【摘要】：目的 分析低分子肝素對股骨轉(zhuǎn)子間骨折圍術(shù)期失血量的影響,為臨床應(yīng)用低分子肝素預(yù)防股骨轉(zhuǎn)子間骨折圍術(shù)期抗凝提供參考。 方法 回顧性分析我科2008年1月至2014年12月股骨轉(zhuǎn)子間骨折采用閉合復(fù)位髓內(nèi)釘?shù)幕颊?按低分子肝素抗凝時間方案的不同,男女分別計算比較圍術(shù)期失血量和隱性失血量,分析低分子肝素對失血量的影響。 結(jié)果 男性病人組：(1)術(shù)后第1天,術(shù)前術(shù)后均不抗凝組總失血量、隱性失血量顯著大于術(shù)前術(shù)后均抗凝組,差異有統(tǒng)計學(xué)意義(P0.05)；術(shù)后抗凝組與另外兩組比較總失血量無統(tǒng)計學(xué)差異(P0.05)。(2)術(shù)后第3天,術(shù)前術(shù)后均不抗凝組、術(shù)后抗凝組、術(shù)前術(shù)后均抗凝組三組患者總失血量、隱性失血量,三組之間均無統(tǒng)計學(xué)差異(P0.05)。 女性病人組：(1)術(shù)后第1天,術(shù)前術(shù)后均不抗凝組、術(shù)后抗凝組、術(shù)前術(shù)后均抗凝組三組患者總失血量、隱性失血量,三組之間無統(tǒng)計學(xué)差異(P0.05)。(2)術(shù)后第3天,術(shù)前術(shù)后均不抗凝組、術(shù)后抗凝組、術(shù)前術(shù)后均抗凝組三組患者總失血量、隱性失血量,三組之間無統(tǒng)計學(xué)差異(P0.05)。 結(jié)論 低分子肝素可有效抑制血栓的形成,且引起的出血風險很小,臨床上對股骨轉(zhuǎn)子間骨折病人應(yīng)術(shù)前術(shù)后常規(guī)抗凝。
[Abstract]:Objective to analyze the effect of low molecular weight heparin (LMWH) on perioperative blood loss of intertrochanteric fracture of femur, and to provide reference for clinical application of LMWH to prevent anticoagulation during perioperative period of intertrochanteric fracture of femur. Methods the patients with intertrochanteric fracture of femur treated with closed reduction intramedullary nail from January 2008 to December 2014 were analyzed retrospectively according to low molecular weight heparin anticoagulant time (LMWH). The effect of low molecular weight heparin (LMWH) on blood loss was analyzed. Results in male patients group: (1) on the 1st day after operation, the total blood loss and recessive blood loss were significantly higher in the non-anticoagulant group than in the pre-operative and post-operative anticoagulant group (P0.05); There was no significant difference in total blood loss between the anticoagulant group and the other two groups (P0.05). (2) on the 3rd day after operation, no anticoagulant group before and after operation, anticoagulant group after operation, total blood loss and recessive blood loss in the three groups before and after operation. There was no statistical difference among the three groups (P0.05). Female patients group: (1) on the first day after operation, no anticoagulant group, postoperative anticoagulant group, preoperative and postoperative anticoagulant group, three groups of patients with total blood loss, recessive blood loss, There was no significant difference among the three groups (P0.05). (2) on the 3rd day after operation, no anticoagulant group, postoperative anticoagulant group, preoperative and postoperative anticoagulant group, total blood loss, recessive blood loss, There was no statistical difference among the three groups (P0.05). Conclusion Low-molecular-weight heparin can effectively inhibit the formation of thrombus, and the risk of bleeding is very small. The routine anticoagulant therapy should be performed before and after operation in patients with intertrochanteric fracture of femur.
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R687.3

【共引文獻】

相關(guān)期刊論文 前10條

1 楊越華;蔣雷生;;髖膝關(guān)節(jié)置換及髖部骨折內(nèi)固定術(shù)后隱性失血[J];國際骨科學(xué)雜志;2011年05期

2 韓天宇;周大鵬;田競;項良碧;;INTERTAN治療老年股骨粗隆間骨折圍手術(shù)期隱性失血的初步分析[J];成都醫(yī)學(xué)院學(xué)報;2013年03期

3 鄧海峰;胡思斌;鄭繼會;馬杰;王江靜;劉道闊;林亮;劉德峰;張永波;;PFNA內(nèi)固定治療股骨粗隆間骨折術(shù)后隱性失血的影響因素[J];中國骨與關(guān)節(jié)損傷雜志;2013年08期

4 鄒華章;唐程;佟方明;付建華;柳昱;陸銳均;黃有志;;人工股骨頭置換術(shù)治療老年股骨粗隆間骨折療效分析[J];中國骨與關(guān)節(jié)損傷雜志;2013年08期

5 侯國進;周方;張志山;姬洪全;田耘;;不同內(nèi)固定方式治療老年股骨粗隆間骨折圍手術(shù)期的失血特點分析[J];北京大學(xué)學(xué)報(醫(yī)學(xué)版);2013年05期

6 黃偉;許力月;邵森W，

本文編號：2414872