本文關(guān)鍵詞：單點(diǎn)多次和多點(diǎn)一次性完成視網(wǎng)膜激光光凝對(duì)非增生期糖尿病視網(wǎng)膜病變的臨床療效對(duì)比觀察　出處：《臨床和實(shí)驗(yàn)醫(yī)學(xué)雜志》2016年12期 　論文類型：期刊論文

  更多相關(guān)文章： 糖尿病視網(wǎng)膜病變 視網(wǎng)膜激光光凝 視野閾值敏感度 激光掃描模式

【摘要】：目的探討單點(diǎn)多次和多點(diǎn)一次性完成視網(wǎng)膜激光光凝對(duì)非增生期糖尿病視網(wǎng)膜病變的臨床療效。方法將2011年6月至2014年6月醫(yī)院收治的86例(102只眼)非增生期DR患者按照隨機(jī)數(shù)字表法分為研究組43例(53只眼)和對(duì)照組43例(49只眼),研究組采用多點(diǎn)掃描模式一次性完成視網(wǎng)膜激光光凝,對(duì)照組采用單點(diǎn)掃描模式分3~5次完成視網(wǎng)膜激光光凝;比較兩組患者激光能量、光斑數(shù)、激光能量密度,分別于治療前、治療后1、3、6個(gè)月檢測(cè)兩組患者視野閾值敏感度、全視野閃光視網(wǎng)膜電圖a、b波振幅及黃斑中心凹厚度。結(jié)果研究組激光能量顯著高于對(duì)照組,光斑數(shù)、激光能量密度顯著低于對(duì)照組,兩組間比較差異具有統(tǒng)計(jì)學(xué)意義(P0.05);研究組和對(duì)照組最佳矯正視(BCVA)顯著提高(P0.05),兩組間BCVA比較差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);兩組治療前后及組間黃斑中心凹厚度(CMT)比較差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。治療后兩組患者全視野閃光視網(wǎng)膜電圖(F-ERG)a、b波振幅、視野閾值敏感度先呈降低趨勢(shì),然后逐漸上升,其中治療1個(gè)月、3個(gè)月兩組患者F-ERG a、b波振幅、視野閾值敏感均顯著低于治療前組(P0.05);兩組間治療前后各時(shí)段F-ERG a、b波振幅、視野閾值敏感比較差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。兩組患者治療后6個(gè)月隨訪期間均未出現(xiàn)明顯灌注區(qū)及新生血管等嚴(yán)重不良反應(yīng)。結(jié)論單點(diǎn)多次和多點(diǎn)一次性完成視網(wǎng)膜激光光凝治療非增生期DR對(duì)患者視力改善情況相當(dāng),而多點(diǎn)一次完成視網(wǎng)膜激光光凝能夠顯著降低能量密度,最大程度降低因激光治療對(duì)視網(wǎng)膜造成的損傷。
[Abstract]:Objective to investigate the clinical effect of single point multiple and multipoint laser photocoagulation in the treatment of non-proliferative diabetic retinopathy. Methods 86 cases of non-proliferative diabetic retinopathy were treated in our hospital from June 2011 to June 2014. 102 eyes) Non-proliferative Dr patients were randomly divided into study group (43 cases, 53 eyes) and control group (43 cases, 49 eyes). In the study group, the retinal laser photocoagulation was performed in a single point scanning mode, while in the control group, the retinal laser photocoagulation was completed in 3 to 5 times. Laser energy, spot number and laser energy density were compared between the two groups. The visual field threshold sensitivity and full field flash electroretinogram a were measured before treatment, 1 month after treatment and 6 months after treatment. Results the laser energy in the study group was significantly higher than that in the control group, and the number of spot and laser energy density in the study group were significantly lower than those in the control group. The difference between the two groups was statistically significant (P 0.05). The optimal corrected visual acuity (BCVA) in the study group and the control group was significantly higher than that in the control group (P 0.05). There was no significant difference in BCVA between the two groups. There was no significant difference in macular foveal thickness and CMT between the two groups before and after treatment (P 0.05). The amplitude of B wave and the sensitivity of visual field threshold were decreased firstly and then increased gradually. The amplitude of F-ERG afib wave in two groups were treated for 1 month and 3 months. The sensitivity of visual field threshold was significantly lower than that of pre-treatment group (P 0.05). The amplitude of F-ERG afib wave before and after treatment between the two groups. There was no significant difference in visual field threshold sensitivity (P0.05). There were no significant adverse reactions such as perfusion area and neovascularization during the follow-up of 6 months after treatment in both groups. Conclusion the retinal laser photocoagulation for non-proliferative phase Dr was performed at one point and multiple points at one time. The improvement is comparable. Multipoint laser photocoagulation can significantly reduce the energy density and minimize the retinal damage caused by laser therapy.
【作者單位】： 首都醫(yī)科大學(xué)燕京醫(yī)學(xué)院附屬密云醫(yī)院眼科;
【分類號(hào)】：R587.2;R774.1
【正文快照】： 分3~5次完成視網(wǎng)膜激光光凝;比較兩組患者激光能量、光斑數(shù)、激光能量密度,分別于治療前、治療后1、3、6個(gè)月檢測(cè)兩組患者視野閾值敏感度、全視野閃光視網(wǎng)膜電圖a、b波振幅及黃斑中心凹厚度。結(jié)果研究組激光能量顯著高于對(duì)照組,光斑數(shù)、激光能量密度顯著低于對(duì)照組,兩組間比較

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