本文關(guān)鍵詞： 阻塞性睡眠呼吸暫停低通氣綜合征 懸雍垂腭咽成形術(shù) 睡眠療效 生活質(zhì)量 遠(yuǎn)期效果　出處：《中華全科醫(yī)學(xué)》2016年07期 　論文類型：期刊論文

【摘要】：目的探討懸雍垂腭咽成形術(shù)對阻塞性睡眠呼吸暫停低通氣綜合征(OSAHS)患者遠(yuǎn)期療效及生活質(zhì)量的影響,為改善OSAHS患者預(yù)后提供臨床依據(jù)。方法選擇南潯區(qū)人民醫(yī)院2010年1月—2013年1月就診的50例中、重度OSAHS患者作為研究對象,均行懸雍垂腭咽成形術(shù)治療,于術(shù)前及術(shù)后1、12、24個月時檢測患者呼吸暫停通氣指數(shù)(AHI)、總睡眠時間、最低血氧飽和度(SaO_2)、3+4期睡眠比例、快速動眼睡眠比例和魁北克睡眠問卷(QSQ)測評,于術(shù)前及術(shù)后24個月時行Epworth嗜睡量表(ESS)測評,并對2組患者的檢測結(jié)果進(jìn)行統(tǒng)計學(xué)處理。結(jié)果在50例患者中共47例完成調(diào)查(94.00%);術(shù)后24個月,ESS測評結(jié)果顯著優(yōu)于術(shù)前(Z=2.611,P0.05);術(shù)后1、12、24個月時,SaO_2、3+4期睡眠比例、快速動眼睡眠比例均高于術(shù)前,AHI均低于術(shù)前(P0.05);術(shù)后12、24個月時,SaO_2、3+4期睡眠比例、快速動眼睡眠比例均高于術(shù)后1個月,AHI均低于術(shù)后1個月(P0.05);術(shù)后1、12、24個月時,QSQ各維度評分及總分均高于術(shù)前(P0.05);術(shù)后12、24個月時,QSQ各維度評分及總分均高于術(shù)后1個月(P0.05);術(shù)后12、24個月時,QSQ各維度評分及總分比較差異無統(tǒng)計學(xué)意義(P0.05)。結(jié)論懸雍垂腭咽成形術(shù)能夠顯著改善中、重度OSAHS患者的遠(yuǎn)期睡眠療效及生活質(zhì)量,明顯減輕了患者嗜睡程度,值得臨床重視。
[Abstract]:Objective to investigate the effect of uvulopalatopharyngoplasty on the long-term efficacy and quality of life in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Methods in order to improve the prognosis of patients with OSAHS, 50 patients with severe OSAHS were selected from Nanxun people's Hospital from January 2010 to January 2013. All patients were treated with uvulopalatopharyngoplasty. Apnea index (AHI), total sleep time, minimum blood oxygen saturation (SAO), sleep rate of stage 34, rapid eye movement (REM) sleep ratio and Quebec sleep questionnaire (QSQs) were measured before and after operation of 12 and 24 months. Epworth somnolence scale (Epworth) was used before and 24 months after operation. Results in 50 patients, 47 patients completed the investigation, and 24 months after operation, the results of ESS test were significantly better than that of pre-operation, 112m, 24 months after operation, and 24 months after operation, the sleep ratio of SaO2S stage 3 to 4 was significantly higher than that of pre-operation. The ratio of rapid eye movement sleep was higher than that of preoperative AHI, and the sleep ratio of Sao at 12 and 24 months after operation was lower than that of preoperation (P 0.05), and that of Sao at 12 and 24 months after operation was higher than that of preoperative AHI. The ratio of rapid eye movement sleep was higher than that of 1 month after operation (P 0.05), the scores and total scores of QSQ at 112 and 24 months after operation were higher than those before operation (P 0.05), and the scores and total scores of QSQ at 12 and 24 months after operation were higher than those at 1 month after operation. There was no significant difference in the scores and total scores of QSQ between 12 and 24 months after operation. Conclusion Uvulopalatopharyngoplasty can improve significantly. The long-term sleep effect and quality of life of patients with severe OSAHS have significantly reduced the degree of somnolence and deserve clinical attention.
【作者單位】： 湖州市南潯區(qū)人民醫(yī)院五官科;浙江大學(xué)湖州醫(yī)院呼吸內(nèi)科;
【基金】：2014年浙江省衛(wèi)計委平臺骨干人才項(xiàng)目(2014-RCA-029)
【分類號】：R766.9

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