本文選題：LASIK　切入點：OCT　出處：《中南大學》2012年碩士論文　論文類型：學位論文

【摘要】：目的：通過對LASIK術患者角膜全層及角膜瓣厚度的測量,探討OCT在早期評估LASIK手術角膜瓣安全性中的應用。 方法：選擇湘雅三醫(yī)院門診行LASIK手術的患者38例(76眼),按等效球面屈光度分成中低度近視組(SE為-2.25～-6.00D)與高度近視組(SE為-6.00D～-9.50D)。分別測量其術前中央角膜厚度,術后第1天與第7天的角膜瓣厚度,術前、術后第1天與術后第7天的中央角膜上皮厚度,并觀察術后視力的變化。分析OCT在術前角膜測量值與A超測量值之間的差異；Moria90型角膜刀實測值與預設值的差別 結果：術前中央角膜厚度的OCT測量值小于A超測量值,兩者具有很好的相關性,不同屈光度組差異無統(tǒng)計學意義;90角膜刀術后第1天的中央角膜瓣厚度OCT實測平均值為136.96±12.06μm,高于預設值,術后第7天的平均中央角膜瓣厚度為132.71±13.17μm,也高于預設值,并且兩者角膜瓣厚度比較有統(tǒng)計學意義。中低度近視組與高度近視組之間差異無統(tǒng)計學意義；術前(50.83±3.71μm)、術后第1天(55.52±6.32μm)、術后第7天(53.435±4.62μm)的中央角膜上皮厚度有差異,術后第1天最高,術后第7天有所下降,但仍高于術前,中低度近視組與高度近視組差異無統(tǒng)計學意義, 結論：1.OCT可作為LASIK術前中央角膜厚度測量,以及術后早期中央角膜瓣厚度測量以及角膜上皮測量的一種方法。 2.術前中央角膜厚度的OCT測量值比A超測量值小,差異具有統(tǒng)計學意義。 3. Moria90刀的實測值高于預設值,術中應準確估計角膜刀的切削深度,預留更多的剩余角膜基質層厚度。
[Abstract]:Objective: to investigate the application of OCT in the early evaluation of corneal flap safety in LASIK patients by measuring the thickness of the whole cornea and corneal flap in patients undergoing LASIK. Methods: Thirty-eight patients (76 eyes) who underwent LASIK operation in Xiangya third Hospital were divided into middle and low myopia group (SE = -2.25) and high myopia group (SE = -6.00 DX -9.50 DX) according to equivalent spherical diopter. The preoperative central corneal thickness was measured. The thickness of corneal flap on the 1st and 7th day after operation, the central corneal epithelium thickness before operation, on the first day after operation and on the seventh day after operation, To analyze the difference between preoperative corneal measurement value and A-ultrasound value of OCT and the difference between Moria90 corneal knife test and preset value, and to observe the change of visual acuity after operation. Results: the OCT value of central corneal thickness before operation was less than that of A ultrasound, and there was a good correlation between them. There was no significant difference in the thickness of central corneal flap between different diopter groups (136.96 鹵12.06 渭 m) on the first day after operation. The mean thickness of central corneal flap on the 7th day after operation was 132.71 鹵13.17 渭 m, which was also higher than the preset value. There was no significant difference in corneal flap thickness between the middle and low myopia group and the high myopia group, the central corneal epithelium thickness was 50.83 鹵3.71 渭 m before operation, 55.52 鹵6.32 渭 m on the first day after operation, 53.435 鹵4.62 渭 m on the 7th day after operation, and the highest was on the first day after operation. On the 7th day after operation, there was a decrease, but it was still higher than that before operation. There was no significant difference between moderate and low myopia group and high myopia group. Conclusion 1. Oct can be used as a method to measure the central corneal thickness before LASIK, as well as the central corneal flap thickness and corneal epithelium in the early postoperative period. 2. The OCT value of central corneal thickness before operation was smaller than that of A ultrasound, and the difference was statistically significant. 3. The measured value of Moria90 knife is higher than that of preset, so the depth of keratectomy should be estimated accurately, and more residual corneal stromal thickness should be reserved.
【學位授予單位】：中南大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R779.63

【參考文獻】

相關期刊論文 前10條

1 沈政偉,王柏川,尹禾,黃震f^;薄角膜瓣對LASIK療效的影響[J];國際眼科雜志;2004年02期

2 杜紅俊,徐淵,王英,王雨生;LASIK術后繼發(fā)性圓錐角膜的預防和處理[J];國際眼科雜志;2005年02期

3 雷鳴,謝伯林,宮樞政,金淑芬,李琦云;準分子激光原位角膜磨鑲術813例的并發(fā)癥分析[J];國際眼科雜志;2005年03期

4 吳凌;樊瑜波;鄧應平;陳曉明;孫曉萍;謝毅;鄒遠文;黃學進;;兔眼LASIK術后角膜厚度和壓力的關系[J];國際眼科雜志;2007年05期

5 李誼;李上;馮聯(lián)兵;朱豫;;LASIK術后角膜瓣移位的臨床研究[J];國際眼科雜志;2008年07期

6 王娟;李雪非;張俊珠;賈紅江;于翠娟;包蘭菊;;LASIK術后角膜基質床及全角膜厚度的變化及相關因素分析[J];國際眼科雜志;2009年10期

7 黃楊利;馮馳;孫麗麗;;OCT與超聲角膜測厚儀測量角膜厚度結果的對比分析[J];國際眼科雜志;2011年01期

8 閆媛媛;;LASIK術后屈光度數(shù)回退原因分析[J];國際眼科雜志;2011年07期

9 朱映芳;劉玉君;;兩種LASIK角膜刀在低中度近視術中的臨床應用[J];國際眼科雜志;2011年10期

10 高煦;李立;杜之渝;;準分子激光原位角膜磨鑲術矯正中度以上近視術后5年屈光回退分析[J];檢驗醫(yī)學與臨床;2008年15期

相關博士學位論文 前1條

1 買志彬;FEMTO LDV飛秒激光輔助LASIK術后角膜形態(tài)和視覺質量的研究[D];鄭州大學;2010年

，

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