肩袖修復(fù)重建的系列基礎(chǔ)研究
發(fā)布時間：2021-02-23 01:36
目的肩袖損傷是肩部最常見的病變之一,常需要手術(shù)治療。近年來,雖然肩袖修補術(shù)有著長足進步,術(shù)后的再撕裂率和并發(fā)癥的發(fā)生率仍然相當(dāng)高[1,2],肩袖與骨的愈合能力較差是造成術(shù)后再撕裂率偏高的主要原因。肩袖損傷后,腱-骨止點的結(jié)構(gòu)破壞,修補后的肌腱與骨的愈合只能形成纖維疤痕組織,從而容易再次損傷[3,4]。本實驗為了探究腱-骨愈合與力學(xué)刺激、內(nèi)環(huán)境和生物材料的關(guān)系,設(shè)計了一系列針對肩袖損傷修補及重建的基礎(chǔ)性研究。將原位肩袖組織進行穿骨隧道固定,探究隧道內(nèi)植入式肩袖修復(fù)方式中肌腱在骨隧道中的腱-骨愈合情況;并且利用雙極電紡纖維膜在腱-骨愈合處誘導(dǎo)腱-骨愈合中膠原纖維增生和骨長入,了解雙極納米纖維膜在肌腱與骨的愈合中的作用;在巨大肩袖損傷的治療中,利用自體肌腱橋接巨大肩袖損傷中肌腱與骨的缺損,與補片橋接法做對比,評估自體肌腱橋接修復(fù)治療巨大肩袖損傷的臨床可行性,通過觀察移植肌腱在骨隧道中的重塑,綜合了解肩袖修補和重建中的腱-骨愈合情況,尋找促進愈合的手術(shù)方式及新型生物材料方法加強腱-骨愈合的微結(jié)構(gòu)再生。方法1.取新西蘭白兔建立肩袖損傷模型,在足印區(qū)建立...
【文章來源】：上海交通大學(xué)上海市 211工程院校 985工程院校 教育部直屬院校
【文章頁數(shù)】：111 頁
【學(xué)位級別】：博士
【部分圖文】：
圖1.雙極納米纖維膜應(yīng)用于肩袖損傷修補的示意圖
圖 2 Into-tunnel repair 手術(shù)過程。(a)完整的岡上肌止點。（b）縱行劈開岡上肌肌腱殘端術(shù)。（c）分離編織后的岡上肌肌腱。（d）分離后的肌腱拉入骨隧道中Fig. 2. Repair procedures of the torn supraspinatus tendon (SSP) to the greater tuberosity(GT) in an into-tunnel manner. (a) Intact tendon-bone complex (b) Rotator cuff tear model wascreated and SSP split in half. (c) The split ends were sutured and two parallel bone tunnels werecreated from the decorticated site to the lateral aspect of greater tuberosity. (d) Each suturedtendon is inserted into the bone tunnel on GT and the attached suture firmly tied to the lateralaspect of the humeral cortex.
圖 2 Into-tunnel repair 手術(shù)過程。(a)完整的岡上肌止點。（b）縱行劈開岡上肌端術(shù)。（c）分離編織后的岡上肌肌腱。（d）分離后的肌腱拉入骨隧道中Fig. 2. Repair procedures of the torn supraspinatus tendon (SSP) to the greater tube(GT) in an into-tunnel manner. (a) Intact tendon-bone complex (b) Rotator cuff tear modecreated and SSP split in half. (c) The split ends were sutured and two parallel bone tunnelcreated from the decorticated site to the lateral aspect of greater tuberosity. (d) Each suttendon is inserted into the bone tunnel on GT and the attached suture firmly tied to the laaspect of the humeral cortex.
本文編號：3046826
【文章來源】：上海交通大學(xué)上海市 211工程院校 985工程院校 教育部直屬院校
【文章頁數(shù)】：111 頁
【學(xué)位級別】：博士
【部分圖文】：
圖1.雙極納米纖維膜應(yīng)用于肩袖損傷修補的示意圖
圖 2 Into-tunnel repair 手術(shù)過程。(a)完整的岡上肌止點。（b）縱行劈開岡上肌肌腱殘端術(shù)。（c）分離編織后的岡上肌肌腱。（d）分離后的肌腱拉入骨隧道中Fig. 2. Repair procedures of the torn supraspinatus tendon (SSP) to the greater tuberosity(GT) in an into-tunnel manner. (a) Intact tendon-bone complex (b) Rotator cuff tear model wascreated and SSP split in half. (c) The split ends were sutured and two parallel bone tunnels werecreated from the decorticated site to the lateral aspect of greater tuberosity. (d) Each suturedtendon is inserted into the bone tunnel on GT and the attached suture firmly tied to the lateralaspect of the humeral cortex.
圖 2 Into-tunnel repair 手術(shù)過程。(a)完整的岡上肌止點。（b）縱行劈開岡上肌端術(shù)。（c）分離編織后的岡上肌肌腱。（d）分離后的肌腱拉入骨隧道中Fig. 2. Repair procedures of the torn supraspinatus tendon (SSP) to the greater tube(GT) in an into-tunnel manner. (a) Intact tendon-bone complex (b) Rotator cuff tear modecreated and SSP split in half. (c) The split ends were sutured and two parallel bone tunnelcreated from the decorticated site to the lateral aspect of greater tuberosity. (d) Each suttendon is inserted into the bone tunnel on GT and the attached suture firmly tied to the laaspect of the humeral cortex.
本文編號：3046826
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