【摘要】：目的:通過(guò)定標(biāo)活檢術(shù)評(píng)價(jià)結(jié)腸小息肉活檢鉗除治療效果及定標(biāo)活檢在結(jié)腸粘膜中的留存情況。方法:取由2012年1月至2014年7月經(jīng)電子結(jié)腸鏡檢查發(fā)現(xiàn)結(jié)腸小息肉,且直徑均5mm,共120例的患者,予以小息肉粘膜定標(biāo)后行活檢鉗除,經(jīng)過(guò)6個(gè)月、12個(gè)月、18個(gè)月的跟蹤隨訪,觀察是否有活檢后小息肉的復(fù)發(fā)或殘留,并觀察定標(biāo)活檢在腸道粘膜的存留時(shí)間及存留的效果,分析單次定標(biāo)成功率、標(biāo)記在腸道粘膜的存在情況、標(biāo)記局部黏膜的組織反應(yīng)及其并發(fā)癥等情況。同時(shí)分析定標(biāo)活檢鉗除的并發(fā)癥等情況。結(jié)果:120例患者共有132枚息肉,行定標(biāo)活檢鉗除,其中2例出現(xiàn)穿刺后血腫,未行定標(biāo)及活檢鉗除,4例息肉定標(biāo)成功后鉗除息肉時(shí)將已定標(biāo)黏膜一并鉗除,沖洗后未見定標(biāo)液殘留,且局部黏膜組織較薄,為預(yù)防穿孔,未做再次定標(biāo),故即時(shí)息肉鉗除率98.33%,單次定標(biāo)成功率86.36%,總有效率95.45%。共有114例患者行腸鏡復(fù)查,其中2例直腸小息肉復(fù)發(fā),復(fù)發(fā)率1.75%,隨訪超過(guò)6個(gè)月、12個(gè)月、18個(gè)月的患者中,定標(biāo)存在率分別為80.16%、75.40%、74.60%。結(jié)論:活檢鉗鉗除結(jié)腸小息肉(直徑0.5cm)的治療簡(jiǎn)便快捷,療效肯定,用定標(biāo)活檢術(shù)評(píng)價(jià)結(jié)腸小息肉活檢鉗除法更為科學(xué)及精確。定標(biāo)活檢術(shù)在腸道黏膜中具有標(biāo)識(shí)清晰,留存時(shí)間較長(zhǎng),適合腸道疾病的縱向?qū)Ρ妊芯?臨床推廣意義較大。
[Abstract]:Objective: to evaluate the therapeutic effect of biopsy and forceps for small polyps of colon and the retention of biopsy in colonic mucosa. Methods: from January 2012 to July 2014, small polyps of colon were found by electronic colonoscopy in 120 patients (5mm in diameter), who underwent biopsy and forceps for 6 months and 12 months after calibrating the mucosa of small polyps. After 18 months of follow-up, the recurrence or residue of small polyps after biopsy was observed, and the retention time and effect of calibration biopsy in intestinal mucosa were observed, the success rate of single calibration was analyzed, and the existence of labeling in intestinal mucosa was analyzed. Local mucosal tissue reaction and its complications were labeled. At the same time, the complications of scaling biopsy forceps were analyzed. Results: 132 polyps were performed in 120 patients, 2 of them had hematoma after puncture, and 4 cases of polyps were removed when the polyps were removed successfully, and 4 cases of polyps were successfully calibrated, and the mucosa was removed simultaneously when the polyps were removed by the forceps, 2 of them had hematoma after puncture, and 4 of them had not been performed biopsy forceps and biopsy forceps. No residual calibration fluid was found after rinsing, and the local mucosal tissue was thinner. In order to prevent perforation and no re-calibration was made, the immediate polyps clamp rate was 98.33%, the success rate of single calibration was 86.36%, and the total effective rate was 95.45%. In 114 patients, the recurrence rate of rectal polyps was 1.75%. The calibration rates were 80.16%, 75.40% and 74.60% respectively in the patients who were followed up for more than 6 months, 12 months and 18 months respectively. The recurrence rates of rectal polyps were 80.16%, 75.40% and 74.60% respectively, and the recurrence rate of rectal polyps was 1.75%. Conclusion: biopsy forceps for the treatment of small polyps of colon (diameter 0.5cm) is simple, rapid and effective. It is more scientific and accurate to evaluate biopsy forceps for small polyps of colon by biopsy. Calibration biopsy has clear mark and long retention time in intestinal mucosa. It is suitable for longitudinal comparative study of intestinal diseases and is of great significance in clinical application.
【學(xué)位授予單位】：寧波大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R656.7

【參考文獻(xiàn)】

相關(guān)期刊論文 前2條

1 徐富星,岑戎;Turcot綜合征[J];中國(guó)實(shí)用內(nèi)科雜志;2000年02期

2 閻曉初,柳鳳軒,房殿春,羅元輝,魯榮;大腸癌細(xì)胞周期調(diào)控因子表達(dá)與微衛(wèi)星不穩(wěn)定性的關(guān)系[J];中華腫瘤雜志;2000年02期

相關(guān)碩士學(xué)位論文 前1條

1 趙嵐;胃黏膜定標(biāo)活檢技術(shù)臨床應(yīng)用價(jià)值探討[D];浙江大學(xué);2008年

，

本文編號(hào)：2445435