【摘要】：目的探討術(shù)中穿刺快速檢測鑒別淋巴結(jié)和甲狀旁腺的可行性。方法選擇2014年1-7月第四軍醫(yī)大學(xué)西京醫(yī)院收治的28例甲狀腺癌病人,均行甲狀腺癌根治術(shù)。行術(shù)中冰凍病理學(xué)檢查的同時進行術(shù)中穿刺快速檢測,比較兩種方法的敏感度、特異度等診斷效能指標。結(jié)果 28例病人術(shù)中共檢出40枚可疑結(jié)節(jié),包含29枚可疑甲狀旁腺、9枚可疑淋巴結(jié)、2枚可疑結(jié)節(jié)。甲狀旁腺的術(shù)中總檢出率為27.5%(11/40),淋巴結(jié)的總檢出率為37.5%(15/40)。冰凍病理學(xué)檢查與術(shù)后病理學(xué)檢查一致,故以其為金標準,術(shù)中穿刺快速檢測鑒定淋巴結(jié)的準確率為100%,鑒定甲狀旁腺的準確率為93.1%(1例假陽性),敏感度為100%,特異度為97.0%。結(jié)論術(shù)中穿刺快速檢測可準確鑒別術(shù)中可疑淋巴結(jié),有助于甲狀旁腺的保護及原位保留。
[Abstract]:Objective to explore the feasibility of rapid detection of lymph nodes and parathyroid glands by intraoperative puncture. Methods from January to July, 2014, 28 patients with thyroid cancer were treated with radical thyroidectomy in Xijing Hospital, fourth military Medical University. The sensitivity and specificity of the two methods were compared. Results A total of 40 suspicious nodules were detected in 28 patients, including 29 suspected parathyroid glands, 9 suspicious lymph nodes and 2 suspicious nodules. The total detection rate of parathyroid gland and lymph node were 27.5% (11 / 40) and 37.5% (15 / 40) respectively. The frozen pathological examination was consistent with the postoperative pathological examination, so the accuracy of rapid detection of lymph nodes and parathyroid gland was 100%, 93.1% (1 false positive) and 100%, respectively, according to the gold standard. The specificity was 97.0%. Conclusion the rapid detection of intraoperative puncture can accurately identify suspected lymph nodes, which is helpful to the protection and in situ preservation of parathyroid gland.
【作者單位】： 第四軍醫(yī)大學(xué)西京醫(yī)院甲乳血管外科;第四軍醫(yī)大學(xué)西京醫(yī)院病理科;
【基金】：國家自然科學(xué)基金(No.8157110197)
【分類號】：R653

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