應(yīng)用三維掃描技術(shù)測量評估透明質(zhì)酸矯正鼻唇溝皺褶的術(shù)后效果
發(fā)布時間：2019-05-30 11:45
【摘要】：目的：通過三維掃描技術(shù)對以透明質(zhì)酸填充矯正鼻唇溝皺褶的術(shù)后效果進行量化評估分析,建立一種全新的面部鼻唇溝測量評估方法,并對該測量方法的可行性、精確性進行驗證。方法：本研究通過對40例鼻唇溝評分在3分、4分的受試者,使用透明質(zhì)酸進行鼻唇溝的注射填充,對受試者術(shù)前術(shù)后的鼻唇溝嚴重程度和面部整體美容效果進行了評價。以VTOP三維掃描儀采集其術(shù)前及術(shù)后各時間點的三維數(shù)據(jù),并將鼻唇溝注射前的三維數(shù)據(jù)作為參考基線,采用Geomagic Qualify 13.0軟件測量比較患者鼻唇溝注射前后的三維數(shù)據(jù),動態(tài)評估鼻唇溝注射前后的有效體積、2D尺寸、三維偏差的效果差異。結(jié)果：1.所有受試者均未出現(xiàn)變態(tài)過敏反應(yīng)、遲發(fā)性過敏反應(yīng)等嚴重的過敏反應(yīng),局部出現(xiàn)的腫脹、疼痛,無特殊處理于一周內(nèi)自行好轉(zhuǎn)。2.鼻唇溝嚴重程度及面部整體美容效果評價結(jié)果顯示受試者和研究者在各時間點的評分均值趨勢基本一致,注射后四個月鼻唇溝皺褶的評分均較注射前下降,面部整體美容效果的改善程度約75%,但受試者評分均值低于研究者評分低。3.以三維掃描軟件測得的鼻唇溝有效體積各時間點的比較,術(shù)后一周鼻唇溝部位測量體積為0.50ml,一月測量體積為0.56ml,二月測量體積為0.49ml,三月測量體積為0.43ml,四月時測量體積為0.32ml；并對不同時間點的測量體積與實際注射量之間進行了回歸分析,統(tǒng)計學(xué)結(jié)果顯示術(shù)后一周測量值與淺層注射量存在高度線性相關(guān)(R方=0.56,p0.05),而其它時間點均不存在線性相關(guān)。4.2D尺寸分析發(fā)現(xiàn)術(shù)后一周鼻外側(cè)區(qū)改善高度為2.38mm,術(shù)后一月為2.06mm,術(shù)后二月為2.Olmm,術(shù)后三月為1.48mm,至四月時為0.85mm,占術(shù)后一周的比值為35.6%,隨時間延長改善高度逐漸下降。5.精確度驗證中術(shù)后一周的有效體積測量值與實際注射量無差異,P0.05,沒有統(tǒng)計學(xué)意義。其回歸線性分析結(jié)果顯示二者具有高度相關(guān)的線性關(guān)系,P0.05,有統(tǒng)計學(xué)意義。可重復(fù)性驗證獲得的雙側(cè)測量值的標準差分別為0.032、0.018,該測量方法可重復(fù)性好、精確度高。結(jié)論：1.經(jīng)過四個月的臨床研究驗證三維掃描技術(shù)可以用來長期測量評估鼻唇溝皺褶填充的術(shù)后效果。2.該測量方法經(jīng)過驗證具有高精確度、良好的可重復(fù)性,值得進一步推廣應(yīng)用。3.透明質(zhì)酸注射填充矯正鼻唇溝皺褶具有很好的效果,且安全可靠。
[Abstract]:Objective: to quantitatively evaluate and analyze the postoperative effect of hyaluronic acid filling in correction of nasolabial groove fold by three-dimensional scanning technique, and to establish a new method for measuring and evaluating facial nasolabial groove, and the feasibility of this method is also discussed. Verify the accuracy. Methods: 40 subjects with nasolabial sulcus score of 3 and 4 were filled with hyaluronic acid, and the severity of nasolabial sulcus before and after operation and the overall facial cosmetic effect were evaluated. The three-dimensional data before and after injection were collected by VTOP three-dimensional scanner, and the three-dimensional data before injection of nasolabial sulcus were used as reference baseline. the three-dimensional data before and after injection were measured and compared by Geomagic Qualify 13.0 software. The effective volume, 2D size and three dimensional deviation of nasolabial groove before and after injection were evaluated dynamically. Results: 1. All the subjects did not have allergic reactions, delayed allergic reactions and other serious allergic reactions, local swelling, pain, no special treatment within a week self-improvement. 2. The evaluation results of the severity of nasolabial sulcus and the overall facial cosmetic effect showed that the average score of the subjects and the researchers at each time point was basically the same, and the score of nasolabial sulcus wrinkle decreased four months after injection compared with that before injection. The improvement of the overall facial beauty effect was about 75%, but the average score of the subjects was lower than that of the researchers. 3. The effective volume of nasolabial groove measured by three-dimensional scanning software was compared at each time point. The measured volume of labial sulcus was 0.50ml one week, 0.56ml in one month, 0.49ml in February and 0.43ml in three months. The measured volume was 0.32 ml in April. The regression analysis was carried out between the measured volume and the actual injection volume at different time points. The statistical results showed that there was a high linear correlation between the measured volume and the shallow injection volume one week after operation (R square = 0.56, p0.05). There was no linear correlation at other time points. 4.2D size analysis showed that the height of the lateral nasal area was 2.38 mm, 2.06 mm, 2.Olmm 2 months, 1.48 mm 3 months and 0.85 mm 1 month, 2.06 mm, 1.48 mm and 0.85 mm respectively one week after operation, 2.06 mm 1 month, 2.Olmm 2 months after operation, 1.48 mm 3 months after operation and 0.85 mm at 4 months after operation. The ratio of 35.6% was 35.6% one week after operation, and the height decreased gradually with the prolongation of time. 5. There was no significant difference between the effective volume measurement and the actual injection volume one week after operation, but there was no significant difference between P0.05 and the actual injection volume. The results of regression linear analysis showed that there was a highly correlated linear relationship between them, P0.05, which was statistically significant. The standard deviation of bilateral measurements obtained by repeatability verification is 0.032 and 0.018, respectively. the method has good repeatability and high accuracy. Conclusion: 1. After four months of clinical study, it has been verified that three-dimensional scanning technique can be used to measure and evaluate the postoperative effect of nasal labial groove wrinkle filling for a long time. 2. The measurement method has been proved to have high accuracy and good repeatability, and it is worth further popularizing and applying. Hyaluronic acid injection filling has a good effect on correction of nasal labial groove wrinkle, and it is safe and reliable.
【學(xué)位授予單位】：東南大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R62;R765.9
本文編號：2488808
[Abstract]:Objective: to quantitatively evaluate and analyze the postoperative effect of hyaluronic acid filling in correction of nasolabial groove fold by three-dimensional scanning technique, and to establish a new method for measuring and evaluating facial nasolabial groove, and the feasibility of this method is also discussed. Verify the accuracy. Methods: 40 subjects with nasolabial sulcus score of 3 and 4 were filled with hyaluronic acid, and the severity of nasolabial sulcus before and after operation and the overall facial cosmetic effect were evaluated. The three-dimensional data before and after injection were collected by VTOP three-dimensional scanner, and the three-dimensional data before injection of nasolabial sulcus were used as reference baseline. the three-dimensional data before and after injection were measured and compared by Geomagic Qualify 13.0 software. The effective volume, 2D size and three dimensional deviation of nasolabial groove before and after injection were evaluated dynamically. Results: 1. All the subjects did not have allergic reactions, delayed allergic reactions and other serious allergic reactions, local swelling, pain, no special treatment within a week self-improvement. 2. The evaluation results of the severity of nasolabial sulcus and the overall facial cosmetic effect showed that the average score of the subjects and the researchers at each time point was basically the same, and the score of nasolabial sulcus wrinkle decreased four months after injection compared with that before injection. The improvement of the overall facial beauty effect was about 75%, but the average score of the subjects was lower than that of the researchers. 3. The effective volume of nasolabial groove measured by three-dimensional scanning software was compared at each time point. The measured volume of labial sulcus was 0.50ml one week, 0.56ml in one month, 0.49ml in February and 0.43ml in three months. The measured volume was 0.32 ml in April. The regression analysis was carried out between the measured volume and the actual injection volume at different time points. The statistical results showed that there was a high linear correlation between the measured volume and the shallow injection volume one week after operation (R square = 0.56, p0.05). There was no linear correlation at other time points. 4.2D size analysis showed that the height of the lateral nasal area was 2.38 mm, 2.06 mm, 2.Olmm 2 months, 1.48 mm 3 months and 0.85 mm 1 month, 2.06 mm, 1.48 mm and 0.85 mm respectively one week after operation, 2.06 mm 1 month, 2.Olmm 2 months after operation, 1.48 mm 3 months after operation and 0.85 mm at 4 months after operation. The ratio of 35.6% was 35.6% one week after operation, and the height decreased gradually with the prolongation of time. 5. There was no significant difference between the effective volume measurement and the actual injection volume one week after operation, but there was no significant difference between P0.05 and the actual injection volume. The results of regression linear analysis showed that there was a highly correlated linear relationship between them, P0.05, which was statistically significant. The standard deviation of bilateral measurements obtained by repeatability verification is 0.032 and 0.018, respectively. the method has good repeatability and high accuracy. Conclusion: 1. After four months of clinical study, it has been verified that three-dimensional scanning technique can be used to measure and evaluate the postoperative effect of nasal labial groove wrinkle filling for a long time. 2. The measurement method has been proved to have high accuracy and good repeatability, and it is worth further popularizing and applying. Hyaluronic acid injection filling has a good effect on correction of nasal labial groove wrinkle, and it is safe and reliable.
【學(xué)位授予單位】：東南大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R62;R765.9
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