本文選題：白內(nèi)障　切入點(diǎn)：人工晶狀體　出處：《川北醫(yī)學(xué)院》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:通過OQAS測(cè)量白內(nèi)障超聲乳化吸出聯(lián)合人工晶狀體(intraocular lens,IOL)植入術(shù)后患者的客觀散射指數(shù)(objective scatter index,OSI)、調(diào)制傳遞函數(shù)截止頻率(MTF cut off)、斯特列爾比(Strehl ratio,SR)、模擬對(duì)比度視力(OV100%,OV20%,OV9%),同時(shí)檢查波前像差和對(duì)比敏感度(contrast sensitivity,CS),評(píng)價(jià)球面和不同球差值非球面IOL的視覺質(zhì)量差異,探討非球面IOL眼是否比球面IOL眼有更好的視覺質(zhì)量、不同球差設(shè)計(jì)值的IOL視覺質(zhì)量差異。方法:前瞻、非隨機(jī)對(duì)照研究,227例349眼年齡相關(guān)性白內(nèi)障患者行白內(nèi)障超聲乳化吸出聯(lián)合IOL植入術(shù),其中植入BauschLomb球面IOL Akreos 69眼、AMO球面IOL AR40 67眼、BauschLomb非球面IOL Akreos AO(球差值0μm)70眼、Alcon非球面IOL SN60WF(球差值-0.20μm)71眼、AMO非球面IOL Tecnis ZCB00(球差值-0.27μm)72眼。術(shù)后3個(gè)月采用西班牙Visiometrics公司雙通道客觀視覺質(zhì)量分析系統(tǒng)(OQASTMⅡ)、日本Topcon公司KR-1W像差儀、美國(guó)Vector-Vision公司CSV-1000對(duì)比敏感度儀進(jìn)行檢查。比較OSI、MTF cut off、Strehl ratio、三種不同對(duì)比度的模擬視力(OV100%,OV20%,OV9%),同時(shí)比較波前像差儀和對(duì)比敏感度數(shù)據(jù)。結(jié)果:術(shù)后3個(gè)月,5組間UCVA、BCVA比較均無顯著性差異(P0.05)。CS在低空間頻率(3cpd)時(shí),植入球面IOL和非球面IOL患者無顯著性差異(P0.05),在中高空間頻率(6cpd、12cpd、18cpd)時(shí)均有顯著性差異,非球面IOL組優(yōu)于球面IOL組(P0.05);12cpd時(shí)ZCB00組優(yōu)于AO組(P0.05),其余空間頻率下各非球面IOL組間CS均無顯著性差異(P0.05)。五組間4mm及6mm瞳孔直徑下角膜高階像差均無顯著性差異(P0.05);植入球面IOL和非球面IOL患者4mm瞳孔直徑下眼內(nèi)球差(spherical aberration,SA)、全眼SA和6mm瞳孔眼內(nèi)SA、全眼總高階像差(total high order aberration,t HOA)、全眼SA有顯著性差異(P0.05);球面IOL AK組與AR40組間各項(xiàng)高階像差均無顯著性差異(P0.05);5組間4mm瞳孔直徑下眼內(nèi)SA、全眼SA有顯著性差異(P0.05);6mm瞳孔直徑下眼內(nèi)和全眼t HOA、SA有顯著性差異(P0.05);其余高階像差比較無顯著性差異(P0.05)。OSI、MTF cut off、Strehl ratio、OV100%、OV20%、OV9%非球面IOL組均優(yōu)于球面IOL組(P0.05);球面IOL AK組、AR40組與非球面IOL AO組間6項(xiàng)OQAS參數(shù)均無顯著性差異(P0.05);SN60WF組與ZCB00組間6項(xiàng)OQAS參數(shù)均無顯著性差異(P0.05);OSI:ZCB00組優(yōu)于AK組、AR40組、AO組(P0.05);MTF cut off:SN60WF組、ZCB00組均優(yōu)于AK組、AR40組(P0.05);Strehl ratio:SN60WF組、ZCB00組優(yōu)于AK組(P0.05);OV100%:SN60WF組、ZCB00組均優(yōu)于AK組、AR40組(P0.05);OV20%:SN60WF組優(yōu)于AK組、AR40組、AO組,ZCB00組優(yōu)于AK組(P0.05);OV9%:SN60WF組、ZCB00組均優(yōu)于AK組、AR40組(P0.05)。結(jié)論:球面和不同球差值非球面IOL植入術(shù)后視覺質(zhì)量有顯著性差異,非球面IOL眼視覺質(zhì)量明顯優(yōu)于球面IOL眼;不同球差值非球面IOL的視覺質(zhì)量比較中,AMO非球面IOL ZCB00(球差值-0.27μm)和Alcon非球面IOL SN60WF(球差值-0.20μm)優(yōu)于BauschLomb非球面IOL Akreos AO(球差值0μm);AMO非球面IOL ZCB00與Alcon非球面IOL SN60WF兩者OQAS視覺質(zhì)量指標(biāo)和CS均無顯著性差異;雙通道客觀視覺質(zhì)量分析系統(tǒng)(OQASTMⅡ)有獨(dú)特的散射光和其他視覺質(zhì)量評(píng)估指標(biāo),能定量分析,可以更加全面、客觀的評(píng)價(jià)非球面IOL植入術(shù)后的視覺質(zhì)量。
[Abstract]:Objective: through OQAS measurement in phacoemulsification and intraocular lenses (intraocular, lens, IOL) objective scatter index patients after implantation (objective scatter index, OSI), the cut-off frequency of modulation transfer function (MTF cut off) and Strehl ratio (Strehl, ratio, SR), the simulation contrast visual acuity (OV100%, OV20%, OV9%), and to check the wavefront aberration and contrast sensitivity (contrast, sensitivity, CS), to evaluate the visual quality differences of different ball spherical and aspheric IOL difference, to explore whether IOL eye aspheric is better than spherical IOL eye visual quality, IOL visual quality of different values of the spherical aberration design. Methods: a prospective, non randomized control study, 227 eyes of 349 patients with age-related cataract underwent phacoemulsification with IOL implantation, the implantation of BauschLomb spherical IOL Akreos 69 eyes, AMO spherical IOL AR40 67 eyes, BauschLomb aspheric IOL Akreo s AO(鐞冨樊鍊，

本文編號(hào)：1647955