本文選題：阻塞性睡眠呼吸暫停低通氣綜合征　切入點：認知功能　出處：《寧夏醫(yī)科大學》2012年碩士論文　論文類型：學位論文

【摘要】：目的探討扁桃體和（或）腺樣體切除術后，對阻塞性睡眠呼吸暫停低通氣綜合征兒童認知功能的影響。 方法術前對65名OSAHS患兒采用多導睡眠監(jiān)測和認知功能檢查（包括中國修訂版韋氏兒童智力量表、中國修訂版韋氏幼兒智力量表、注意力測試），在術后6個月進行相關隨訪，并與健康同齡兒童正常值比較，，數據采用SPSS11.5統(tǒng)計軟件進行分析。 結果①在韋氏幼兒智力量表的大部分項目上，學齡前期OSAHS患兒術后結果高于術前組，和健康兒童相比，僅在知識、畫圖填充分測驗中，有統(tǒng)計學意義；在言語智商、操作智商、總智商較術前均有提高，而和正常組相比三者均沒有統(tǒng)計學意義。②學齡組患兒術后和術前比較，在韋氏兒童智力量表的大部分項目上有顯著差異性，在知識、填圖數據上，術后OSAHS兒童的結果較正常組低；在言語智商、操作智商、總智商較術前均有顯著提高，同正常組比較無統(tǒng)計學意義；注意力測試結果術后患兒高于術前，而與正常兒童比較無統(tǒng)計學差異性。 結論阻塞性睡眠呼吸暫停低通氣綜合征，造成兒童認知功能損害，在手術治療后大部分認知功能可以恢復近正常，提示大部分受損的認知功能是可以逆轉的，因此需盡早進行手術干預。
[Abstract]:Objective to investigate the effects of tonsillectomy and / or adenoidectomy on cognitive function in children with obstructive sleep apnea hypopnea syndrome (OSAS). Methods Sixty-five children with OSAHS were examined with polysomnography and cognitive function (including China revised Wechsler Intelligence scale, Chinese revised Wechsler Intelligence scale and attention test), and were followed up 6 months after operation. Compared with the normal values of healthy children of the same age, the data were analyzed by SPSS11.5 software. Results (1) in most items of Wechsler Infant Intelligence scale, the postoperative results of pre-school children with OSAHS were higher than those of the preoperative group. Compared with the healthy children, there was statistical significance only in the knowledge and drawing filling subtest, and in the verbal intelligence quotient. Compared with the normal group, the three groups had no statistical significance. 2. There were significant differences in most items of Wechsler Children's Intelligence scale, and there were significant differences in the knowledge among the three groups, and there was no significant difference between the three groups before and after operation. In the mapping data, the results of postoperative OSAHS children were lower than those of the normal group, the verbal intelligence quotient, the operational intelligence quotient and the total intelligence quotient were significantly higher than those before the operation, but there was no statistical significance compared with the normal group, and the attention test results were higher than those before the operation. There was no statistical difference between children and normal children. Conclusion obstructive sleep apnea hypopnea syndrome can cause cognitive impairment in children. Most of the cognitive function can be restored to normal after operation, suggesting that most of the impaired cognitive function can be reversed. Therefore, surgical intervention should be carried out as soon as possible.
【學位授予單位】：寧夏醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R766

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