本文關(guān)鍵詞：三維掃描技術(shù)評(píng)估瑞藍(lán)、美瑞兩種透明質(zhì)酸填充鼻唇溝效果　出處：《東南大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 面部三維掃描技術(shù) 鼻唇溝皺褶矯正 透明質(zhì)酸 量化評(píng)估

【摘要】：目的：通過面部三維掃描技術(shù)對(duì)瑞藍(lán)、美瑞兩種透明質(zhì)酸矯正鼻唇溝皺褶效果進(jìn)行量化評(píng)估,以觀察、比較兩種透明質(zhì)酸的作用特點(diǎn)與效果差異。方法：本研究通過對(duì)隨機(jī)分成兩組,美瑞組兩組,各組15人,共30例(28例女性,2例男性)鼻唇溝評(píng)分在3分、4分的患者,分別使用瑞藍(lán)、美瑞透明質(zhì)酸進(jìn)行鼻唇溝的注射填充,用V-TOP三維掃描儀采集其術(shù)前及術(shù)后20分鐘、一周、一月、三月、六月的三維數(shù)據(jù),并將鼻唇溝注射前的三維數(shù)據(jù)作為參考基線,采用Geomagic Qualify 13.0軟件測(cè)量比較患者鼻唇溝注射前后的三維數(shù)據(jù),量化評(píng)估鼻唇溝注射后變化,總結(jié)規(guī)律,比較不同種透明質(zhì)酸的效果差異。結(jié)果：1.對(duì)透明質(zhì)酸注射術(shù)后進(jìn)行并發(fā)癥及不良反應(yīng)的統(tǒng)計(jì),30例受試者25名術(shù)后局部無明顯異常；3名患者稍有腫脹、疼痛,一周內(nèi)自行好轉(zhuǎn)；2例患者局部出現(xiàn)了瘀青,囑局部進(jìn)行熱敷后一周左右消退。所有受試者均未出現(xiàn)變態(tài)過敏反應(yīng)、遲發(fā)性過敏反應(yīng)等嚴(yán)重的過敏反應(yīng)。2、GAIS評(píng)分結(jié)果示：瑞藍(lán)透明質(zhì)酸,術(shù)后20分鐘、一周、一月、三月、六月隨訪的改善率(除去惡化、無效的受試者),分別為100%、93.3%、83.3%、90%、80%。美瑞組結(jié)果分別為100%、100%、93.3%、83.3%、76.7%。表明兩種透明質(zhì)酸均有良好、持久的填充效果。3、利用面部三維掃描技術(shù)計(jì)算出,瑞藍(lán)組透明質(zhì)酸顯效系數(shù)的平均數(shù)：術(shù)后20分鐘、一周、一月、三月、六月分別為：0.678、0.729、0.578、0.542、0.466。美瑞透明質(zhì)酸各時(shí)間點(diǎn)顯效系數(shù)均值分別為：0.486、0.619、0.695、0.519、0.470。統(tǒng)計(jì)分析后得出各組隨訪時(shí)間對(duì)于顯效系數(shù)有明顯影響,且各時(shí)間點(diǎn)顯效系數(shù)不全相同。4、瑞藍(lán)透明質(zhì)酸顯效系數(shù)峰值出現(xiàn)在注射后一周,美瑞透明質(zhì)酸顯效系數(shù)峰值出現(xiàn)在填充后一月。結(jié)論：1、瑞藍(lán)、美瑞兩種透明質(zhì)酸注射填充矯正鼻唇溝皺褶具有很好的效果,且安全可靠。兩種透明質(zhì)酸填充效果均隨時(shí)間變化,且兩種透明質(zhì)酸長(zhǎng)期填充效果無明顯差異。2、本研究利用面部三維掃描技術(shù),提供了一種面部測(cè)量評(píng)估的新方法,具有臨床針對(duì)性,簡(jiǎn)便高效。
[Abstract]:Objective: to evaluate quantitatively the effect of two kinds of hyaluronic acid in correction of nasolabial crease by facial 3D scanning. Methods: this study was divided into two groups randomly, the two groups, 15 people in each group, a total of 30 cases of 28 women. Patients with nasolabial sulcus score of 3 and 4 were injected and filled with Raylan and Meridian, respectively. The patients were collected 20 minutes before and 20 minutes after operation by V-TOP 3D scanner. A week, January, March, June 3D data, and the nasolabial groove before injection of 3D data as a reference baseline. Geomagic Qualify 13.0 software was used to measure and compare the three dimensional data before and after nasolabial sulcus injection, to quantitatively evaluate the changes of nasolabial sulcus injection and to summarize the rule. Results: 1. Statistics of complications and adverse reactions after hyaluronic acid injection were performed in 30 subjects. There was no obvious local abnormality in 25 subjects after hyaluronic acid injection. Three patients had slight swelling and pain, and recovered within a week. Two patients suffered from local bruise, and were told to apply hot compress for a week or so. All the subjects had no abnormal allergic reaction, delayed allergic reaction and other serious allergic reactions. 2. GAIS score showed that the improvement rate of hyaluronic acid 20 minutes, one week, January, March and June was 93.3% respectively. The results of the Meirui group were 100 and 93.3, respectively, indicating that both kinds of hyaluronic acid were good. Lasting filling effect. 3. The mean value of hyaluronic acid apparent coefficient in the Raylan group was calculated by 3D facial scanning technique: 20 minutes, one week, January, March, June, respectively. The average apparent effect coefficient of Meridian at different time points was 0: 0. 486 / 0. 619 / 0. 695 ~ 0. 519 respectively. 0.470. After statistical analysis, it was concluded that the follow-up time of each group had a significant effect on the apparent effect coefficient, and the apparent effect coefficient was not all the same at each time point. The peak value of the apparent effect coefficient of Ruilan hyaluronic acid appeared one week after injection. The peak value of hyaluronic acid effective coefficient appeared on January after filling. Conclusion injection filling with two kinds of hyaluronic acid to cure nasolabial crease is effective. The filling effect of two kinds of hyaluronic acid varies with time, and the long-term filling effect of two kinds of hyaluronic acid has no obvious difference. A new method for evaluation of facial measurement is provided, which has clinical pertinence and is simple and efficient.
【學(xué)位授予單位】：東南大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R622;R765.9

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本文編號(hào)：1371805