人工髖關(guān)節(jié)置換術(shù)和PFNA內(nèi)固定治療股骨粗隆間骨折的對(duì)比研究
發(fā)布時(shí)間:2019-05-29 17:27
【摘要】:背景股骨粗隆間骨折是臨床上常見的疾病,多發(fā)生在老年人群中,且隨著人口老齡化的日益加劇,老齡人口的日益增多,導(dǎo)致股骨粗隆間骨折發(fā)生率呈現(xiàn)上升趨勢(shì)及年輕化趨勢(shì)。由于老年患者年齡較大,再加上患者常伴有神經(jīng)障礙、平衡能力較差,導(dǎo)致老年人骨折發(fā)生率更高。數(shù)據(jù)報(bào)道顯示:股骨粗隆間骨折占髖部骨折的31.%-51%,患者多由摔傷引起。同時(shí),老年人對(duì)創(chuàng)傷的修復(fù)能力較差,骨量的丟失、合并骨質(zhì)疏松等,導(dǎo)致股骨粗隆間骨折死亡率在15%-20.0%,嚴(yán)重影響我國老年人健康。目前,臨床上對(duì)于股骨粗隆間骨折治療方法相對(duì)較多,包括:DHS內(nèi)固定、PFNA內(nèi)固定、人工髖關(guān)節(jié)置換術(shù)等,導(dǎo)致臨床患者選擇何種治療方法存在很大的爭議。本課題以高齡股骨粗隆間骨折患者作為研究對(duì)象,采用人工髖關(guān)節(jié)置換術(shù)和PFNA內(nèi)固定進(jìn)行治療并評(píng)估其療效,為臨床股骨粗隆間骨折的治療提供思路。目的探討人工髖關(guān)節(jié)置換術(shù)和PFNA內(nèi)固定在粗隆間骨折患者中的臨床治療效果。方法取2014年1月-2016年10月醫(yī)院收治股骨粗隆間骨折患者140例,回顧性的分組分為對(duì)照組(n=70)和觀察組(n=70)。對(duì)照組采用PFNA內(nèi)固定治療,觀察組采用人工髖關(guān)節(jié)置換術(shù)治療,采用酶聯(lián)免疫吸附測(cè)定2組治療前、后白細(xì)胞介素-6(IL-6)、白細(xì)胞介素-10(IL-10)及腫瘤壞死因子-a(TNF-a)水平;采用Harris量表對(duì)患者關(guān)節(jié)功能進(jìn)行評(píng)估,采用SF-36量表對(duì)2組治療前、后生活質(zhì)量進(jìn)行評(píng)價(jià),記錄2組手術(shù)相關(guān)指標(biāo),包括:手術(shù)時(shí)間、出血量、術(shù)后引流量及臥床時(shí)間等,采集的數(shù)據(jù)均采用SPSS18.0軟件進(jìn)行處理。結(jié)果觀察組臥床時(shí)間、手術(shù)時(shí)間,均短于對(duì)照組(P0.05);觀察組出血量、術(shù)后引流量兩個(gè)方面均多于對(duì)照組(P0.05);2組術(shù)前Harris評(píng)分比較差異無統(tǒng)計(jì)學(xué)意義(P0.05);觀察組術(shù)后14d、術(shù)后1個(gè)月及3個(gè)月Harris評(píng)分,高于對(duì)照組(P0.05);2組治療前SF-36量表評(píng)分比較差異無統(tǒng)計(jì)學(xué)意義(P0.05);觀察組治療后生理職能、生理功能、軀體疼痛、總體健康、活力、情感職能、社會(huì)功能以及心理健康評(píng)分,高于對(duì)照組(P0.05);2組治療前TNF-a、IL-6及IL-10水平比較差異無統(tǒng)計(jì)學(xué)意義(P0.05);觀察組治療后3個(gè)月TNF-a、IL-6及IL-10水平,低于對(duì)照組(P0.05);觀察組手術(shù)治療后出現(xiàn)并發(fā)癥發(fā)生率為2.86%,對(duì)照組出現(xiàn)并發(fā)癥的發(fā)生率為11.43%,2組并發(fā)癥發(fā)生率比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論該研究為高齡股骨粗隆間骨折患者提供一種新的治療方法,在掌握好適應(yīng)癥的前提下,特別是對(duì)高齡合并基礎(chǔ)疾病,不能長期臥床股骨粗隆間骨折患者,采用人工關(guān)節(jié)置換術(shù),可以明顯縮短患者的臥床時(shí)間,提高患者早期的關(guān)節(jié)功能和生活質(zhì)量,縮短愈合時(shí)間,能降低炎癥因子水平,但是治療時(shí)應(yīng)該根據(jù)每一位患者實(shí)際情況選擇合適的治療方法,并且術(shù)前加強(qiáng)患者評(píng)估,全面了解患者病情,使得患者的治療更具有針對(duì)性。
[Abstract]:Background Intertrochanteric fracture of femur is a common clinical disease, which mostly occurs in the elderly population, and with the increasing aging of the population, the elderly population is increasing day by day. The incidence of intertrochanter fracture of femur showed an upward trend and a younger trend. Because the elderly patients are older, and the patients are often accompanied by neurological disorders and poor balance ability, the incidence of fracture in the elderly is higher. The data report showed that the intertrochanter fracture of the femur accounted for 31% 鈮,
本文編號(hào):2488088
[Abstract]:Background Intertrochanteric fracture of femur is a common clinical disease, which mostly occurs in the elderly population, and with the increasing aging of the population, the elderly population is increasing day by day. The incidence of intertrochanter fracture of femur showed an upward trend and a younger trend. Because the elderly patients are older, and the patients are often accompanied by neurological disorders and poor balance ability, the incidence of fracture in the elderly is higher. The data report showed that the intertrochanter fracture of the femur accounted for 31% 鈮,
本文編號(hào):2488088
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