本文選題：喉腫瘤　切入點：咽腫瘤　出處：《中國全科醫(yī)學》2017年24期 　論文類型：期刊論文

【摘要】：目的探討喉部或下咽部惡性腫瘤患者發(fā)生阻塞性睡眠呼吸暫停綜合征(OSAS)的影響因素,為防止腫瘤進一步生長、降低手術風險及術后并發(fā)癥、提高患者的生活質量提供幫助。方法選取2016年2—9月于鄭州大學第一附屬醫(yī)院耳鼻咽喉頭頸外科就診的符合納入標準的喉部或下咽部惡性腫瘤患者50例,并收集患者的臨床資料。采用便攜式睡眠監(jiān)測儀監(jiān)測患者睡眠呼吸暫停低通氣指數(AHI)、最低血氧飽和度等數據;其中AHI≥5次/h即可診斷為OSAS。根據患者是否發(fā)生OSAS,將其分為OSAS組和非OSAS組,比較兩組性別、年齡、體質指數(BMI)、腫瘤部位、腫瘤分期。并采用多因素Logistic回歸分析分析喉部或下咽部惡性腫瘤患者發(fā)生OSAS的影響因素。結果50例患者中男性較多,占94%;平均年齡(63.9±9.9)歲;平均BMI(22.5±3.0)kg/m~2;腫瘤部位:聲門上型13例(26%),聲門型25例(50%),下咽12例(24%);腫瘤分期:T_1期20例(40%),T_2期15例(30%),T_3期6例(12%),T_4期9例(18%);平均AHI(15.8±11.9)次/h;平均最低血氧飽和度72.8%±10.8%。50例患者中AHI≥5次/h 43例,即OSAS組43例,非OSAS組7例。OSAS組患者年齡大于非OSAS組患者(P0.05)。多因素Logistic回歸分析結果顯示,年齡是喉部或下咽部惡性腫瘤患者發(fā)生OSAS的危險因素[OR=1.133,95%CI(1.023,1.255),P=0.016]。結論喉部或下咽部惡性腫瘤患者OSAS發(fā)生率較高,且年齡是其發(fā)生OSAS的危險因素,而BMI、腫瘤部位、腫瘤分期與OSAS的發(fā)生無明顯關系。
[Abstract]:Objective to investigate the influencing factors of obstructive sleep apnea syndrome (OSAS) in patients with malignant tumor of larynx or hypopharynx, in order to prevent tumor from growing further and reduce the risk of operation and postoperative complications. Methods from February to September 2016, 50 patients with malignant tumor of larynx or hypopharynx were enrolled in the department of otolaryngology and head and neck surgery of the first affiliated Hospital of Zhengzhou University. The clinical data of patients were collected, and the data of AHIH and minimum oxygen saturation were monitored by portable sleep monitor in patients with sleep apnea hypopnea. AHI 鈮，

本文編號：1645269