average vertical nystagmus slow phase velocity (ASPV) were less than normal, t significant.46 patients with horizontal semicircular canal function abnormalities in patients with MD, the vertical semicircular canal function abnormal in 33 cases, except 2 cases of bilateral MD patients, the remaining 31 cases were induced by nystagmus; non CP direction CP weakened direction detection a damping swing test and caloric test of 180 degrees the same as 63.64%.
conclusion
Patients with Meniere's disease is not only the horizontal semicircular canal function abnormal, but also the existence of abnormal vertical semicircular canal function. By 180 degrees non damping swing test can be successfully induced by vertical nystagmus, combined with cold and hot test, is conducive to a comprehensive understanding of the canal in patients with Meniere's disease.

【學(xué)位授予單位】：遼寧醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R764

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