【摘要】：目的:比較早期乳腺癌保乳術(shù)后采用三維適形放射治療(three-dimensional conformal radiotherapy,3DCRT)和電子組織補(bǔ)償(electronic tissuecompensation,eComp)兩種不同放療方案的劑量學(xué)差異。方法:60例早期乳腺癌保乳術(shù)后放療患者,在專用軟件上分別設(shè)計(jì)3DCRT和eComp 2種方案并比較設(shè)計(jì)方案所耗費(fèi)時(shí)間、輻射劑量機(jī)器監(jiān)測(cè)單位(monitor unit,MU)、腫瘤靶區(qū)劑量覆蓋和正常組織器官受照射劑量等參數(shù)之間的差異。結(jié)果:設(shè)計(jì)放療方案所耗費(fèi)時(shí)間,eComp約比3DCRT多10 min,差異有統(tǒng)計(jì)學(xué)意義(P=0.000)。3DCRT和eComp的平均MU分別為(300±12)、(302±11)MU(P=0.059)。2種方案都能滿足腫瘤靶區(qū)的劑量覆蓋標(biāo)準(zhǔn);采用eComp方案,肺、心臟和皮膚劑量更低(P0.05)。結(jié)論:在保證腫瘤靶區(qū)得到足量照射的前提下,eComp技術(shù)可以降低肺、心臟和皮膚的受照射劑量。
[Abstract]:Aim: to compare the dosimetric differences between three-dimensional conformal radiotherapy (three-dimensional conformal radiotherapy,3DCRT) and electronic tissue compensation (electronic tissuecompensation,eComp) after breast-conserving surgery for early breast cancer. Methods: 60 patients with early breast cancer treated by post-breast-conserving radiotherapy were divided into two groups: 3DCRT and eComp, and the time-consuming time of the design was compared. The radiation dose monitoring unit (monitor unit,MU) was designed on the special software. The difference between tumor target dose coverage and irradiation dose of normal tissues and organs. Results: the eComp was about 10 min, longer than that of 3DCRT (P < 0.001), and the average MU of 3DCRT and eComp was (300 鹵12), respectively. (302 鹵11) MU (P < 0.059). Both of the two schemes could meet the dose coverage criteria of tumor target area. Using eComp regimen, lung, heart and skin doses were lower (P0.05). Conclusion: eComp can reduce the radiation dose of lung, heart and skin on the premise of sufficient dose of radiation to tumor target area. [WT5 "HZ] conclusion: [WT5" BZ] [WT5 "BZ]
【作者單位】： 重慶醫(yī)科大學(xué)附屬第一醫(yī)院腫瘤科;
【基金】：重慶市衛(wèi)計(jì)委醫(yī)學(xué)科研計(jì)劃資助項(xiàng)目(編號(hào):2015MSXM012)
【分類號(hào)】：R737.9
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本文編號(hào)：2440647