【摘要】：目的探討癥狀性大腦中動(dòng)脈M1段高度狹窄的患者行血管內(nèi)介入治療的有效性、安全性,以及并發(fā)癥發(fā)生的原因。方法對(duì)經(jīng)TCD、顱腦CT血管成像(computed tomography angiography,CTA)或腦血管造影術(shù)(digital subtraction angiograyhy,DSA)證實(shí)為大腦中動(dòng)脈M1段高度狹窄(90%)的256例患者進(jìn)行血管內(nèi)介入治療,對(duì)臨床癥狀變化,手術(shù)成功率、狹窄病變改善情況、遠(yuǎn)期血管通暢率以及支架內(nèi)再狹窄率進(jìn)行評(píng)估。結(jié)果251例(251/256)癥狀性大腦中動(dòng)脈M1段高度狹窄患者成功的進(jìn)行血管內(nèi)介入治療,手術(shù)成功率為98.05%。其中15例患者出現(xiàn)與神經(jīng)功能、死亡相關(guān)的并發(fā)癥(5.86%)。血管狹窄率從手術(shù)前(92.26%±2.11%)下降至術(shù)后(15.40%±2.60%)。平均m RS和NIHSS評(píng)分較術(shù)前明顯降低。術(shù)后平均隨訪(21.70±0.80)個(gè)月,249例患者接受腦血管造影復(fù)查,平均狹窄率為(12.81%±2.20%)。23例患者發(fā)生支架內(nèi)再狹窄(ISR),再狹窄率為9.24%,其中5例出現(xiàn)缺血性卒中再發(fā),復(fù)發(fā)率為2.01%。結(jié)論血管內(nèi)介入治療癥狀性大腦中動(dòng)脈M1段高度狹窄具有安全、有效的優(yōu)點(diǎn),手術(shù)并發(fā)癥低,隨訪結(jié)果顯示血管通暢率好以及較好的預(yù)防前循環(huán)缺血事件的發(fā)生。
[Abstract]:Objective to investigate the efficacy and safety of endovascular intervention in patients with symptomatic middle cerebral artery M1 segment stenosis and the causes of complications. Methods 256 patients with high stenosis of M1 segment of middle cerebral artery (90%) confirmed by TCD, craniocerebral CT angiography (computed tomography angiography,CTA) or cerebral angiography (digital subtraction angiograyhy,DSA) were treated with intravascular intervention. The success rate of operation, the improvement of stenosis, the long-term patency rate and the rate of restenosis in stent were evaluated. Results 251 patients (251 鈮，

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