本文關(guān)鍵詞： 視網(wǎng)膜靜脈阻塞 黃斑水腫 中藥 激光 臨床研究　出處：《南京中醫(yī)藥大學(xué)》2012年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：客觀評價中藥聯(lián)合激光治療視網(wǎng)膜靜脈阻塞黃斑水腫的臨床療效,為中藥聯(lián)合激光治療視網(wǎng)膜靜脈阻塞黃斑水腫的臨床研究提供依據(jù)。 方法：本研究為回顧性非隨機性臨床干預(yù)研究。經(jīng)眼底檢查、視網(wǎng)膜血管熒光造影(Fluorescein Fondus Angiography, FFA)、光學(xué)相干斷層掃描(Optical Coherence Tomography,OCT)確診為視網(wǎng)膜靜脈阻塞黃斑水腫的患者30例(30眼)行中藥聯(lián)合激光治療,作為治療組,根據(jù)患者的具體情況予以黃斑水腫方為基礎(chǔ)方隨證加減,并聯(lián)合激光進行治療。在最佳矯正視力(Best Correct Visual Acuity, BCVA)、黃斑中心凹視網(wǎng)膜厚度(Central Subfield Thickness, CST)、黃斑容積(Cube Volume, CV)、黃斑區(qū)視網(wǎng)膜平均厚度(Cube Average Thickness, CAT)、黃斑區(qū)視網(wǎng)膜最大厚度(Cube Maximum Thickness, CMT)等方面進行治療前后的比較,對所得數(shù)據(jù)進行統(tǒng)計學(xué)處理,驗證中藥聯(lián)合激光治療本病的療效,分析患者性別、年齡、病程與療效是否具有相關(guān)性,并對治療組進行視力、黃斑區(qū)中心凹視網(wǎng)膜厚度、黃斑區(qū)平均視網(wǎng)膜厚度、黃斑容積以及黃斑區(qū)視網(wǎng)膜最大厚度有效率的評價。 結(jié)果：1.最佳矯正視力分析：治療組治療前后比較p0.05,其差異有統(tǒng)計學(xué)意義,表明治療組治療后視力有所提高；2.OCT結(jié)果分析：①黃斑巾心凹視網(wǎng)膜厚度：治療組前后比較為p0.05,其差異有統(tǒng)計學(xué)意義,表明治療組治療后黃斑中心凹視網(wǎng)膜厚度有所降低；②黃斑容積：治療組前后比較為p0.05,其差異有統(tǒng)計學(xué)意義,表明治療組治療后黃斑容積有所降低；③黃斑區(qū)視網(wǎng)膜平均厚度：治療組前后比較為p0.05,其差異有統(tǒng)計學(xué)意義,表明治療組治療后黃斑區(qū)視網(wǎng)膜平均厚度有所降低；④黃斑區(qū)視網(wǎng)膜最大厚度：治療組前后比較為p0.05,其差異有統(tǒng)計學(xué)意義,表明治療組治療后黃斑區(qū)視網(wǎng)膜最大厚度有所降低；3.療效分析：兩組治療后療效比較p0.05,差異有統(tǒng)計學(xué)意義,表明治療組療效優(yōu)于對照組。 結(jié)論：巾藥聯(lián)合激光治療能夠有效的改善視網(wǎng)膜靜脈阻塞黃斑水腫患者視網(wǎng)膜黃斑水腫的吸收,減少眼底的滲出,同時可以促進眼底出血的吸收,恢復(fù)視網(wǎng)膜形態(tài),促進視功能的提高。
[Abstract]:Objective: to evaluate the clinical efficacy of Chinese medicine combined with laser in the treatment of macular edema due to retinal vein occlusion. Methods: this study was a retrospective non-random clinical intervention study. Thirty patients (30 eyes) with macular edema due to retinal vein occlusion diagnosed by fluorescein Fondus angiography (FFAA) and optical coherence tomography (Oct) were treated with traditional Chinese medicine combined with laser therapy as treatment group. According to the patient's specific situation, the macular edema prescription is added or subtracted with the syndrome. At best corrected visual acuity (BCVA), macular central foveal retinal thickness (Correct), central Subfield retinal thickness (Correct), macular volume volume (Volumec), CVS, macular mean retinal thickness (MFT), cube Average Thickness, CATT, macular area retinal maximum thickness (MFT), macular area retinal maximum thickness (MFT), macular area retinal maximum thickness (MFT), macular area retinal maximum thickness (MSRT), macular area retinal maximum thickness (MFT), macular area retinal maximum thickness (MFT), CMT and other aspects of the comparison before and after treatment, The data were statistically processed to verify the curative effect of Chinese medicine combined with laser treatment, to analyze the correlation between sex, age, course of disease and curative effect, and to carry on the visual acuity, retinal thickness of fovea in macular area, and to analyze the correlation between the patients' sex, age, course of disease and curative effect. Evaluation of mean retinal thickness, macular volume, and maximum retinal thickness of macular area. Results 1.An analysis of best corrected visual acuity (BCVA): the difference between the treatment group and the treatment group before and after treatment (p0.05) was statistically significant. The results of Oct analysis showed that the retinal thickness of macular tissue in the treatment group was p0.05, and the difference was statistically significant. The results showed that the retinal thickness of macular fovea in the treatment group was lower than that in the control group (p 0.05), and the difference was statistically significant. The results showed that the mean retinal thickness of macular area in the treatment group was significantly lower than that in the control group (p 0.05). The results showed that the mean retinal thickness of macular area in the treatment group was lower than that in the control group (p 0.05), and the difference was statistically significant. The results showed that the maximum retinal thickness of macular area in the treatment group was lower than that in the control group (P 0.05), which indicated that the therapeutic effect of the treatment group was better than that of the control group. Conclusion: the combination of towel and laser therapy can effectively improve the absorption of retinal macular edema in patients with retinal vein occlusion and macular edema, reduce the exudation of the fundus, promote the absorption of fundus hemorrhage and restore the retinal morphology. Promote the improvement of visual function.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R774.5

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