【摘要】：目的探討膝骨關(guān)節(jié)炎(OA)患者骨密度(BMD)的相關(guān)因素。方法收集192例膝OA患者,對(duì)患者一般情況行問(wèn)卷調(diào)查,用體重秤和身高計(jì)進(jìn)行身高、體重的測(cè)量,并計(jì)算體重指數(shù)(BMI),用雙能X線(xiàn)骨密度儀測(cè)量全身、髖部、脊柱(L1~L4)部位BMD和軀干、大腿的脂肪重量、肌肉重量,T≤-2.5為骨質(zhì)疏松癥(OP)。應(yīng)用單因素和多因素線(xiàn)性回歸方法分析全身、髖部、脊柱BMD與年齡、性別、BMI、吸煙、懷孕、絕經(jīng)、肌肉含量、脂肪含量的關(guān)系。結(jié)果骨質(zhì)疏松組與非骨質(zhì)疏松組間性別、BMI、吸煙、是否懷孕、懷孕次數(shù)、軀干脂肪重量、大腿脂肪重量差異均無(wú)統(tǒng)計(jì)學(xué)意義。與非骨質(zhì)疏松組相比,骨質(zhì)疏松組對(duì)象年齡更大,絕經(jīng)時(shí)間更長(zhǎng),身高、體重更低,軀干和大腿肌肉重量更低,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。年齡、女性、絕經(jīng)時(shí)間與全身、髖部及脊柱BMD呈顯著負(fù)相關(guān)性,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。BMI與脊柱BMD呈顯著正相關(guān)性;懷孕、大腿肌肉重量與全身、髖部及脊柱BMD呈顯著正相關(guān)性,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論增齡、女性、絕經(jīng)可能是膝OA患者BMD降低的危險(xiǎn)因素,BMI、懷孕和肌肉含量對(duì)膝OA患者的BMD可能具有保護(hù)作用。
[Abstract]:Objective to investigate the related factors of bone mineral density (BMD) in patients with knee osteoarthritis (OA). Methods 192 patients with knee OA were investigated by questionnaire. Height and weight were measured by weight scale and altimeter. Body mass index (BMI),) was measured by dual energy X-ray absorptimeter. BMD, trunk, thigh, muscle weight and T 鈮，

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